Chicago Cubs at Boston Red Sox odds, picks and predictions

Analyzing Sunday’s Chicago Cubs at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (17-10) and Boston Red Sox (15-13) wrap up a 3-game series at Fenway Park Sunday. First pitch is scheduled for 7 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

The Cubs, who were -113 favorites, lost 17-0 in the 2nd game of the series Saturday with the Over (9) hitting in Boston. The loss snapped a 4-game winning streak for Chicago.

CF Ceddanne Rafaela finished with a HR and 7 RBIs for the Red Sox, who cashed as +104 underdogs. RF Tyler O’Neill also homered, helping Boston win for just the 2nd time in 5 games.

Cubs at Red Sox projected starters

RHP Hayden Wesneski vs. RHP Tanner Houck

Wesneski (2-0, 0.00 ERA) makes his 1st start and 3rd appearance. He has a 0.16 WHIP, 0.0 BB/9 and 4.3 K/9 in 6 1/3 IP.

  • Last outing: Win, 2 1/3 IP, 0 ER, 0 H, 0 BB, 1 K in relief appearance of 3-1 home victory vs. Houston Astros Thursday
  • Last start: No-decision, 2 IP, 1 ER, 2 H, 1 BB, 4 K in 3-2 win at St. Louis Cardinals July 28, 2023
  • 2023 stats: 3-5, 4.63 ERA (89 1/3 IP, 46 ER), 1.28 WHIP in 11 starts and 23 relief appearances
  • Has never faced Boston

Houck (3-2, 1.65 ERA) makes his 6th start. He has a 0.98 WHIP, 1.4 BB/9 and 8.8 K/9 in 32 2/3 IP.

  • Last start: Loss, 6 IP, 2 ER, 5 H, 3 BB, 4 K in 4-1 loss at Cleveland Guardians Tuesday
  • 2024 home stats: 1-1, 2.45 ERA (14 2/3 IP, 4 ER), 1.02 WHIP in 2 starts
  • Career vs. Cubs: 0-0, 4.50 ERA (2 IP, 1 ER), 1.50 WHIP in 2 relief appearances

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Cubs at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:57 a.m. ET.

  • Moneyline (ML): Cubs +110 (bet $100 to win $110) | Red Sox -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-175) | Red Sox -1.5 (+145)
  • Over/Under (O/U): 9 (O: -115 | U: -105)

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Cubs at Red Sox picks and predictions

Prediction

Red Sox 4, Cubs 3

Moneyline

It’s unlikely that Boston’s offense will be able to maintain Saturday’s level of production; however, Houck will probably have a better start than Wesneski. Houck has allowed 2 or fewer earned runs in 4 of 5 starts, while Wesneski hasn’t even pitched more than 4 innings since June 28, 2023.

The Red Sox, who were 15th in runs per game at 4.33 entering Saturday, can’t be trusted to keep scoring runs over the course of a full game, but Houck is a good bet to keep them in position to at least win the 1st 5 innings.

BET RED SOX 1ST 5 INNINGS (-140).

Run line/Against the spread

Boston has struggled to win back-to-back games recently — let alone by multiple runs. The Cubs are also a bit too expensive to cover +1.5 at -175.

PASS. Bet the ML and/or total instead.

Over/Under

The Over has hit in the 1st 2 games of this series, but between Boston’s offense regressing toward the mean and Houck likely limiting Chicago to 2 or fewer runs, we should see a lower-scoring game Sunday. While it is a small sample size, Wesneski also hasn’t given up a run yet in 6 1/3 innings.

BET UNDER 9 (-105).

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Chicago Cubs at Boston Red Sox odds, picks and predictions

Analyzing Saturday’s Chicago Cubs at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (17-9) and Boston Red Sox (14-13) play the middle contest a 3-game interleague series Saturday at Fenway Park. First pitch is scheduled for 4:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Cubs lead 1-0; Chicago won the series opener 7-1 behind LHP Shota Imanaga Friday as the Over (7.5) cashed

The Cubs have won 4 games in a row, all against AL teams, and Chicago has picked up 6 consecutive interleague victories dating back to April 13. The Over was a rarity Friday, as the Under is 5-2 in the past 7 games for the Cubbies while going 6-1 in the past 7 against AL clubs.

The Red Sox have dropped 3 of the past 4 games. The Over has hit in the past 2 outings, and the total has gone high at a slight 4-3-1 clip in the past 8 games for Boston.

Cubs at Red Sox projected starters

RHP Ben Brown vs. RHP Josh Winckowski

Brown (0-0, 3.72 ERA) makes his 3rd start and 7th appearance. He has a 1.03 WHIP, 2.8 BB/9 and 8.4 K/9 in 19 1/3 innings.

  • Last start: No-decision, 6 IP, 1 ER, 1 H, 2 BB, 4 K in 3-2 road win in 11 innings vs. Arizona Diamondbacks April 15
  • 2024 road splits: 0-0, 5.11 ERA, 9 H, 5 BB, 10 K in 12 1/3 IP in 2 starts and 1 relief appearance

Winckowski (1-1, 4.20 ERA) makes his 2nd start and 9th appearance. He has a 1.80 WHIP, 4.8 BB/9 and 10.8 K/9 in 15 innings.

  • Last start: No-decision, 3 1/3 IP, 1 ER, 3 H, 0 BB, 1 K in 6-1 road win vs. Pittsburgh Pirates Sunday
  • 2024 home splits: 0-1, 8.10 ERA, 13 H, 5 BB, 8 K in 6 2/3 IP in 4 relief appearances

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Cubs at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:10 a.m. ET.

  • Moneyline (ML): Cubs -120 (bet $120 to win $100) | Red Sox +100 (bet $100 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+135) | Red Sox +1.5 (-165)
  • Over/Under (O/U): 8.5 (O: -120 | U: +100)

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Cubs at Red Sox picks and predictions

Prediction

Cubs 5, Red Sox 4

Moneyline

The CUBS (-120) are a decent play as slight favorites in this middle contest.

There is plenty of concern here, as Boston is just 3-8 this season at Fenway Park. The Cubs (-115) are on a serious roll, too, and Chicago has won 5 in a row against AL teams, while posting a plus-32 run differential.

Run line/Against the spread

The Red Sox +1.5 (-165) will cost you plenty if you require a little bit of insurance and cannot fathom the idea of playing Boston straight up.

In Boston’s past 3 losses across the past 4 games, it has lost by 2 or more runs, with an average margin of defeat of 3.7 runs per game.

PASS.

Over/Under

OVER 8.5 (-120) is a worth a look in this battle between Brown and Winckowski. It’s not likely to be a pitcher’s duel, and neither will go very deep into the game. The bullpens will be thrust into action early. Chicago’s bullpen has a 3.62 ERA, while Boston’s pen has managed a 3.55 ERA.

The Over has hit in the past 2 games for the Red Sox, allowing 13 runs in the outings.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Chicago Cubs at Boston Red Sox odds, picks and predictions

Analyzing Friday’s Chicago Cubs at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (16-9) and Boston Red Sox (14-12) open a 3-game interleague series Friday at Fenway Park. First pitch is scheduled for 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Red Sox won 2-1 in 2023 at Wrigley Field

The Cubs posted a 3-game interleague series sweep of the Houston Astros earlier this week, outscoring the ‘Stros 14-6 while cashing the Under in all 3 outings. The Cubs have won 5 consecutive interleague games. The total has gone low in 5 of the past 6 outings, and the Under is 10-3 in the past 13 games.

The Red Sox dropped 2 of 3 games on the road against the Cleveland Guardians, while the Under is on a 4-1-1 run for Boston. At home, Boston is just 3-7 this season. In interleague play, Boston is 3-for-3 this season after sweeping the Pittsburgh Pirates on the road April 19-21.

Cubs at Red Sox projected starters

LHP Shota Imanaga vs. RHP Kutter Crawford

Imanaga (3-0, 0.84 ERA) makes his 5th start of the season. He has a 0.75 WHIP, 0.8 BB/9 and 8.9 K/9 in 21 1/3 IP.

  • Last start: Win, 6 IP, 3 R (2 ER), 5 H (1 HR), 0 BB, 5 K in 5-3 home win Saturday vs. Miami Marlins
  • 2024 road splits: Win, 5 1/3 IP, 1 R (0 ER), 5 H, 2 BB, 4 K in 4-1 win vs. Seattle Mariners on April 13 in his only road appearance to date

Crawford (1-0, 0.66 ERA) makes his 6th start. He has a 0.99 WHIP, 3.6 BB/9 and 9.9 K/9 in 27 1/3 IP.

  • Last start: Win, 6 IP, 1 ER, 7 H, 3 BB, 6 K in 4-2 road win vs. Pittsburgh Pirates last Saturday
  • 2024 home splits: 0-0, 0.00 ERA, 4 H, 4 BB, 12 K in 10 2/3 IP in 2 starts

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Cubs at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:04 a.m. ET.

  • Moneyline (ML): Cubs -110 (bet $110 to win $100) | Red Sox -110 (bet $110 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+155) | Red Sox +1.5 (-190)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Cubs at Red Sox picks and predictions

Prediction

Red Sox 3, Cubs 2

Moneyline

The RED SOX (-110) are a strong play in this interleague series opener against the Cubs (-110).

This should be a well-pitched game, and you’ll want to go lightly, as runs should be at a premium in a low-scoring pitcher’s duel. Back Boston, but have some patience, as things could get dicey.

Run line/Against the spread

The Red Sox +1.5 (-190) will set you back nearly 2 times your potential return, and that’s just too much risk for not enough reward. Over the long term, making bets with such tremendous risk will not pay off.

AVOID.

Over/Under

UNDER 8 (-105) is a slam-dunk play in this interleague series opener.

Imanaga and Crawford have each pitched amazingly well to date, with both pitchers posting sub-1.00 ERAs to this point.

Runs should be at a premium at Fenway Park, and winds will be blowing from 8-11 mph from right field to left field, somewhat limiting the potential of balls to the power alleys.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Additional MLB coverage:
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