Buffalo Bills vs. New England Patriots odds lines money line against the spread Over Under

Buffalo Bills at New England Patriots odds, picks and predictions

Analyzing Thursday’s Buffalo Bills at New England Patriots odds and lines, with expert NFL picks, predictions and best bets.

The Buffalo Bills (8-3) travel to meet the New England Patriots (6-5) for Thursday Night Football in Week 13 at Gillette Stadium. Kickoff is scheduled for 8:15 p.m. ET (Prime Video). Below, we analyze Tipico Sportsbook’s lines around the Bills vs. Patriots odds, and make our expert NFL picks and predictions.

The Bills search for a 2nd consecutive Thursday victory after they hung on for a 28-25 win against the Detroit Lions on Thanksgiving Day. Buffalo has scored 23 or more points in 7 of its last 8 games.

The Under is 7-2 in the past 9 games overall for Buffalo, including 2-0 in the first 2 games against AFC East Division opponents.

The Patriots are coming off a 33-26 setback in Minnesota on Thanksgiving Night, snapping a 3-game win and cover streak. The Over cashed against the Vikings, snapping a 3-game Under run, too.

New England has posted 2 wins in 3 games against AFC East foes this season, while also going 2-1 ATS. The Under is 3-0 inside the division for the Pats, too.

FOOTBALL NEVER STOPS
Live games, analysis and more 7 days a week: Get ESPN+

Bills at Patriots odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:57 a.m. ET.

Moneyline (ML): Bills -190 (bet $190 to win $100) | Patriots +160 (bet $100 to win $160)
Against the spread: Bills -3.5 (-109) | Patriots +3.5 (-111)
Over/Under (O/U): 43.5 (O: -110 | U: -110)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Bills at Patriots key injuries

Bills

OL Dion Dawkins (ankle) out
LB Von Miller (knee) out

Patriots

C David Andrews (thigh) questionable
OL Yodny Cajuste (calf) questionable
RB Damien Harris (thigh) out
CB Marcus Jones (ankle) questionable
WR Jakobi Meyers (shoulder) questionable
CB Jalen Mills (groin) questionable
WR DeVante Parker (groin) questionable
FS Jabrill Peppers (illness) questionable
OL Isaiah Wynn (foot) out

Play our free daily Pick’em Challenge and win! Play now!

Bills at Patriots picks and predictions

Prediction

Bills 23, Patriots 18

Moneyline

The Bills (-190) are just slightly over my personal money line limit for a singular play.

The Patriots (+160) are a tempting play due to their impressive defense that allows just 307.8 total yards per game (4th) and just 18.4 points per game (6th).

This is an especially tough game for the Pats, however, facing a Buffalo offense that has posted 415.9 total yards per game (2nd), 279.2 passing yards per game (3rd) and 28.1 PPG (2nd).

PASS, and look to the spread instead.

Against the spread

Play the BILLS -3.5 (-109) lightly, laying the 3 and a hook. Buffalo is just 1-3-1 ATS in its last 5 road games, but it’s 7-3-1 ATS in the past 11 games inside the AFC East.

Buffalo is also 3-0-1 ATS in the past 4 trips to Foxboro while going 5-2-1 ATS in the past 8 meetings overall. The road team is 19-7-2 ATS in the past 28 meetings in this series, too.

Over/Under

UNDER 43.5 (-110) is the play in this primetime matchup.

We’ll have temperatures around freezing and winds 9-12 mph, but nothing either of these northern teams can’t handle. In fact, each team might find the weather rather balmy.

However, the defenses are driving the train for this Under play. The Under is 6-0 in the past 6 road games for the Bills, while going 4-1 in their last 5 against teams with winning records. The Under is also 4-0 in the past 4 Thursday appearances for the Bills — including last week against the Lions.

The Patriots have hit the Under in 5 of the past 7 against AFC foes while going 4-1 to the Under in their past 5 games following a straight-up loss.

Want action on this NFL game or any other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

[mm-video type=playlist id=01fb7dafw2b08817yr player_id=none image=https://sportsbookwire.usatoday.com/wp-content/plugins/mm-video/images/playlist-icon.png]

Follow Kevin J. Erickson on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1367]

First look: Buffalo Bills at New England Patriots odds and lines

Looking at Thursday’s Buffalo Bills at New England Patriots Week 13 NFL odds, lines and trends. Here’s what you need to know.

The Buffalo Bills (8-3) visit the AFC East rival New England Patriots (6-5) for Thursday Night Football in Week 13. Kickoff from Gillette Stadium is at 8:15 p.m. ET (Prime Video). Below, we look at Bills vs. Patriots odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

Buffalo picked up a 28-25 road victory at the Detroit Lions on Thanksgiving. QB Josh Allen had 253 passing yards with 2 TDs and 1 INT while pacing the Bills with 78 rushing yards and a score on 10 carries. WR Isaiah McKenzie led the team with 96 receiving yards on 6 receptions.

The Bills failed to cover as 10-point favorites in their 2nd straight game at Ford Field, and are 1-4 against the spread (ATS) over their last 5 games.

New England lost 33-26 at the Minnesota Vikings in the Thanksgiving nightcap. QB Mac Jones threw for a career-high 382 yards and had 2 TD against 0 INT, RB Rhamondre Stevenson had 36 yards on 7 carries as backfield mate RB Damien Harris left the game with a thigh injury.

The loss as a 2.5-point underdog ended a streak of 3 straight ATS victories.

Also see: All Week 13 odds and lines

FOOTBALL NEVER STOPS
Live games, analysis and more 7 days a week: Get ESPN+

Bills at Patriots odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:47 p.m. ET.

Moneyline (ML): Bills -220 (bet $220 to win $100) | Patriots +190 (bet $100 to win $190)
Against the spread (ATS): Bills -5 (-108) | Patriots +5 (-112)
Over/Under (O/U): 44 (O: -106 | U: -114)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

2022 betting stats

ML: Bills 8-3 | Patriots 6-5
ATS: Bills 5-5-1 | Patriots 6-4-1
O/U: Bills 3-8 | Patriots 5-6

Play our free daily Pick’em Challenge and win! Play now!

Bills vs. Patriots head-to-head

The Pats hold a 77-47-1 lead over their longtime divisional rival in a series that dates back to 1960, including a 1-1 split in the postseason. New England took 35 of 39 meetings between Dec. 17, 2000, and Dec. 21, 2019. However, Buffalo has taken 4 of the last 5 battles, including a 47-17 victory in an AFC Wild Card playoff game last season.

While the Patriots won the first regular-season contest last year, a 14-10 victory in Week 13, the Bills outscored them 80-38 over the last 2 meetings.

Buffalo holds a slight 5-4-1 ATS advantage in the last 10 head-to-head meetings, while the Over/Under has split 5-5 along that span.

Want action on this NFL game or any other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Andrew Reid on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1367]

First look: Buffalo Bills at New England Patriots odds and lines

Looking at Sunday’s Buffalo Bills at New England Patriots Week 16 NFL odds, lines and trends. Here’s what you need to know.

The AFC East race is coming down to the wire and there’s no bigger game than Sunday’s matchup between the New England Patriots (9-5) and Buffalo Bills (8-6). Kickoff will be at 1 p.m. ET Sunday afternoon at Gillette Stadium. Below, we look at the Bills vs. Patriots odds and lines; check back for our NFL picks and predictions.

The Bills snapped their two-game losing streak Sunday with a 31-14 win over the Carolina Panthers, getting back on track after losing five of their previous eight games.

Buffalo still hasn’t won back-to-back games since Week 4 and 5, but at 8-6, the Bills are still right in the thick of things in the AFC.

The Patriots fell to the Colts Saturday night, which snapped their seven-game winning streak. As 1-point underdogs, the Patriots lost 27-17, finally coming back down to earth after a remarkable stretch of wins.

New England still holds a one-game lead on Buffalo and already beat the Bills in Week 13, but a loss will complicate things in the AFC East.

Also see: All Week 16 odds and lines

Bills at Patriots odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 2:30 p.m. ET.

Money line: Bills +110 (bet $100 to win $110) | Patriots -135 (bet $135 to win $100)
Against the spread (ATS): Bills +2.5, -105 (bet $105 to win $100) | Patriots -2.5, -115 (bet $115 to win $100)
Over/Under (O/U): 43.5, O: -108 (bet $108 to win $100) | U: -112 (bet $112 to win $100)

Also see: Betting 101

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

2021 betting stats:

ML: Bills 8-6 | Patriots 9-5
ATS: Bills 7-6-1 | Patriots 9-5
O/U: Bills 7-7 | Patriots 6-8

Bills at Patriots head-to-head

The Bills and Patriots have squared off 123 times in their history, and one team has a clear edge. The Patriots are 77-45-1 all-time against the Bills and have won eight of the last 10 meetings. However, Buffalo has had the edge more recently, winning two of the last three since 2020.

These teams already squared off once in Week 13, a game the Patriots won 14-10 in bad weather conditions. But, the Bills have played the Pats tough since QB Josh Allen really took his game to the next level in 2020.

In the last 10 games between these teams, the Patriots are 6-3-1 ATS and the Over is just 4-6. The Patriots have outscored the Bills by an average of 23.4-16.1 in their last 10 games.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

Follow @camdasilva on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1367]