St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Saturday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (56-54) and Chicago Cubs (54-58) play the 3rd game of a 4-game series Saturday. First pitch from Wrigley Field is set for 2:20 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 6-5

St. Louis dropped another game at Wrigley 6-3 Friday night. RHP Erick Fedde was roughed up in his debut for the Cardinals (5 IP, 5 ER, 6 H, 2 HR, 0 BB, 4 K). All 3 of the Cardinals’ runs were scored on bases-loaded walks. The Cardinals are 27-29 on the road and 56-54 against the spread (ATS).

The Cubs won their 3rd straight game Friday behind homers from C Christian Bethancourt and 1B Michael Busch in a 5-run 2nd inning. RHP Javier Assad held St. Louis to 1 earned run but only lasted 4 1/3 innings. Chicago is 29-25 at Wrigley Field and 52-60 ATS

Cardinals at Cubs projected starters

RHP Kyle Gibson vs. RHP Jameson Taillon

Gibson (7-4, 3.97 ERA) makes his 21st start. He has a 1.34 WHIP, 3.7 BB/9 and 8.1 K/9 in 113 1/3 IP.

  • Last start: Loss, 5 IP, 2 ER, 6 H, 3 BB, 0 K in 14-3 home loss against Washington Nationals July 27
  • 2024 road splits: 5-1, 3.13 ERA (60 1/3 IP, 21 ER), 1.08 WHIP, 9.5 K/9 in 10 starts
  • 2024 vs. Cubs: 1-0, 3.27 ERA (11 IP, 4 ER), 1.36 WHIP, 7.4 K/9 in 2 starts

Taillon (7-6, 3.35 ERA) makes his 19th start. He has a 1.17 WHIP, 1.9 BB/9 and 7.1 K/9 in 104 2/3 IP.

  • Last start: Loss, 4 1/3 IP, 6 ER, 6 H, 1 BB, 4 K in 7-1 road loss to Cincinnati Reds Monday
  • 2024 home splits: 5-3, 2.68 ERA (57 1/3 IP, 17 R (16 ER), 1.14 WHIP, 8.0 K/9 in 9 starts
  • 2024 vs. Cardinals: 1-1, 4.15 ERA (17 1/3 IP, 8 ER), 1.50 WHIP, 4.7 K/9 in 3 starts

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Cardinals at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:15 a.m. ET.

  • Moneyline (ML): Cardinals +100 (bet $100 to win $100) | Cubs -118 (bet $118 to win $100)
  • Run line (RL)/Against the spread: Cardinals -1.5 (+164) | Cubs +1.5 (-200)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Cardinals at Cubs picks and predictions

Prediction

Cubs 6, Cardinals 4

Moneyline

BET CUBS (-118).

All the momentum is with the Cubs right now, and I’m going to ride that into a victory Saturday. Taillon has a 2.68 ERA at home and has won 2 of his last 3 starts at Wrigley. He just beat the Cardinals at Busch Stadium July 14. Chicago’s ERA at home is also nearly a full point than its ERA in away games (3.28 vs. 4.27).

Gibson does not have a good history against Chicago with a record of 1-4 and an ERA of 5.46. He had a 3.33 ERA in May, 3.97 in June and 4.91 in July — not a good trend as he gets his 1st start of August.

Run line/Against the spread

PASS.

I’m going to keep my bet to the moneyline.

Over/Under

BET OVER 7.5 (-105).

It’s hard to ignore the trends with this one. These 2 teams have gone Over in their last 5 head-to-head meetings, including the 1st 2 games of this series. The Cardinals have also been Over in 5 straight games.

The Over has hit in 5 of Gibson’s last 6 starts, while it hit in 3 of Taillon’s last 5.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Friday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (33-34) and Chicago Cubs (33-35) begin a 3-game series Friday. First pitch from Wrigley Field is slated for 2:20 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 2-0

The Cardinals finished 4-3 in their 7-game homestand after Thursday’s 4-3 over the Pittsburgh Pirates. LF Brendan Donovan took Pirates RHP Mitch Keller deep in the 6th inning to snap the 3-all tie. St. Louis also got a 2-run HR from 1B Paul Goldschmidt. They are 16-19 away from Busch Stadium as they head off on a 6-game road trip.

The Cubs are thrilled to be heading back to Chicago after going 2-5 over their 7-game road trip. They dropped their series finale against the Tampa Bay Rays 3-2 on Thursday. Starting LHP Justin Steele was the hard-luck loser (6 IP, 0 ER, 3 H, 5 K) with the only offense coming on a fielder’s choice ground out followed by a sacrifice from C Yan Gomes.

Cardinals at Cubs projected starters

RHP Kyle Gibson vs. LHP Jordan Wicks

Gibson (4-2, 3.76 ERA) makes his 14th start. He has a 1.27 WHIP, 3.5 BB/9 and 7.9 K/9 in 76 2/3 IP.

  • Last start: No-decision, 6 IP, 3 ER, 8 H, 2 BB, 7 K in 6-5 loss against the Colorado Rockies Saturday
  • Last start vs Cubs: Loss, 6 IP, 3 ER, 3 H, 2 BB, 7 K in 3-2 road loss June 17, 2023, as a member of the Baltimore Orioles
  • Has lost all 4 of his career starts against the Cubs

Wicks (1-2, 4.44 ERA) makes his 6th start. He has a 1.48 WHIP, 3.4 BB/9 and 10.3 K/9 in 26 1/3 IP.

  • Last start: Win, 6 IP, 2 ER, 5 H, 0 BB, 4 K in 7-2 victory against the Houston Astros on April 23
  • Has never started against the Cubs
  • 2024 home splits: 1-1, 3.38 ERA (10 2/3 IP, 4 ER), 1.13 WHIP, 9.3 K/9 in 2 starts

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Cardinals at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:23 a.m. ET.

  • Moneyline (ML): Cardinals -104 (bet $104 to win $100) | Cubs -112 (bet $112 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+158) | Cubs +1.5 (-192)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Cardinals at Cubs picks and predictions

Prediction

Cubs 4, Cardinals 3

Moneyline.

BET CUBS (-104).

I like Chicago to take the opener of this series at home. The Cubs have owned Gibson and it doesn’t matter what team he’s pitching for at the time. He’s 0-4 with a 6.64 ERA against the Cubs. Gibson has also allowed at least 3 ER in both of his starts this month.

Chicago begins a 9-game homestand, which is music to their ears since they are 18-13 at Wrigley Field.

Run line/Against the spread

PASS.

I’ll save my wager for the money line in this game.

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Over/Under

BET UNDER 8 (-105)

It’s hard not to love the Under in this game with all the trends pointing you that direction. In their last 5 meetings, the Under has hit in 4 of them. The Cubs have been Under in their last 6 games and the Cardinals have been Under in their last 4.

Wicks has allowed 2 runs or fewer in 4 of his last 5 starts while Gibson has allowed a grand total of 7 ER over his last 4 starts (21 2/3 IP). This game should be low scoring.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @DrewPhelps05 on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

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