Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Tuesday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (51-57) visit the Cincinnati Reds (51-55) on Tuesday. First pitch from Great American Ball Park is scheduled for 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 6-2

The Cubs had a 2-game winning streak snapped on Monday with a 7-1 loss against the Reds while failing to cover as -109 road favorites. 1B Michael Busch had the team’s only RBI with a solo HR while RHP Jameson Taillon allowed 6 ER in 4 1/3 innings to take the loss.

Cincinnati snapped a 2-game losing streak with the win as a +101 home underdog. CF TJ Friedl had a 3-run HR and LF Will Benson had a 2-run shot. RHP Carson Spiers allowed 0 ER in 5 innings to pick up the win.

Cubs at Reds projected starters

LHP Justin Steele vs. TBD

Steele (2-4, 3.08 ERA) makes his 17th start. He has a 1.06 WHIP, 2.15 BB/9 and 8.50 K/9 in 96 1/3 IP.

  • Last start: No-decision, 5 1/3 IP, 2 ER, 6 H, 3 BB, 4 K in 3-2 loss against Milwaukee Brewers Wednesday.
  • Career vs. Reds: 2-4, 5.75 ERA (40 2/3 IP, 26 ER), 56 H, 15 BB, 45 K in 8 starts

The Reds had not named a starter at time of publication.

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Cubs at Reds odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:13 a.m. ET.

  • Moneyline (ML): Cubs -130 (bet $130 to win $100) | Reds +105 (bet $100 to win $105)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+125) | Reds +1.5 (-155)
  • Over/Under (O/U): 9 (O: -115 | U: -105)

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Cubs at Reds picks and predictions

Prediction

Reds 4, Cubs 3

Moneyline

BET REDS (+105).

The Reds have dominated their season series against the Cubs 6-2 thus far while going 4-1 at home. They have won 4 of their last 6 games and rebounded from their road trip with a 7-run game Monday. Expect Cincinnati to continue to gain momentum against the division-worst Cubs on Tuesday.

Run line/Against the spread

PASS.

There is no value on the Reds run line in this matchup.

Over/Under

BET UNDER 9 (-105).

The Cubs have hit the Under in 8 of their last 10 while the Reds have hit the Under in 7 of their last 10. Chicago has scored 3 runs or fewer in 8 of its last 10 and 2 runs or fewer in 4 of its last 10 while Cincinnati has scored 3 runs or less in 3 of its last 4.

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Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Monday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The Cincinnati Reds (50-55) welcome the Chicago Cubs (51-56) to Great American Ball Park Monday for the 1st contest of a 3-game series. First pitch is set for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 5-2

Chicago won at the Kansas City Royals 7-3 Sunday, closing as a +161 underdog. The Cubs took the final 2 games of the 3-game set, tallying 16 total runs in the 2 wins. The Cubs are 24-31 on the road this season and 7-3 in their last 10 away games. Chicago is 51-56 against the spread (ATS).

The Reds lost at the Tampa Bay Rays 2-1 Sunday as -107 underdogs. They were underdog in all 3 games against the Rays, losing Saturday and Sunday after taking Friday’s opener. Cincinnati has won 3 of its last 5 and is 8-7 over its last 13. This is Cincinnati’s 1st homestand after the All-Star break — they went 3-5 on an 8-game trip to start the 2nd half. Cincy is 5-2 over its last 7 home games — they are 25-28 at Grate American Ball Park and 57-48 ATS overall.

Cubs at Reds projected starters

RHP Jameson Taillon vs. RHP Carson Spiers

Taillon (7-5, 2.96 ERA) makes his 18th start. He has a 1.15 WHIP, 1.9 BB/9 and 7.0 K/9 through 100 1/3 innings.

  • Last start: Loss, 7 1/3 IP, 1 ER, 4 H, 3 BB, 3 K in 1-0 home defeat vs. Milwaukee Brewers Tuesday
  • 2024 away splits: 2-2, 3.28 ERA (46 2/3 IP, 17 ER), 1.16 WHIP, 6 HR, 5.8 K/9 in 8 starts
  • Career vs. Reds: 5-5, 4.79 ERA (88 1/3 IP, 47 ER), 1.36 WHIP, 8.6 K/9 in 16 starts
  • First time facing Reds this season

Spiers (3-2, 3.83 ERA) makes his 6th start and 11th appearance. He has a 1.26 WHIP, 1.7 BB/9 and 7.9 K/9 through 47 innings.

  • Last start: Win, 5 IP, 3 ER, 6 H, 0 BB, 9 K in 7-4 home win over Miami Marlins July 12
  • 2024 home splits: 2-1, 3.94 ERA (32 IP, 14 ER), 1.38 WHIP, 4 HR, 8.2 K/9 in 7 appearances (3 starts)
  • Career vs. Cubs: 0-0, 2.79 ERA (9 2/3 IP, 3 ER), 1.24 WHIP, 13 K/9 in 2 appearances (1 start)
  • 2024 vs. Cubs: 1 relief outing, 5 2/3 IP, 0 ER, 4 H, 1 BB, 7 K in 4-2 home loss June 9

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cubs at Reds odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 9:33 p.m. ET.

  • Moneyline (ML): Cubs -112 (bet $112 to win $100) | Reds -104 (bet $104 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+142) | Reds +1.5 (-172)
  • Over/Under (O/U): 9 (O: +100 | U: -122)

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Cubs at Reds picks and predictions

Prediction

Cubs 5, Reds 3

Moneyline

BET CUBS (-112).

The Cubs haven’t played overly well on the road, but they will have the pitching advantage. Meanwhile, the Reds are also one of the worst teams in the majors as home underdogs at 6-11 straight up and 8-9 ATS.

Cincinnati hasn’t played at home since July 14, and it has gone 5-5 in its last 10 at GABP. Spiers hasn’t pitched well as of late either, having allowed 3 or more runs in 4 of his last 5 starts.

Considering the trends, BACK CUBS (-112).

Run line/Against the spread

PASS.

There’s no good value here. The Reds (+1.5) as home underdogs are too expensive to take at -172, and the Cubs (-1.5, +142) are too risky, especially considering how poorly they’ve played on the road.

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Over/Under

BET UNDER 9 (-122).

The Cubs are 3-5 O/U in Taillon’s last 8 starts, and they have gone Under in 6 of their last 8. Chicago has scored 3 or fewer in 6 of 8 as well, so it hasn’t had an overly consistent offense. The Cubs are 45-58-4 O/U on the season.

The Reds, who are 46-55-4 O/U on the season, have gone Under in 3 straight and in 5 of their last 6 games. Cincinnati has scored 4 runs in its last 3 games — 1 total run in its last 2.

Neither team is batting well right now. TAKE UNDER 9 (-122).

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Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Saturday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (31-33) and Cincinnati Reds (31-33) play the 3rd game of a 4-game NL Central series Saturday. First pitch at Great American Ball Park is slated for 4:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Cincinnati leads 4-1

The Cubs lost Friday’s game 3-2 and are 2-9 with a 4.85 ERA over their last 11 outings away from Wrigley Field.

The Reds have taken the 1st 2 games of this series and are 6-0 since June 2. Cincinnati is 9-3 with a plus-18 run differential over its last 12 games.

Cubs at Reds projected starters

RHP Ben Brown vs. LHP Andrew Abbott

Brown (1-2, 3.33 ERA) is tabbed for his 8th start and 15th appearance. He has a 1.09 WHIP, 3.2 BB/9 and 10.7 K/9 in 51 1/3 IP.

  • Last outing: Loss, 5 IP, 5 ER, 6 H, 1 BB, 6 K in 5-2 home setback vs. Reds Sunday (1st career game vs. Cincinnati)
  • Owns a 2.83 ERA as a starter

Abbott (4-5, 3.39 ERA) is tabbed for his 13th start. He has a 1.14 WHIP, 2.4 BB/9 and 6.8 K/9 in 69 IP.

  • Last outing: Win, 6 IP, 3 ER, 7 H, 1 BB, 6 K in 13-3 victory at Colorado Rockies Monday
  • Career vs. Cubs: 0-0, 4.66 ERA (9 2/3 IP, 5 ER), 9 H, 5 BB, 10 K in 2 starts

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Cubs at Reds odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:02 a.m. ET.

  • Moneyline: Cubs +100 (bet $100 to win $100) | Reds -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-200) | Reds -1.5 (+150)
  • Over/Under (O/U): 9 (O: -110 | U: -110)

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Cubs at Reds picks and predictions

Prediction

Cubs 6, Reds 4

Moneyline

Cincinnati is 6-2 over the last 8 series meetings. The CUBS (+100) are 2-9 across their last 11 road games.

At 4.41 runs per game and 4.16 RPG allowed, Cincy figures to be a better-than-.500 club. The Reds have been a good betting proposition of late and will likely be a solid one in the immediate future. But the pitching match-up changes the equation for Saturday.

Abbott has been quite fortunate to pitch through the lessened traffic of a .246 batting average on balls in play, and per ESPN, current Chicago batters own an aggregate .775 OPS against him.

Aside from his Sunday clunker against the Reds (which figures to be recency bias overestimated by bettors), Brown has been sharp in this, his rookie campaign. The 24-year-old has fanned 34 batters in his last 23 2/3 IP, and the Reds own a low-contact .673 OPS against righties.

Consider a partial-unit play on CHICAGO (+100).

Run line/Against the spread

PASS: The ML option injects less juice and teases out more leverage.

Over/Under

Some overall team batting and pitching gravity pegs both clubs as being Over leans in general: The NL Central clubs figure to be higher-scoring teams with gettable pitching.

With some added fade of Abbott in particular and with the game being in hitter-friendly Great American with a daytime start, the OVER 9 (-110) has value.

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Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Friday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (31-32) and Cincinnati Reds (30-33) meet Friday as they continue a 4-game NL Central series. First pitch at Great American Ball Park is slated for 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Cincinnati leads 3-1

The Cubs dropped Thursday’s series opener 8-4. Chicago lost 2-0 and 4-3 leads in the contest in seeing its team ERA since May 29 rise to 5.61.

The Reds are back at home after a 4-1 road trip which opened by taking 2 of 3 against these Cubs at Wrigley Field last weekend. Cincinnati is 8-3 with a plus-17 run differential over its last 11 games.

Cubs at Reds projected starters

LHP Justin Steele vs. LHP Nick Lodolo

Steele (0-2, 4.10 ERA) is tabbed for his 8th start. He has a 1.21 WHIP, 2.7 BB/9 and 8.7 K/9 in 37 1/3 IP.

  • Last outing: No-decision, 5 IP, 1 ER, 7 H, 4 BB, 5 K in 7-5 win vs. Cincinnati Reds Sunday
  • Career vs. Reds: 2-3, 6.68 ERA (33 2/3 IP, 25 ER), 51 H, 14 BB, 38 K in 9 games (7 starts)

Lodolo (5-2, 3.11 ERA) is making his 9th start. He has a 0.99 WHIP, 1.9 BB/9 and 9.5 K/9 in 46 1/3 IP.

  • Last outing: Win, 6 IP, 2 ER, 7 H, 1 BB, 3 K in 5-2 win at Chicago Cubs Sunday
  • Career vs. Cubs: 1-1, 4.02 ERA (15 2/3 IP, 7 ER), 16 H, 10 BB, 14 K in 3 starts

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Cubs at Reds odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:07 a.m. ET.

  • Moneyline: Cubs -105 (bet $105 to win $100) | Reds -115 (bet $100 to win $115)
  • Against the spread (ATS): Cubs -1.5 (+155) | Reds +1.5 (-190)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Cubs at Reds picks and predictions

Prediction

Reds 6, Cubs 4

Moneyline

Cincinnati is 5-2 over the last 7 series meetings. The Cubs are 2-8 across their last 10 road games.

Per ESPN, Reds current batters own an aggregate .904 OPS against Steele. At 4.43 runs per game and 4.19 RPG allowed, Cincy figures to be a better-than-.500 club. Bettors are likely undervaluing the Reds somewhat.

BACK CINCINNATI (-115).

Run line/Against the spread

PASS: Look to the ML for the best leverage in this matchup.

Over/Under

The Over cashed Thursday and is 3-0-1 across the last 4 series meetings.

Cincinnati is at its best against port-siders, and both lineups saw these same hurlers last week. Expect some good swings backed by that familiarity, against both the starters and bullpens.

On a breeze-blowing-out night at a home-run ballpark, TAKE THE OVER 9 (-105).

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Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Thursday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (31-31) and Cincinnati Reds (29-33) meet Thursday as they swing into a 4-game NL Central series. First pitch at Great American Ball Park is slated for 7:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Cincinnati leads 2-1

The Cubs are coming off back-to-back 7-6 triumphs over the Chicago White Sox and are 3-1 across their last 4 games after enduring a rough 1-8 stretch at the end of May.

The Reds are back at home after a 4-1 road trip which opened by taking 2 of 3 against these Cubs at Wrigley Field last weekend. Cincinnati is 8-3 with a plus-17 run differential over its last 11 games.

Cubs at Reds projected starters

RHP Javier Assad vs. RHP Hunter Greene

Assad (4-1, 2.27 ERA) makes his 13th start. He has a 1.18 WHIP, 3.7 BB/9 and 8.7 K/9 in 63.1 IP.

  • Last outing: No-decision, 5 1/3 IP, 2 ER, 5 H, 3 BB, 7 K in 5-4 loss vs. Cincinnati Reds Friday
  • Career vs. Reds: 0-1, 2.30 ERA (31 1/3 IP, 8 ER), 29 H, 12 BB, 32 K in 6 games (4 starts)
  • Has benefited from a .256 batting average on balls in play in inning lead-off situations and a .154 BABIP in high-leverage scenarios

Greene (3-2, 3.44 ERA) is making his 13th start. He has a 1.16 WHIP, 3.8 BB/9 and 9.7 K/9 in 70.2 IP.

  • Last outing: No-decision, 6 IP, 5 ER, 3 H, 5 BB, 5 K in 5-4 loss vs. Cincinnati Reds Friday
  • Career vs. Cubs: 3-1, 4.33 ERA (27 IP, 13 ER), 14 H, 12 BB, 35 K in 5 starts
  • Makes this start on 4 days’ rest: has yielded just a .655 OPS on such rest over his career

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Cubs at Reds odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:06 a.m. ET.

  • Moneyline: Cubs +105 (bet $100 to win $105) | Reds -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-175) | Reds -1.5 (+145)
  • Over/Under (O/U): 9.5 (O: -105 | U: -115)

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Cubs at Reds picks and predictions

Prediction

Reds 6, Cubs 4

Moneyline

The Cubs are 1-5 over their last 6 road games. The Reds are 4-2 across the last 6 series meetings.

Peg Cincinnati as having a bit of an unfortunate record with its 4.37 runs per game against 4.19 allowed. The Reds’ bullpen is in good shape after an off day, and Chicago’s relief corps is in fatigue territory. The back end of that Chicago pen has multiple bodies likely unavailable Thursday.

Chicago batters own a .614 OPS since May 13. Cincinnati has won 5 straight series openers and is a value in this spot. BACK THE REDS (-125).

Run line/Against the spread

Some lean toward the home team here, but figure the return on the Reds minus a cushion being a tad light. PASS.

Over/Under

The last 8 Cubs games have cashed Over tickets 7 times. The total has gone Over in 12 of Cincinnati’s last 17 games against Chicago.

Both starters have expected-ERA figures that would indicate they are most likely overrated in their effect on tamping down scores. Mix in a breeze-blowing-out forecast in home-run favorable Great American Ball Park and a fatigued back end of the Chicago bullpen, and the OVER 9.5 (-105) is the play here.

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Chicago Cubs vs. Cincinnati Reds odds, picks and predictions

Analyzing Sunday’s Chicago Cubs vs. Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (72-64) face the Cincinnati Reds (71-67) on Sunday to end a 4-game series. First pitch from the Great American Ballpark is at 12:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 7-5

After splitting a doubleheader on Friday, Saturday’s game was a classic pitching duel between 2 teams fighting to make the playoffs.

The Reds won 2-1 as LHP Andrew Abbott threw 6 1/3 innings allowing just 4 hits, including a solo HR to Cubs 3B Jeimer Candelario. Chicago’s RHP Javier Assad, who started this season as a relief pitcher, threw 8 scoreless innings, but the Cubs RHP Mark Leiter Jr, promptly loaded the bases in the bottom of the 9th and the Reds won on a fielder’s choice by RF Hunter Renfroe.

Cubs vs. Reds projected starters

RHP Jameson Taillon vs. RHP Carson Spiers

Taillon (7-9, 5.62 ERA) makes his 25th start. He has a 1.35 WHIP, 2.4 BB/9 and 7.8 K/9 in 121 2/3 innings.

  • Last start: Loss, 6 IP, 4 ER, 9 H, 0 BB, 6 K in 6-2 loss vs. the Milwaukee Brewers on Monday
  • 2023 road stats: 4-3, 5.34 ERA (55 2/3 IP, 33 ER) in 11 starts
  • Career vs. Reds: 5-5, 4.57 ERA (82 2/3 IP, 42 ER) in 15 starts

Spiers is making his MLB debut. He is 8-3 with a 3.69 ERA with the AA Chattanooga Lookouts and has a 1.34 WHIP, 4.4 BB/9 and 11.5 K/9 in 83 innings.

  • Last start: No-decision, 5 IP, 2 ER, 2 H, 2 BB, 8 K in an 6-5 home loss to the Tennessee Smokies on Sunday
  • Allows a .211 opponent batting average against righties and .243 versus lefties.

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Cubs vs. Reds odds

Provided by FanDuel Sportsbook access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:53 a.m. ET.

  • Moneyline (ML): Cubs -134 (bet $134 to win $100) | Reds +114 (bet $100 to win $114)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+116) | Reds +1.5 (-140)
  • Over/Under (O/U): 11 (O: -112 | U: -108)

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Cubs vs. Reds picks and predictions

Prediction

Cubs 8, Reds 7

Moneyline

The Cubs are 17-13 as a road favorite while the Reds are 21-24 as a home ‘dog. And while the Reds this year have been great ATS as an underdog (67.3%), they only post a 49.5% win percentage. The Reds may cover but the Cubs should win this game, especially against a rookie pitcher.

BET CUBS -134.

Run line/Against the spread

The Reds have been the best team ATS this year. And, like the Baltimore Orioles last year, the Reds are covering because the sportsbooks were not expecting the team to be good this year. Of their 138 games, the Reds have been underdogs in 107 of them, covering in 72 of those games (67.3%).

That being said, there is more value in picking the Cubs moneyline than the Reds ATS so I would PASS and stay with the moneyline.

Over/Under

After Saturday night’s pitching duel, expect the offense of both teams to return, but note that the Cubs have gone Under in their last 6 games and the Reds in their last 7.

Despite that streak the overall trends point to more runs. Coming off a loss the Cubs have the 4th best Over record (35-28) in MLB, while the Reds have the 5th best Over record (38-32) after a win.

The sportsbooks also expect a high scoring game, hence their line. But I still LEAN OVER 11 (-112).

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Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Saturday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (72-63) will play the 3rd game of a 4-game series against the Cincinnati Reds (70-67) Saturday at Great American Ball Park. First pitch is scheduled for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 6-5

On Friday, the Cubs split a doubleheader against the Reds, winning the 1st game 6-2 and losing the 2nd contest 3-2. Chicago has tallied a 7-3 record in its last 10 games, putting it only 3 1/2 games behind the Milwaukee Brewers for 1st place in the NL Central.

In Friday’s 2nd game against the Cubs, OF Jake Fraley made his 1st start since Aug. 3, and he registered 3 hits in his return to help the Reds secure the win. Cincinnati is 4-6 in its last 10 contests and is 3 games behind Chicago for 2nd place in the NL Central.

Cubs at Reds projected starters

RHP Javier Assad vs. LHP Andrew Abbott

Assad (3-2, 2.96 ERA) makes his 7th start. He has a 1.20 WHIP, 3.6 BB/9 and 6.8 K/9 through 79 IP.

  • Last start: Win, 7 IP, 1 ER, 3 H, 2 BB, 7 K in a 10-1 road victory over the Pittsburgh Pirates Sunday
  • Road stats: 3-0, 2.16 ERA (33 1/3 IP, 8 ER) in 3 starts and 6 relief appearances.
  • Career vs. Reds: 0-1, 3.00 ERA (18 IP, 6 ER) in 2 starts and 2 relief appearances.

Abbott (8-4, 3.35 ERA) makes his 17th start. He has a 1.22 WHIP, 3.5 BB/9 and 10.0 K/9 through 88 2/3 IP.

  • Last start: Loss, 3 1/3 IP, 3 ER, 5 H, 3 BB, 6 K in a 4-1 road defeat to the San Francisco Giants Monday
  • Home stats: 3-2, 2.84 ERA (44 1/3 IP, 14 ER) in 7 starts.
  • Career vs. Cubs: 0-0, 10.80 ERA (3 1/3 IP, 4 ER) in 1 start.

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Cubs at Reds odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:30 a.m. ET.

  • Moneyline (ML): Cubs -115 (bet $115 to win $100) | Reds -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+140) | Reds +1.5 (-165)
  • Over/Under (O/U): 9.5 (O: -110 | U: -110)

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Cubs at Reds picks and predictions

Prediction

Cubs 5, Reds 4

Moneyline

Following the doubleheader Friday, I’ll back the CUBS (-115) on the road in Saturday’s matchup. Assad has been a formidable starter since joining Chicago’s rotation, and Abbott has given up 3 runs or more in 3 of his last 5 starts for Cincinnati.

Run line/Against the spread

While the Reds should stay within striking distance against the Cubs, go ahead and PASS on the run line in this divisional showdown. Taking Cincinnati to keep the game within a run isn’t worth the risk at -165 odds.

Over/Under

UNDER 9.5 (-110) is the lean in this game despite Great American Ball Park being a hitter-friendly venue. The Cubs are 6-4 to the Under in their last 10 games overall, while the Reds are 7-3 to the Under in their last 10.

Also, the Under has been achieved in 3 consecutive meetings, and 2 of those meetings took place in Cincinnati.

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Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Monday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

The Chicago Cubs (1-2) will begin a 3-game series against the Cincinnati Reds (2-1) on Monday at Great American Ball Park. First pitch is scheduled for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Cubs went 11-8 vs, the Reds in 2022

The Cubs wrapped up a 3-game series at Wrigley Field against the Milwaukee Brewers losing 9-5 on Sunday, the 2nd straight loss after a win on Opening Day. SS Dansby Swanson has gotten off to a great start for Chicago, going 7-for-12 with 2 RBIs in his first 3 games with his new team.

The Reds went 2-1 in their 3-game opening series against the Pittsburgh Pirates. Cincinnati won 3-1 on Sunday as Graham Ashcraft pitched 7 strong inning (4 H, 1 ER, 1 BB 6 K’s). Jason Vosler, filling in at 1B with Joey Votto injured, hit a solo HR.

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Cubs at Reds projected starters

LHP Drew Smyly vs. RHP Connor Overton

Smyly was 7-8 in 22 starts in 2022 with a 3.47 ERA, 1.19 WHIP, 2.2 BB/9, and 7.7 K.9 in 106 1/3 IP.

  • Has made 22-plus starts in back-to-back seasons
  • His 3.47 ERA in 2022 was the best mark of his career in a season where he started in 10-plus games since 2015

Overton was 1-0 in 4 starts last season with a 2.73 ERA, 0.97 WHIP, 3 BB/9, and 3.8 K/9 in 33 IP.

  • Has yet to make more than 4 starts in a season
  • Didn’t allow more than 2 runs in any of his 4 starts in 2022

Cubs at Reds odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:12 a.m. ET.

  • Moneyline (ML): Cubs -125 (bet $125 to win $100) | Reds +105 (bet $100 to win $105)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+135) | Reds -1.5 (-160)
  • Over/Under (O/U): 9 (O: +100 | U: -120)

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Cubs at Reds picks and predictions

Prediction

Cubs 4, Reds 3

Moneyline

Even though the Reds have surprisingly begun the season with a winning record, I’ll back the CUBS (-125) in this NL Central matchup.

Run line/Against the spread

REDS +1.5 (-160) is how I’d wager on the spread, though, I’d prefer to get it at -150 odds or better if available. Cincinnati is capable of keeping this game close at home with neither team getting consistency from its bats to begin the season.

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Over/Under

UNDER 9 (-120) is the pick in this contest despite Great American Ball Park being a favorable hitting venue. Smyly and Overton should have solid outings against these lineups, and fewer than 9 runs have been scored in 6 of the last 10 meetings.

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Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Wednesday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks and predictions.

The Chicago Cubs (73-88) and Cincinnati Reds (62-99) cap off a 6-game home-and-home set Wednesday at Great American Ball Park. First pitch is scheduled for 4:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cubs vs. Reds odds with MLB picks and predictions.

Season series: Chicago leads 10-8

Chicago took all 3 games at Wrigley Field (Friday-Sunday), and now Cincinnati has taken the first 2 games at Great American in this odd, season-ending 6-pack. The Cubs had won 7 games in a row and 11 of 12 before arriving in Cincinnati Monday.

The Reds snapped a 6-game losing skid with Monday’s triumph over Chicago, but Cincy continues to struggle with the bats. The Reds have scored 6 runs on 12 hits in this series; they have slashed an anemic .177/.254/.274 (.528 OPS) since Sept. 22. Over that stretch, Cincinnati has scored just 2.0 runs per game.

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Cubs at Reds projected starters

RHP Adrian Sampson vs. RHP Graham Ashcraft

Sampson (4-5, 3.10 ERA)  has appeared in 20 games, making 18 starts. He has a 1.21 WHIP, 2.3 BB/9 and 6.2 K/9 through 101 2/3 IP.

  • Has registered a 1.60 ERA over his last 7 starts
  • Has logged a 2.42 ERA over his last 5 starts against Cincinnati (2021-22)

Ashcraft (5-5, 4.52 ERA) has authored a 1.40 WHIP, 2.3 BB/9 and 6.1 K/9 through 99 2/3 IP across 18 starts.

  • Has allowed 26 base runners in 11 1/3 IP against Chicago this season (11.91 ERA)
  • Owns a 3.98 home ERA

Cubs at Reds odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:30 a.m. ET.

  • Moneyline: Cubs -125 (bet $125 to win $100) | Reds +102 (bet $100 to win $102)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+127) | Reds +1.5 (-165)
  • Over/Under (O/U): 8.5 (O: -117 | U: -103)

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Cubs at Reds picks and predictions

Prediction

Cubs 5, Reds 4

Moneyline

Chicago is playing out the dog days of the season in a better collective frame of mind. Cincinnati is just limping to the finish line, and its offense has been abysmal.

The starting pitchers’ numbers and the batters they face Wednesday are compelling. That’s enough of a Cubs plus and Reds negative to provide some leverage on CHICAGO (-125), especially when you add in some value on the visitors’ side in the bullpen availability department.

Run line/Against the spread

Sampson does have some fade in his numbers. With the Reds getting last licks and Chicago being a club that plays a ton of 1-run games, PASS and focus on the Cubs’ ML play.

Over/Under

Likable in some run-scoring facets; unlikable in others. Same deal on run-prevention indicators. Call this one a tangle of mixed signals and STEER CLEAR.

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Chicago Cubs at Cincinnati Reds odds, picks and predictions

Analyzing Tuesday’s Chicago Cubs at Cincinnati Reds odds and lines, with MLB expert picks and predictions.

The Chicago Cubs (73-87) and Cincinnati Reds (61-99) play the second game of a 3-game set Tuesday at Great American Ball Park. First pitch is scheduled for 6:40 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cubs vs. Reds odds with MLB picks and predictions.

Season series: Cubs lead 10-7

The Cubs’ 7-game winning streak came to an end after a 3-1 loss Monday at the Reds. Chicago starter RHP Hayden Wesneski allowed 1 ER on 4 H with 6 K through 6 IP in the loss.

The Reds avoided recording their 100th loss of the season with Monday’s win. Cincinnati starter RHP Hunter Greene allowed 0 ER on 2 H with 8 K through 6 IP as the Reds snapped a 6-game losing skid.

The Reds have not lost 100 or more games since the 1982 season when they finished 61-101.

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Cubs at Reds projected starters

RHP Javier Assad vs. RHP Luis Cessa

Assad (2-2, 3.62 ERA) makes his 8th start and 9th appearance. He has a 1.55 WHIP, 5.3 BB/9 and 7.2 K/9 through 32 1/3 IP.

  • Last start: Win Thursday vs. the Philadelphia Phillies with 5 IP, 0 ER, 5 H, 2 BB and 3 K
  • Only career start vs. Reds: Loss Sept. 7 with 5 1/3 IP, 4 ER, 5 H, 1 BB and 6 K

Cessa (4-4, 4.76 ERA) makes his 10th start and 46th appearance. He has a 1.35 WHIP, 3.2 BB/9 and 6.5 K/9 through 75 2/3 IP.

  • Last start: No-decision Wednesday at the Pittsburgh Pirates with 6 IP, 3 ER, 6 H, 2 BB and 2 K
  • Has lost 3 of his last 4 decisions
  • 2022 vs. Cubs: 0-0 with a 7.00 ERA (9 IP, 7 ER) in 1 start and 4 relief appearances

Cubs at Reds odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:21 a.m. ET.

  • Moneyline (ML): Cubs -105 (bet $105 to win $100) | Reds -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+150) | Reds +1.5 (-200)
  • Over/Under (O/U): 8.5 (O: -103 | U: -117)

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Cubs at Reds picks and predictions

Prediction

Reds 3, Cubs 2

Moneyline

BET REDS (-115).

The Reds will stay motivated Tuesday to avoid losing their 100th game. Assad struggled last time he faced the Reds and Tuesday shouldn’t be any different.

Run line/Against the spread

PASS.

Reds +1.5 (-200) is too expensive to bet, and I wouldn’t take Cincinnati to win by multiple runs because this should be a close game.

Over/Under

BET UNDER 8.5 (-117).

The Under is 8-0 in Cessa’s last 8 starts and 6-3-1 in the Reds’ last 10 games. Expect another low-scoring affair between these teams.

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