Baltimore Orioles at San Francisco Giants odds, picks and predictions

Analyzing Saturday’s Baltimore Orioles at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

The Baltimore Orioles (36-21) and San Francisco Giants (28-29) meet Saturday for game 2 of a 3-game series. First pitch from Oracle Park is set for 10:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 1-0

Baltimore won 3-2 as +142 underdogs in Friday’s series opener behind DH Gunnar Henderson’s go-ahead, 7th-inning solo homer. The Orioles have alternated wins and losses in their last 6 games, going 3-3.

The Giants have now dropped 3 in a row after winning the home opener of a current 6-game stand. They are still above .500 at home (16-14). However, the Orioles own a dominant 19-9 road record this season.

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Orioles at Giants projected starters

RHP Kyle Bradish vs. RHP Alex Cobb

Bradish (2-1, 3.89 ERA) makes his 10th start of 2023. He has a 1.30 WHIP, 2.9 BB/9 and 7.4 K/9 through 44 IP.

  • Last outing: No-decision, 6 2/3 IP, 1 ER, 4 H, 1 BB, 4 K in a 3-2 home win Sunday vs. Texas Rangers
  • First career start vs. San Francisco

Cobb (4-2, 3.05 ERA) makes his 12th start. He has a 1.40 WHIP, 2.6 BB/9 and 8.3 K/9 through 62 IP.

  • Last outing: Loss, 4 IP, 7 ER, 7 H, 4 BB, 5 K in a 7-5 setback Sunday at Milwaukee Brewers
  • Career vs. Baltimore: 7-2, 2.56 ERA (81 IP, 23 ER), 6 HR, 1.15 WHIP, 8.1 K/9 across 13 starts

Orioles at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:39 a.m. ET.

  • Moneyline (ML): Orioles +110 (bet $100 to win $110) | Giants -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-185) | Giants -1.5 (+150)
  • Over/Under (O/U): 8 (O: -110 | U: -110)

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Orioles at Giants picks and predictions

Prediction

Orioles 5, Giants 4

Moneyline

BET ORIOLES (+110).

Baltimore’s dominance on the road makes it the much safer bet. The underdog is 5-5 in the Orioles’ last 10 meetings overall, with Baltimore winning as the underdog in 3 of those 5 games (per TeamRankings.com).

Meanwhile, the Giants are 0-8 in their last 8 interleague home games vs. a right-handed starter, according to Covers.com.

Run line/Against the spread

PASS.

The line is simply not worth the juice for either side, bet on the moneyline and/or O/U total for this game.

Plus, we’re already invested in the Baltimore ML.

Play our free daily Pick’em Challenge and win! Play now!

Over/Under

LEAN OVER 8 (-110).

The Over is 4-0-1 in Bradish’s last 5 starts with 5 days of rest and 5-0 in Baltimore’s last 5 games vs. a starter with a WHIP of less than 1.15.

Both teams are each 5-5 O/U in their last 10 games overall.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @payton_shanks on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
BaseballHQ Fantasy Baseball
BaseballPress.com: Your source for every MLB lineup

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Baltimore Orioles at San Francisco Giants odds, picks and predictions

Analyzing Friday’s Baltimore Orioles vs. San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

The Baltimore Orioles (35-21) and San Francisco Giants (28-28) meet Friday to kick off a 3-game series. First pitch from Oracle Park is set for 10:15 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting since 2019 when Giants won series 2-1

Baltimore lost 12-8 as +104 home underdogs Wednesday vs. the Cleveland Guardians. The Orioles went 2-4 in their 6-game homestand and now begin a 6-game road stretch. The Orioles went 5-1 on their last road trip.

San Francisco lost 9-4 as -116 home favorites Wednesday vs. Pittsburgh Pirates, dropping the series 2-1. The Giants have lost 3 of their last 4 after having a 3-game win streak.

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Orioles at Giants projected starters

RHP Dean Kremer vs. RHP Logan Webb

Kremer (5-2, 4.58 ERA) makes his 12th start. He has a 1.44 WHIP, 2.6 BB/9 and 7.3 K/9 in 59 innings.

  • Last start: Loss, 6 1/3 IP, 3 ER, 5 H, 2 BB, 5 K, in a 5-3 home loss Saturday vs. Texas Rangers
  • First start vs. San Francisco

Webb (4-5, 2.75 ERA) makes his 12th start. He has a 1.07 WHIP, 1.8 BB/9 and 9.5 K/9 in 72 innings.

  • Last start: Win, 7 IP, 1 ER, 4 H, 1 BB, 11 K, in a 3-1 road win Saturday vs. Milwaukee Brewers
  • First start vs. Baltimore

Orioles at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:05 p.m. ET.

  • Moneyline (ML): Orioles +135 (bet $100 to win $135) | Giants -160 (bet $160 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-155) | Giants -1.5 (+125)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Orioles at Giants picks and predictions

Prediction

Orioles 6, Giants 4

Moneyline

LEAN ORIOLES (+135).

The Giants are mediocre at home, with a 16-13 record, while the Orioles are an exellent road team, with a 18-9 record. The Giants are 0-7 in their last 7 interleague games vs. a right-handed starter.

Run line/Against the spread

PASS.

No need to pay the juice. The moneyline offers a better value.

Play our free daily Pick’em Challenge and win! Play now!

Over/Under

LEAN OVER 8 (-105).

The Over is 3-0-1 in Baltimore’s last 4 games following a rest day and 3-0-1 in Kremer’s last 4 starts after scoring 5 runs or more in their previous game. The Giants have gone Over this total in 3 of their last 4 games.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @payton_shanks on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
BaseballHQ Fantasy Baseball
BaseballPress.com: Your source for every MLB lineup

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