Chicago Cubs at St. Louis Cardinals odds, picks and predictions

Analyzing Sunday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (27-25) take on the St. Louis Cardinals (24-26) Sunday in the finale of a 3-game set on Sunday Night Baseball at Busch Stadium at 7 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: Cards lead 1-0

After Friday’s game was washed out, the Cubs fell 7-6 in Saturday’s affair. It was a 3-3 game before the Cards scored 4 in the bottom of the 8th to go up 7-4. The Cubs fought back, scoring 2 in the 9th but couldn’t seal the deal. 2B Nico Hoerner had 2 hits and 2 RBIs. The Cubs have lost 3 straight and are 3-7 over the last 10.

The Cardinals have won 4 straight and 9 of 11. They sit 2 games behind the Cubs for 2nd place and 5½ out of the NL Central lead. Their top 6 hitters each had a hit Saturday, and 5 of the 6 had multiple hits. After dwelling near the bottom of baseball for much of the season, their offense has climbed to 25th with 3.9 runs per game.

Cubs at Cardinals projected starters

RHP Javier Assad vs. RHP Sonny Gray

Assad (4-0, 1.70 ERA) makes his 11th start. He has a 1.11 WHIP, 3.4 BB/9 and 7.8 K/9 in 53 innings.

  • Last start: No-decision, 4 2/3 IP, 2 ER, 4 H, 5 BB, 4 K Tuesday against the Atlanta Braves
  • 1 career start vs. St. Louis: No-decision, 4 IP, 0 ER, 4 H, 4 BB, 3 K Aug. 23, 2022

Gray (6-2, 2.87 ERA) makes his 9th start. He has a 1.04 WHIP, 1.9 BB/9 and 11.3 K/9 in 47 innings.

  • Last start: Win, 5 2/3 IP, 1 ER, 3 H, 2 BB, 6 K Monday against Baltimore Orioles
  • Last 5 starts vs. Cubs: 1-1, 3.20 ERA, 0.99 WHIP, 40 K in 25 1/3 IP

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Cubs at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:03 p.m. ET.

  • Moneyline (ML): Cubs +120 (bet $100 to win $120) | Cardinals -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-165) | Cardinals -1.5 (+140)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Cubs at Cardinals picks and predictions

Prediction

Cubs 4, Cardinals 3

Moneyline

This game is in jeopardy because there have been severe storms in the St. Louis area Sunday morning, and there are more expected in the evening. So keep that in mind if you’re using a boost or a promo that you wouldn’t ordinarily have returned if the game were to be rained out.

The Cards used their top 3 relievers Saturday night, which puts them in limbo Sunday. Facing a starter the likes of Assad, their -145 ML feels inflated. It’s more of a pick ’em to me, and for the value, I’ll take CUBS (+120).

Run line/Against the spread

I like SONNY GRAY UNDER 6.5 K’S (-145) here. He has had 7+ K’s in just 3 of 8 starts. With the threat of rain, and the potential for the game to either end early or his outing to become abbreviated, the upside is on the Under here.

Over/Under

It’s slated to be 81 degrees with a 10-mph wind blowing out to left-center. The Cards are 9-1 O/U in the last 10, and they’ve averaged 6 runs per game through that stretch. So there’s definite Over momentum here. However, with the pitching acumen on the mound, and the real threat of rain, LEAN UNDER 8 (-105).

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Chicago Cubs at St. Louis Cardinals odds, picks and predictions

Analyzing Saturday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (23-26) welcome the Chicago Cubs (27-24) to Busch Stadium Saturday. First pitch to kick off the series is set for 7:15 p.m. ET (FOX). Let’s analyze FanDuel Sportsbook’s lines around the Cubs vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting of 2024, Friday’s game was postponed

The Cubs-Cardinals game, which was rained out on Friday, has been rescheduled for July 13.

Chicago is coming off a 3-0 loss to the Atlanta Braves Thursday, closing as a -117 favorite. The Cubs have lost 2 straight and 5 of their last 7. Chicago is just 3-7 over its last 10. It sits 2nd in the NL Central and has a 25-26 against the spread (ATS) record.

The Cardinals completed a rare home sweep and beat the Baltimore Orioles, one of the best teams in the MLB, in 3 straight at home. They won 5-4 in the series finale Wednesday, closing as a +124 underdog. St. Louis has won 5 of its last 6 and 8 of its last 10. It is 25-24 ATS on the season.

Cubs at Cardinals projected starters

RHP Jameson Taillon vs. RHP Miles Mikolas

Taillon (3-2, 2.20 ERA) makes his 7th start. He has a 1.19 WHIP, 2.8 BB/9 and 6.1 K/9 through 32 2/3 IP.

  • Last start: Loss, 4 2/3 IP, 3 ER, 6 H, 2 BB, 4 K in 3-2 home loss to the Pittsburgh Pirates Sunday
  • 2024 road splits: 0-1, 2.38 ERA (11 1/3 IP, 3 ER), 11 H, 3 HR, 4 BB, 3 K in 2 starts
  • Career vs. Cardinals: 5-1, 3.28 ERA (68 2/3 IP, 25 ER), 1.12 WHIP, 8.7 K/9 in 12 starts

Mikolas (3-5, 5.77 ERA) makes his 11th start. He has a 1.40 WHIP, 1.9 BB/9 and 6.6 K/9 through 53 IP.

  • Last start: Win, 5 IP, 1 ER, 2 H, 1 BB, 4 K in 7-2 home win over the Boston Red Sox last Saturday
  • 2024 home splits: 0-2, 6.20 ERA (20 1/3 IP, 14 ER), 26 H, 5 HR, 3 BB, 24 K in 6 starts
  • Career vs. Cubs: 5-4, 2.58 ERA (97 2/3 IP, 28 ER), 1.21 WHIP, 6.6 K/9 in 17 starts and 2 relief appearances

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Cubs at Cardinals odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:40 a.m. ET.

  • Moneyline (ML): Cubs -106 (bet $106 to win $100) | Cardinals -110 (bet $110 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+155) | Cardinals +1.5 (-188)
  • Over/Under (O/U): 8.5 (O: -112 | U: -108)

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Cubs at Cardinals picks and predictions

Prediction

Cubs 5, Cardinals 3

Moneyline

BET CUBS (-106).

The Cubs have struggled as of late, but they have held their opponent to 3 or fewer in 4 of Taillon’s last 6 starts. Chicago has won 4 of his 6 starts and has only lost to the Braves and Pittsburgh with the latter being a 3-2 loss. The Cubs are also the 4th-best team in the MLB following a loss with a 16-7 record.

Meanwhile, despite sweeping the Orioles at home, the Cardinals are still just 11-12 at Busch Stadium. Given the pitching disadvantages and home-field struggles, avoid the Cardinals here and back CUBS (-106).

Run line/Against the spread

PASS.

While this is enticing with the Cubs as a run-line favorite, the odds just pose better value on the moneyline. For the Cardinals, they are far too expensive, almost 2x your potential return here, as a run line underdog and are certainly not worth any wager.

Over/Under

LEAN UNDER 8.5 (-108).

The Cubs are 2-4 O/U in Taillon’s 6 starts this season. They have gone Under in 4 of their last 5 as well, scoring 4 or fewer in 7 straight games. Chicago is 21-28-2 O/U. The Cardinals are the opposite and have been red-hot.

Despite going over in 5 of their last 6, the Cardinals are still 23-24-2 O/U. They are 3-7 O/U in Mikolas’ 10 starts. Considering the trends for both starting pitchers, back UNDER 8.5 (-108).

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Chicago Cubs at St. Louis Cardinals odds, picks and predictions

Analyzing Friday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (27-24) take on the St. Louis Cardinals (23-26) Friday in the opener of a 3-game set at Busch Stadium at 8:15 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Cubs won 8-5 last year

One of the best rivalries in baseball is renewed Friday, and if you’re in the St. Louis area, Bally Sports Midwest has a treat in store. Chip Caray and Joe Buck will be on the call for 1 night only. Caray is the grandson of legendary Cubs and Cardinals announcer Harry Caray, and Buck is the son of legendary Cardinals announcer Jack Buck.

The Cubs limp into town just 3-7 over their last 10 as they completed a 2-5 homestand. They’ve scored just 23 runs in the last 10 games. One thing they have in their corner, though, is the MLB ERA leader Shota Imanaga on the hill.

The Cards are coming off their most optimistic series in a couple of years as they completed a 3-game sweep of the Baltimore Orioles. They are 8-2 over their last 10 to climb within 5 games of the NL Central lead. SS Masyn Winn is a budding star as the rookie is hitting .295 with 2 homers, 15 RBIs and 7 steals while playing electric defense. He has a 2.0 WAR on the young season.

Cubs at Cardinals projected starters

LHP Shota Imanaga vs. RHP Miles Mikolas

Imanaga (5-0, 0.84 ERA) makes his 10th start. He has a 0.91 WHIP, 1.5 BB/9 and 9.7 K/9 in 52 2/3 innings.

  • Last start: No-decision, 7 IP, 0 ER, 4 H, 1 BB, 7 K Saturday against Pittsburgh Pirates
  • Locates his 92-mph 4-seam heater well; opposing hitters have just a .164 BA against it, while he has thrown it 58.2% of the time
  • Has not faced Cardinals before

Mikolas (3-5, 5.77 ERA) makes his 11th start. He has a 1.40 WHIP, 1.9 BB/9 and 6.6 K/9 in 53 innings.

  • Last start: No-decision, 5 IP, 1 ER, 2 H, 1 BB, 4 K Saturday against Boston Red Sox
  • Last 5 starts vs. Cubs: 1-2, 3.65 ERA, 1.18 WHIP, 17 K in 24 2/3 IP

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Cubs at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:07 a.m. ET.

  • Moneyline (ML): Cubs -140 (bet $140 to win $110) | Cardinals +115 (bet $100 to win $115)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+125) | Cardinals +1.5 (-155)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Cubs at Cardinals picks and predictions

Prediction

Cubs 5, Cardinals 3

Moneyline

Mikolas is not the same pitcher after the league abolished defensive shifting. He was an All-Star in 2022, but he allowed a league-high 226 hits last year and has allowed 63 in 53 IP this year. The Cards are on fire, but they generally struggle against pitchers they haven’t seen before. And Imanaga has the entire league off balance.

I’ll take the CUBS -140.

Run line/Against the spread

Imanaga has 7+ K’s in 5 straight starts. The Cards are a little whiff-heavy at 13th-easiest to fan at 8.53 K’s per game. The Cards don’t have a lot of right-handed-hitting depth, and we’ll see some lefty-on-lefty action. Lefties are striking out at a 28% clip against Imanaga this season.

Take SHOTA IMANAGA OVER 5.5 K’S (-110).

Over/Under

It’s slated to be a humid, 78-degree evening with the wind blowing out to left-center at 7 mph. The Cubs are just 3-7 O/U in their last 10 with their struggles at the plate. The Cards are 8-2 with their resurgence at the plate.

This is a tricky total because of Imanaga’s dominance. You could need the Cubs to score 6+ to cash an Over. But Mikolas has allowed at least 3 ER in 6 of his 10 starts. So that’s a good starting point to cash the OVER 7.5 (-115).

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Chicago Cubs at St. Louis Cardinals odds, picks and predictions

Analyzing Sunday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Chicago Cubs (53-51) and St. Louis Cardinals (46-60) meet Sunday for the finale of a 4-game NL Central set in St. Louis. First pitch at Busch Stadium is slated for 2:15 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: Cubs lead 8-4

The Cubs head into this game seeking a 4-game sweep. They’ve outscored the Redbirds 15-6 in the series and have won 8 consecutive games since July 21. Over that stretch, the Cubs offense has 13 HRs and as many stolen bases while averaging 6.75 runs per game.

The Cardinals visited Wrigley Field for a 4-game series last weekend and dropped 3 of 4. They won the opener in that set, so they’ve dropped 6 in a row to the Cubs since.

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Cubs at Cardinals projected starters

RHP Kyle Hendricks vs. LHP Steven Matz

Hendricks (4-4, 3.45 ERA) is making his 13th start of the 2023 season. He has a 1.04 WHIP, 1.4 BB/9 and 5.9 K/9 in 70 1/3 innings.

  • Last start: Win, 6 1/3 IP, 4 H, 3 R, 1 BB, 4 K in 7-3 win over Chicago White Sox Tuesday
  • 2023 road stats: 3-1, 2.82 ERA in 38 1/3 IP
  • Last 5 vs. Cardinals: 4-0. 1.93 ERA in 32 2/3 IP (2021-22)

Matz (1-7, 4.34 ERA) makes his 15th start. He has a 1.44 WHIP, 3.1 BB/9 and 8.8 K/9 in 87 IP in 22 games (14 starts).

  • Last start: No-decision, 6 IP, 5 H, 0 R, 1 BB, 6 K in 3-1 loss at Arizona Diamondbacks Tuesday
  • 2023 home stats: 0-4, 3.89 ERA in 41 2/3
  • Career vs. Cubs: 1-2, 4.03 ERA in 22 1/3 IP (4 starts)
  • Owns a 2.74 ERA, 1.00 WHIP across his last 23 IP

Cubs at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:37 a.m. ET.

  • Moneyline: Cubs +115 (bet $100 to win $115) | Cardinals -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-175) | Cardinals -1.5 (+145)
  • Over/Under (O/U): 9 (O: -120 | U: +100)

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Cubs at Cardinals picks and predictions

Prediction

Cardinals 5, Cubs 4

Moneyline

This summer, the NL Central looks like a revolving door with some of the best intermediate-term overall team opportunities, 2-to-3-week stretches where a team is just a solid overall fade or play nearly every day.

An overcooked Cincinnati Reds team was the 1st club through that door. A June surge was not substantiated by support figures, and the Reds became a team to bet against. Analytic real-vs.-expected bettors were rewarded with a July slide. The Cubs and their scoring profile — scoring more than they allowed — were a different kind of opportunity when the scuffled late in the 1st half and were somehow 7 games under-.500 (38-45) on July 3. They have been a solid bet-for in the 2nd half, where so far they are 11-4.

The tricky thing about this game is that the Cardinals may well be the 3rd NL Central team to go through that door. The Cards allow too many runs and are not worthy of a .500 record, but their current mark is off a few beats compared to the club averaging 4.72 RPG while allowing 5.00. Look for some St. Louis bounce-back this August, especially in games where pitching value is in the Cards’ column.

Add some pitching leverage (playing Matz, fading Hendricks, and favoring a St. Louis bullpen that has been undone by a .321 batting average on balls in play) and an early line move in overreach territory, and Sunday’s contest has value on the home side.

BACK THE CARDINALS (-135).

Run line/Against the spread

Avoid the extra juice here. PASS.

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Over/Under

The 2 starts bring in some marginal-rate figures (home runs to fly balls, averages on balls in play, clutch situational “luck”) that swing both ways — favoring Matz/St. Louis and chipping away at Hendricks/Chicago.

That calls for a meet in the middle and PASS.

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Chicago Cubs at St. Louis Cardinals odds, picks and predictions

Analyzing Friday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Chicago Cubs (51-51) and St. Louis Cardinals (46-58) meet Friday for the 2nd contest of a 4-game series in St. Louis. First pitch at Busch Stadium is slated for 8:15 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: Cubs lead 6-4

The Cubs won Thursday’s lid-lifter 10-3. They have won 6 in a row and 8 of their last 9.

St. Louis is 2-2 in its last 4, taking 2 of 3 at the Arizona Diamondbacks in the middle of the week. Prior to that series, the Cardinals visited Wrigley Field for a 4-game set. They won the opener, but dropped the final 3 games. So, they have now lost 4 in a row to the rival Cubs.

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Cubs at Cardinals projected starters

TBD vs. LHP Jordan Montgomery

Reports have Cubs RHP Hayden Wesneski (2-3, 4.75 ERA) getting called up from Triple-A Iowa to make his 11th start with the big club this season. He owns a 1.20 WHIP, 2.2 BB/9 and 7.3 K/9 in 60 2/3 innings across 15 appearances.

  • Last pitched for Cubs July 2, working 2 scoreless relief innings; optioned 2 days later to Iowa where he logged a 1.64 ERA, 1.09 WHIP in 11 IP after being sent down
  • 2023 MLB road stats: 1-2, 5.52 ERA (31 IP, 19 ER) in 7 games (6 starts)
  • Career vs. Cardinals: Pitched 2/3 innings June 25, marking his only appearance against the Redbirds (0 ER, 1 H, 1 BB 2 K)

Montgomery (6-8, 3.37 ERA) makes his 21st start. He has a 1.23 WHIP, 2.4 BB/9 and 8.2 K/9 through 115 innings.

  • Last start: Loss, 6 IP, 7 R (5 ER), 6 H, 2 BB, 4 K in 7-2 loss at Cubs Sunday
  • 2023 home stats: 4-3, 3.39 ERA (58 1/3 IP, 22 ER) in 10 starts
  • Last 5 vs. Cubs: 3-2, 3.00 ERA (2022-23)
  • Clocked 1.17 ERA across 5 starts prior to his last (June 20-July 18)

Cubs at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:16 p.m. ET.

  • Moneyline: Cubs +120 (bet $100 to win $120) | Cardinals -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-160) | Cardinals -1.5 (+135)
  • Over/Under (O/U): 9 (O: -120 | U: +100)

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Cubs at Cardinals picks and predictions

Prediction

Cubs 6, Cardinals 5

Moneyline

At 4.96 runs per game and 4.42 run per game allowed, the Cubs are deserving of a better record. Friday’s mound matchup does not put the Cubs’ best foot forward, but Wesneski may be a tad overlooked.

Montgomery figures to be slightly overrated, based both on his season line and in recent turns (.234 batting average on balls in play has buoyed a July ERA of 2.74). Expected-ERA figures peg the southpaw as being due some regression.

While BetMGM offers a Cubs (+120) ML line, look to FanDuel Sportsbook to BET CUBS (+130) at a tag with better leverage.

Run line/Against the spread

Avoid the extra juice here. PASS.

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Over/Under

The Montgomery fade and Cubs starter situation makes for an OVER 9 (-120) play. Mix in 2 second-division bullpens, some potential fatigue at the back end of the Cubs ‘pen, and a sultry St. Louis evening with an outward breeze in the forecast.

BET OVER 9 (-120).

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Chicago Cubs at St. Louis Cardinals odds, picks and predictions

Analyzing Thursday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Chicago Cubs (50-51) and St. Louis Cardinals (46-57) tangle in the Thursday opener of a 4-game series in St. Louis. First pitch at Busch Stadium is slated for 7:45 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Cubs vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: Cubs lead 5-4

Chicago is coming off a 2-game sweep of its South Side neighbors, the Chicago White Sox. The Cubs have won 5 in a row and 7 of their last 8. Over that stretch, they have cranked out a .920 OPS. The Cubs are 6 games out of the lead in the NL Central and 4 1/2 games back in the Wild-Card race.

The Cardinals are back at home after a 3-4 road trip. That trip opened with St. Louis dropping 3 of 4 to the Cubs July 20-23.

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Cubs at Cardinals projected starters

LHP Justin Steele vs. RHP Miles Mikolas

Steele (10-3, 2.95 ERA) is tabbed for his 19th start. He has logged a 1.11 WHIP, 1.8 BB/9 and 8.3 K/9 in 103 2/3 innings.

  • Last start: W, 6 1/3 IP, 2 ER, 6 H, 1 BB, 9 K in 4-3 win vs. Cardinals Friday
  • 2023 road stats: 3-1, 2.93 ERA in 7 starts (.650 OPS allowed)
  • Last 5 vs. Cardinals: 3-1, 3.86 ERA (2021-23)
  • Has yielded more than 2 runs in just 2 of his last 7 starts

Mikolas (6-5, 4.33 ERA) is making his 23rd start of the season. He has a 1.31 WHIP, 1.8 BB/9 and 6.1 K/9 in 126 2/3 innings.

  • Last start: No-decision, 5 IP, 5 ER, 11 H, 1 BB, 3 K in 8-6 loss at Cubs Saturday
  • 2023 home stats: 2-2, 4.95 ERA in 56 1/3 IP
  • Last 5 vs. Cubs: 1-1, 3.56 ERA (2022-23)
  • Owns a 4.89 ERA since June 16

Cubs at Cardinals odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:51 a.m. ET.

  • Moneyline: Cubs +102 (bet $100 to win $102) | Cardinals -118 (bet $118 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-210) | Cardinals -1.5 (+172)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Cubs at Cardinals picks and predictions

Prediction

Cubs 5, Cardinals 4

Moneyline

Steele has been a favorite of -127 or better in each of his last 5 starts. He owns a 3.52 ERA over his last 5 starts and that’s with a .341 batting average on balls in play. Over the last 2 seasons, has been quite sharp in the back half of consecutive games against the same foe.

The Cubs’ won-loss record does not compute. At 4.91 runs per game and 4.44 RPG allowed, they figure as due for a good 2d half (and are off to one).

The Cubs are 5-1 in their last 6 road-series openers. BACK CHICAGO (+102).

Run line/Against the spread

In winning 7 of their last 8, the Cubs have won by multiple runs 6 times. But PASS on the current tag.

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Over/Under

Criss-crossing signals here, and there’s no value in playing a small edge either way. PASS.

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Chicago Cubs vs. St. Louis Cardinals odds, picks and predictions

Analyzing Sunday’s Chicago Cubs vs. St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

The Chicago Cubs (37-38) and the St. Louis Cardinals (31-45) will conclude their 2-game series at London Stadium on Sunday. First pitch is scheduled for 10 a.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 2-2

The Cubs beat the Cardinals 9-1 on Saturday, with OF Ian Happ supplying 2 HRs. Chicago extended its winning streak to 4 games on Saturday and it has won 9 of its last 10 contests. The Cubs are 3 games behind the 1st-place Cincinnati Reds in the NL Central.

It was another rough outing for RHP Adam Wainwright on Saturday. He allowed 7 ER on 11 H with 1 BB and 0 K in 3 IP. St. Louis has gone 4-6 in its last 10 games and remains at the bottom of the NL Central.

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Cubs vs. Cardinals projected starters

RHP Marcus Stroman vs. LHP Matthew Liberatore

Stroman (9-4, 2.28 ERA) makes his 17th start. He has a 1.02 WHIP, 3.1 BB/9 and 7.6 K/9 in 98 2/3 innings.

  • Has been credited with a win in 7 straight starts
  • May 8 vs. Cardinals: 6 IP, 4 H, 2 ER, 1BB, 6 K and the loss in a 3-1 St. Louis win

Liberatore (1-2, 6.12 ERA) makes his 6th start. He has a 1.56 WHIP, 4.3 BB/9 and 6.5 K/9 in 25 innings.

  • Has walked 2 or more batters in all 5 starts
  • Last win was May 17 vs. Milwaukee Brewers

Cubs vs. Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1 a.m. ET.

  • Moneyline (ML): Cubs -150 (bet $150 to win $100) | Cardinals +125 (bet $100 to win $125)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (-105) | Cardinals +1.5 (-115)
  • Over/Under (O/U): 11.5 (O: +100 | U: -120)

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Cubs vs. Cardinals picks and predictions

Prediction

Cubs 7, Cardinals 3

Moneyline

Stroman has been one of the best pitchers in baseball this season, so I’ll back the CUBS (-140) in Sunday’s divisional matchup. Chicago is also one of the hottest teams in baseball, while St. Louis has been largely disappointing.

Run line/Against the spread

CUBS -1.5 (-105) is an enticing bet with how these teams have performed recently. Chicago is also tied for the 7th-best ISO (.179), the 5th-best wOBA (.339), and the 6th-best wRC+ against left-handed pitching this season.

The Cubs have also outscored their opponents 29-4 amid their current 4-game winning streak.

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Over/Under

UNDER 11.5 (-120) is the lean in this game despite London Stadium being viewed as a hitter-friendly park. Stroman has been lights out this season, and even with Wainwright giving up 7 runs himself on Saturday, there were still fewer than 12 runs scored.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Chicago Cubs vs. St. Louis Cardinals odds, picks and predictions

Analyzing Saturday’s Chicago Cubs vs. St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

The Chicago Cubs (36-38) and the St. Louis Cardinals (31-44) start a 2-game series Saturday in London with the Cardinals serving as the home team. First pitch from London Stadium is set for 1:10 ET (FOX). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: St. Louis leads 2-1

The NL Central has been a buzz this season. After the Pittsburgh Pirates’ early success, the Cincinnati Reds caught fire and jumped into 1st place — behind a 12-game win streak entering Saturday. The Cubs have been hot as well, winning 10 of their last 12 to get withing 2 games of .500.

The Cardinals have received attention this season but for the wrong reasons. They are last in the division one year after winning it. But Cards-Cubs is still a stellar rivalry that MLB is bringing to England.

St. Louis is coming off a 3-0 loss as a -152 road favorite to the lowly Washington Nationals Wednesday — the shutout snapped a Cardinals’ 4-game win streak, though they’re 4-7 in their last 11 games.

The Cubs are coming off a 3-game sweep of the Pirates, capped by an 8-3 victory as slight -112 road favorites Wednesday.

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Cubs vs. Cardinals projected starters

LHP Justin Steele vs. RHP Adam Wainwright

Steele (7-2, 2.71 ERA) makes his 14th start of the season. He has a 1.07 WHIP, 2.1 BB/9 and 7.6 K/9 in 73 innings.

  • Last start: Win, 5 IP, 2 ER, 5 H, 1 BB, 4 K in 3-2 home victory vs. Baltimore Orioles last Saturday
  • Only allowed 3 homers this season
  • Career vs. Cardinals: 1-1, 5.00 ERA (18 IP, 10 ER), 1.61 WHIP, 4.5 K/9 in 3 starts, including 10-4 home victory in his only start vs. Cards this season (6 IP, 3 ER, 7 H, 3 BB, 3 K)

Wainwright (3-1, 5.56 ERA) makes his 9th start. He has a 1.67 WHIP, 2.7 BB/9 and 4.9 K/9 in 43 2/3 innings.

  • Last start: Win, 6 1/3 IP, 3 ER, 7 H, 2 BB, 3 K in 5-3 road win vs. the New York Mets last Saturday
  • Whether pitching at home or on road, Wainwright allows .323 batting average
  • Career vs. Cubs (regular season): 19-14, 3.84 ERA (302 1/3 IP, 129 ER), 1.29 WHIP, 7.5 K/9 in 57 games (48 starts)
  • 2022 vs. Cubs: 2-1, 2.88 ERA (25 IP, 8 ER), 1.48 WHIP, 3.2 K/9 in 4 starts

Cubs vs. Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:07 a.m. ET.

  • Moneyline (ML): Cubs -135 (bet $135 to win $100) | Cardinals +110 (bet $100 to win $110)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+105) | Cardinals +1.5 (-125)
  • Over/Under (O/U): 14 (O: -105 | U: -115)

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Cubs vs. Cardinals picks and predictions

Prediction

Cubs 6, Cardinals 5

Moneyline

BET CUBS (-135).

The Cubs’ bats showed up in their recent 3-game sweep at the Pirates, totaling 20 runs. Plus, the pitching staff tossed 2 shutouts.

Chicago is cookin’ on both sides of the ball. Expect it to continue Saturday across the pond vs. struggling St. Louis.

Run line/Against the spread

Just because the Cubs are the better team on paper doesn’t mean the Cardinals won’t keep it close. St. Louis is one of the better teams as an underdog, posting a 19-10 ATS record.

Since I’m backing the Cubs moneyline, I will PASS on the spread.

But if interested in a 9-to-1 payoff, consider grabbing CUBS TO WIN BY 1 RUN (+900) for a small wager.

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Over/Under

Both teams on the road tend to cash Under tickets.

The Under is 20-17 for the Cubs when they’re away from the friendly confines, while the Under is 24-16-1 for the Cardinals away from Busch Stadium.

On top of that, the Under is 6-1 for the Cubs in their last 7 games against sub-.500 teams.

There have been just 2 MLB games in London in the past when the New York Yankees swept the Boston Red Sox in 2019. Both contests were high-scoring as New York claimed 17-13 and 12-8 victories.

Some sportsbooks have slightly juiced the Under for Saturday’s Cubs-Cardinals matchup — FanDuel Sportsbook has an Under of 13.5 posted with -115 juice.

BET UNDER 14 (-115) at BetMGM Sportsbook.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Ethan Matthew on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
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Chicago Cubs at St. Louis Cardinals odds, picks and predictions

Analyzing Sunday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Chicago Cubs (56-77) visit the St. Louis Cardinals (78-55) to finish their 3-game series Sunday at Busch Stadium. First pitch is 2:15 pm. Let’s analyze Tipico Sportsbook‘s lines around the Cubs vs. Cardinals odds with MLB picks and predictions.

Season series: St. Louis leads 12-6

After the Chicago Cubs took a 3-run lead in the 1st inning of Saturday’s game, the St. Louis Cardinals responded almost immediately. They scored 2 in the bottom of the 1st and then 6 in the 3rd to win 8-4. Cardinals 1B Paul Goldschmidt hit his 34th HR in the victory.

The Cubs have lost 6 of their last 7 games and look to prevent a sweep Sunday.

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Cubs at Cardinals projected starters

RHP Marcus Stroman vs. RHP Miles Mikolas

Stroman (3-6, 3.98 ERA) makes his 20th start. He has a 1.21 WHIP, 2.6 BB/9 and 7.5 K/9 through 101 2/3 IP.

  • Is 3-2 with a 2.05 ERA, 1.03 WHIP and .219 opponent batting average over 11 away games
  • Last start: No Decision, 5 IP, 1 ER, 3 H, 2 BB and 1K in a loss at the Toronto Blue Jays Tuesday

Mikolas (10-10, 3.48 ERA) makes his 28th start. He has a 1.04 WHIP, 1.6 BB/9 and 6.6 K/9 through 168 1/3 IP.

  • Is 5-2 with a 2.45 ERA, 0.84 WHIP and .198 opponent batting average across 12 home starts
  • Last start against the Cubs: 6 2/3 IP, 3 ER, 6 H, 1 BB and 3 K in a 7-1 road loss Aug. 24th

Cubs at Cardinals nickname odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:13 a.m. ET.

  • Money line (ML): Cubs +155 (bet $100 to win $155) | Cardinals -190 (bet $190 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-140) | Cardinals -1.5 (+115)
  • Over/Under (O/U): 7.5 (O: +100 | U: -125)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Cubs at Cardinals nickname picks and predictions

Prediction

Cardinals 6, Cubs 3

Money line

The last time the Cubs were swept it was at the hands of the Cardinals in early August, and history should repeat itself. The lines are too juiced to pick St. Louis so it’s best to AVOID.

Run line/Against the spread

St. Louis is 25-18 ATS as a home favorite, the 2nd-best record in baseball.

The Cubs cover 46.7% (35-40) of the time after a loss.

LEAN CARDINALS -1.5 (+115).

Over/Under

Recent trends point to both teams hitting the Over in game 3 of a series.

It’s 8-1 in the last 9 game 3s for the Cardinals; it’s 3-1 in the last 4 game 3s for the Cubs.

The Cubs have also gone Over in 4 of their past 6 overall while the Cardinals went Over in 5 of their last 6 home games.

BET OVER 7.5 (+100).

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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Chicago Cubs at St. Louis Cardinals odds, picks and predictions

Analyzing Friday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Chicago Cubs (56-75) and the St. Louis Cardinals (76-55) begin a 3-game series Friday. First pitch from Busch Stadium is at 8:15 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cubs vs. Cardinals odds with MLB picks and predictions.

Season series: Cardinals lead 10-6

The Cubs have lost 4 of their last 5 games but they took down the Toronto Blue Jays 7-5 on the road in their last contest Wednesday. Chicago pitched a bullpen game Wednesday and every starter got a hit except for 3B Christopher Morel.

The Cardinals have won 6 of their last 10 contests. They outscored the Cincinnati Reds 19-12 and took 2 of 3 contests in a 3-game road series to start the week.

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Cubs at Cardinals projected starters

RHP Adrian Sampson vs. LHP Jordan Montgomery

Sampson (1-4, 3.97 ERA) makes his 13th start and 15th appearance. He has a 1.34 WHIP, 2.3 BB/9 and 6.9 K/9 through 65 2/3 IP.

  • Owns an 8.10 ERA and a .407 BABIP in his last 6 2/3 IP spanning 2 starts
  • Aug. 23 vs. St. Louis: 3 1/3 IP, 5 ER, 8 H, 0 BB, 2 HR, 0 K

Montgomery (7-3, 3.28 ERA) makes his 6th start for St. Louis and 27th start overall. He has a 1.04 WHIP, 1.7 BB/9 and 7.7 K/9 through 145 1/3 IP.

  • Has posted a 1.76 ERA and a 0.82 WHIP across his first 5 starts for the Cardinals
  • Aug. 23 at Chicago: 9 IP, 0 ER, 1 H, 0 BB, 7 K

Cubs at Cardinals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:15 a.m. ET.

  • Money line (ML): Cubs +200 (bet $100 to win $200) | Cardinals -250 (bet $250 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-108) | Cardinals -1.5 (-112)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Cubs at Cardinals picks and predictions

Prediction

Cardinals 8, Cubs 3

Money line

The Cardinals (-250) are favored for a reason in this matchup, but I’ll PASS on the money line at the current odds. You would have to place a $250 wager just to get $100 back which isn’t a good long-term strategy.

Run line/Against the spread

The run line is where I would focus my attention in this game. Being able to get the CARDINALS -1.5 (-112) at fantastic odds feels pretty generous.

If you don’t trust St. Louis to cover the spread for the entire game, you can take CARDINALS -0.5 FIRST 5 INNINGS (-150) instead. It helps that the Cardinals are 4-0 in Montgomery’s 4 home starts for the team.

Over/Under

The wind is expected to be blowing out to left field in Friday’s showdown and Sampson owns a 1.84 HR/9 against right-handed batters, so OVER 7.5 RUNS (-130) seems to be a logical bet as St. Louis has quite a few talented righties that could result in them hitting the Over themselves.

The Over is 4-0 in the last 4 home games for the Cardinals when they face a right-handed pitcher.

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Skyler Carlin on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
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BaseballPress.com: Your source for every MLB lineup

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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