Kansas City Chiefs at Arizona Cardinals odds, picks and predictions

Analyzing Saturday’s Kansas City Chiefs at Arizona Cardinals odds and lines, with expert NFL picks and predictions.

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The Kansas City Chiefs (0-1) visit the Arizona Cardinals (1-0) Saturday. Kickoff from State Farm Stadium is at 8 p.m. ET. Below, we analyze BetMGM Sportsbook’s lines around the Chiefs vs. Cardinals odds, and make our expert NFL picks and predictions.

The Chiefs opened the preseason with a 26-24 road loss vs. the New Orleans Saints Sunday. Kansas City had a 24-17 lead in the 4th quarter but gave up a touchdown with 1:20 left to allow New Orleans to get back into things. QB Chris Oldadokun tossed an interception just a few plays later that led to the Saints hitting the game-winning field goal as time expired.

The Cardinals opened the preseason at home with an 18-17 comeback win over the Denver Broncos last Friday. Arizona trailed 17-10 with 1:30 left but went on a 10-play, 75-yard drive and scored on an 18-yard touchdown pass and successful 2-point conversion with 2 seconds remaining.

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Chiefs at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 9:34 a.m. ET,

  • Moneyline (ML): Chiefs -300 (bet $300 to win $100) | Cardinals +240 (bet $100 to win $240)
  • Against the spread (ATS): Chiefs -7.5(-110) | Cardinals +7.5 (-110)
  • Over/Under (O/U): 40.5 (O: -110 | U: -110)

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Chiefs at Cardinals picks and predictions

Prediction

Cardinals 23, Chiefs 20

Moneyline

The Chiefs are expected to play their starters for around the first half, although QB Patrick Mahomes could play less than that. The Cardinals have not said how long they will play their starters.

In any case, it will be backups and NFL hopefuls deciding the outcome of the game. Preseason games are extremely unreliable and volatile for betting purposes.

The best way to bet on these preseason exhibitions is to simply play the underdog on the moneyline for the value.

BET CARDINALS (+240).

Against the spread

The Cardinals are 1-0 ATS with their preseason-opening win. The Chiefs are 0-1 ATS in the preseason with their loss.

But again, preseason games are too volatile for trend-follow bets.

PASS.

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Over/Under

Seven of the 16 preseason games last week had more than 40 total points. The Cardinals scored 18 second-half points. The Chiefs’ game had 50 total points last week.

BET OVER 40.5 (-110).

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Kansas City Chiefs at Arizona Cardinals odds, picks and prediction

Analyzing the Kansas City Chiefs at Arizona Cardinals preseason Week 2 matchup, with NFL odds, lines, picks, predictions and best bets.

The Kansas City Chiefs (1-0) visit the Arizona Cardinals (1-0) Friday for an 8 p.m. ET kickoff at State Farm Stadium. Below, we look at the Chiefs vs. Cardinals odds and lines and make our best NFL picks, predictions, and bets.

The Chiefs will play their starters for about a half Friday, according to head coach Andy Reid, as QB Patrick Mahomes looks to get even more comfortable with his retooled offensive line after logging about a quarter’s worth of action against the San Francisco 49ers last week.

Arizona is expected to give QB Kyler Murray his first game action of the preseason after the star quarterback sat out the opener. The Cardinals upgraded the offense during the offseason with the additions of RB James Conner and WR A.J. Green.

Chiefs at Cardinals odds, spread, and lines

Odds via Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 4:40 p.m. ET.

  • Money line: Chiefs -190 (bet $190 to win $100) | Cardinals +155 (bet $100 to win $155)
  • Against the spread/ATS: Chiefs -3.5 (-105) | Cardinals +3.5 (-115)
  • Total: 40.5 (O: -115 | U: -105)

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Chiefs at Cardinals odds, lines, predictions and picks

Prediction

Chiefs 21, Cardinals 20

Money line

Bet on the CHIEFS (-190) Reid will have his offense on the field for the entire first half.

Mahomes should thrive behind OT Orlando Brown and G Joe Thuney during the regular season and Friday night offers the first glimpse of the retooled Kansas City offensive front.

Against the spread

PASS on the Chiefs -3.5 (-105), as Reid is only 39-39-4 ATS in the preseason.

Kansas City’s high-powered offense should get the Chiefs out to an early lead before giving way to the reserves and roster bubble guys for the second half. Arizona could make things close in the end.

Over/Under

Bet on the OVER 40.5 (-115) as both teams are capable of putting points on the board in a hurry.

For Kansas City, WR Tyreek Hill, TE Travis Kelce, RB Clyde Edwards-Helaire and the retooled offensive line will all see extended time against an Arizona defense that will be without DE J.J. Watt.

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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Kansas City Chiefs at Arizona Cardinals odds, picks and prediction: Murray vs. Mahomes on display

Looking at Friday’s Kansas City Chiefs at Arizona Cardinals NFL preseason odds and lines.

The Kansas City Chiefs (1-0) face the Arizona Cardinals (1-0) Friday at State Farm Stadium. Kickoff is scheduled for 8 p.m. ET. Below, we look at the Chiefs at Cardinals odds and lines.

The Chiefs only played their starters for a couple of series against the San Francisco 49ers in their opener as the backups rallied to score the game-winning touchdown with just over a minute remaining in a 19-16 victory. The 49ers took at 16-13 lead with 2:37 left in the fourth quarter but the Chiefs went 68 yards in nine plays in 1:23 to secure the win.

The Cardinals picked up a 19-16 preseason win at home over the Dallas Cowboys in their opener. K Matt Prater hit two field goals in the final two minutes including a 47-yarder as time expired.

Chiefs at Cardinals: Odds, spread and line

Odds via Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 8 p.m. ET.

  • Money line: Chiefs -133 (bet $133 to win $100) | Cardinals +110 (bet $100 to win $110)
  • Against the spread/ATS: Chiefs -2.5, -115 (bet $115 to win $100) | Cardinals +2.5, -105 (bet $105 to win $100)
  • Total: 41.5, Over -105 (bet $105 to win $100) | Under -115 (bet $115 to win $100)

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2020 Betting stats:

  • ATS: Chiefs 8-11 | Cardinals 7-9
  • O/U: Chiefs 9-10 | Cardinals 5-11

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The Cardinals, at +110 odds, have an implied 47.62% chance of winning, or 11/10 fractional odds. If Arizona wins outright, ties, or loses by less than a field goal a Cardinals +2.5 (-105) ATS bet wins.

The Chiefs (-133) have an implied 57.08% chance of beating the Cardinals, or 100/133 fractional odds. Kansas City must win by 3 or more points for a Chiefs -2.5 (-115) ATS ticket to cash.

There would need to be at least 42 points scored Friday for an Over 41.5 (-105) ticket to cash, while a combined point total of 41 or fewer points is a win for the Under.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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