Houston Astros at Cleveland Guardians odds, picks and predictions

Analyzing Saturday’s Houston Astros at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

The Houston Astros (36-28) will play the 2nd game of a 3-game series against the Cleveland Guardians (30-33) Saturday at Progressive Field. First pitch is scheduled for 6:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 1-0.

The Astros were unable to defeat the Guardians in a 10-9 loss Friday that lasted until the 14th inning. Houston has lost 4 straight games and is now 5 games back of the Texas Rangers atop the AL West.

On Friday, OF Will Brennan delivered a walk-off double in the bottom of the 14th inning to give the Guardians their 3rd consecutive win. Cleveland is 1 1/2 games behind the Minnesota Twins in the AL Central race.

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Astros at Guardians projected starters

RHP J.P. France vs. RHP Triston McKenzie

France (1-1, 3.44 ERA) makes his 7th start. He has a 1.15 WHIP, 2.4 BB/9 and 7.7 K/9 through 34 IP.

  • Has given up 4 or more ER in 2 of his first 6 starts.
  • Has surrendered at least 1 HR in 5 straight starts.

McKenzie (0-0, 0.00 ERA) makes his 2nd start. He has a 0.40 WHIP, 1.8 BB/9 and 18.0 K/9 through 5 IP.

  • Made his season debut June 4 at Minnesota Twins: 0 ER on 1 H with 1 BB and 10 K in 5 IP.
  • Boasts a 2-1 record with a 2.84 ERA, 0.84 WHIP, and 6.6 K/9 in 3 career starts against the Astros.

Astros at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:20 a.m. ET.

  • Moneyline (ML): Astros +110 (bet $100 to win $110) | Guardians -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros +1.5 (-185) | Guardians -1.5 (+150)
  • Over/Under (O/U): 7.5 (O: -120 | U: +100)

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Astros at Guardians picks and predictions

Prediction

Guardians 5, Astros 3

Moneyline

With how these teams have been playing recently, the GUARDIANS (-135) are the pick at home in Saturday’s matchup. The Astros are 0-4 in their last 4 games overall and they’ve been the road team in those 4 losses.

Run line/Against the spread

GUARDIANS -1.5 (+150) has solid value with how McKenzie looked in his 1st start of the season. France has been susceptible to the long ball in recent starts, and the Guardians are swinging hot bats right now.

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Over/Under

LEAN OVER 7.5 (-120).

Even with McKenzie on the mound for the Guardians, the Over looks like the ideal way to bet the run total in this game. Cleveland has scored 5-plus runs in 6 of its last 10 contests, including 3 games where it produced 10 or more runs.

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Houston Astros at Cleveland Guardians odds, picks and predictions

Analyzing Friday’s Houston Astros at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

The Houston Astros (36-27) begin a 3-game series against the Cleveland Guardians (29-33) on Friday at Progressive Field. First pitch is scheduled for 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting of 2023; the Astros won 4 of 7 meetings in 2022

The Astros lost 3-2 to the Toronto Blue Jays on Thursday. Houston has lost 3 consecutive games and is 5 games back of the Texas Rangers in the AL West race.

The Guardians cruised to a 10-3 victory over the Boston Red Sox Thursday. 3B Jose Ramirez led the way with 3 home runs in Thursday’s win, giving him 9 on the season. Cleveland trails the Minnesota Twins by 1 1/2 games in the AL Central.

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Astros at Guardians projected starters

RHP Cristian Javier vs. LHP Logan Allen

Javier (7-1, 2.84 ERA) makes his 13th start. He has a 0.99 WHIP, 2.1 BB/9 and 9.3 K/9 through 69 2/3 IP.

  • Has tallied 5 or more strikeouts in 10 of his first 12 outings
  • Has been credited with a win in 5 straight starts

Allen (3-2, 2.76 ERA) makes his 9th start. He has a 1.34 WHIP, 2.6 BB/9 and 9.3 K/9 through 45 2/3 IP.

  • Has notched a quality start in 4 of his first 8 turns
  • Has given up 2 or fewer ER in 6 outings

Astros at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:30 a.m. ET.

  • Moneyline (ML): Astros -115 (bet $115 to win $100) | Guardians -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (+145) | Guardians +1.5 (-175)
  • Over/Under (O/U): 8 (O: -120 | U: +100)

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Astros at Guardians picks and predictions

Prediction

Astros 4, Guardians 3

Moneyline

Even though Houston has lost 3 straight games, the ASTROS (-115) are who I’d side with in this game. Houston is 18-13 on the road compared to the Cleveland’s 14-16 record at home this season.

Run line/Against the spread

PASS.

The Guardians are capable of keeping this game close. especially after producing 19 runs in their last 3 games. That being said, taking Cleveland +1.5 (-175) to cover the run line isn’t worth the risk at the current odds.

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Over/Under

UNDER 8 (+100) is the lean in this matchup with Javier and Allen taking the mound on Friday. The Under is 4-1 in the last 5 meetings between these teams and is 5-1 in the last 6 meetings in Cleveland.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Houston Astros at Cleveland Guardians odds, picks and predictions

Analyzing Saturday’s Houston Astros at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Houston Astros (70-38) continue their road series against the Cleveland Guardians (54-52) with the 3rd game of their four-game series Saturday. First pitch is 6:10 p.m. ET at Progressive Field. Let’s analyze Tipico Sportsbook‘s lines around the Astros vs. Guardians odds with MLB picks and predictions.

Season series: Astros lead 4-1

The Astros have won 3 games in a row and 6 of their last 9. They took the first 2 games of the series 6-0 and 9-3. They can clinch a series victory with a win Saturday.

The Guardians entered this series having won 6 of 9 games but have lost twice by 6 runs. They trail the AL Central-leading Twins by 2 games.

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Astros at Guardians projected starters

RHP Luis Garcia vs. RHP Cal Quantrill

Garcia (8-7, 3.81 ERA) makes his 20th start. He has a 1.07 WHIP, 2.7 BB/9 and 9.5 K/9 through 106 1/3 IP.

  • Garcia started the only loss the Astros have had this season against the Guardians. He allowed 4 runs (2 earned) in 5 innings of a 6-1 loss.
  • His ERA is 2.72 in 9 road starts.

Quantrill (7-5, 4.08 ERA) makes his 21st start. He has a 1.32 WHIP, 2.6 BB/9 and 5.8 K/9 through 117 IP.

  • The Guardians have won his last 5 starts.
  • He has allowed 10 runs (9 earned) and 14 hits combined over his last 2 starts (11 1/3 IP).

Astros at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:15 p.m. ET.

  • Money line (ML): Astros -165 (bet $165 to win $100) | Guardians +133 (bet $100 to win $133)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (+102) | Guardians +1.5 (-125)
  • Over/Under (O/U): 8.5 (O: -115 | U: -107)

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Astros at Guardians picks and predictions

Prediction

Astros 6, Guardians 4

Money line

The Astros are 18-4 against the AL Central and 4-1 against Cleveland this season.

The Guardians are 28-29 against teams with winning records.

They have won Quantrill’s last 5 starts, but he was less effective in his last 2 outings.

Take the ASTROS (-165).

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Run line/Against the spread

The Astros are 56-52 ATS overall this season and 31-26 ATS on the road. Three of their 4 wins over the Guardians have been by more than 1 run. Nine of their last 10 wins overall have been by at least 2 runs.

The Guardians’ last 7 losses have been by more than 1 run. They are 24-25 ATS at home this season.

Take the ASTROS -1.5 (+102).

Over/Under

Three of the 5 games between these teams have had 8 or fewer runs.

Five of the last 6 games for the Astros have had fewer than 9 runs.

Meanwhile, 5 of the last 7 games for Cleveland have had 9 or more total runs.

Each of Quantrill’s last 8 starts has had totals of 9 or more runs.

Take OVER 8.5 (-115).

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Houston Astros at Cleveland Guardians odds, picks and predictions

Analyzing Thursday’s Houston Astros at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Houston Astros (68-38) take on the Cleveland Guardians (54-50) Thursday in the 1st game of a 4-game set at Progressive Field. First pitch is set for 7:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Astros vs. Guardians odds with MLB picks and predictions.

Season series: Astros lead 2-1

The Astros have hit a bit of a rough patch, going 4-6 over their last 10 games. They lost 2 of 3 to the Boston Red Sox in their last series but look to get back on track with RHP Justin Verlander on the mound. The Astros are 16-4 against the AL Central division and 34-21 on the road.

The Guardians have won 6 of their last 10 and 12 of their last 20 games as they sit just 1 game behind the division-leading Minnesota Twins. They have received a boost from 2B Andres Gimenez, who is hitting .320 with 4 extra-base hits and 4 stolen bases over the last week.

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Astros at Guardians projected starters

RHP Justin Verlander vs. RHP Zach Plesac 

Verlander (14-3, 1.81 ERA) makes his 20th start. He has a 0.87 WHIP, 1.6 BB/9 and 8.9 K/9 in 124 IP.

  • Has won his last 6 starts with a 0.86 ERA.
  • Hasn’t faced the Guardians since 2019, but he struck out 13 over 7-scoreless innings pitched in that meeting.

Plesac (2-9, 4.33 ERA) makes his 20th start. He has a 1.29 WHIP, 2.4 BB/9 and 6.8 K/9 in 104 IP.

  • He’s 0-4 with a 5.84 ERA over his last 5 starts.
  • He was rocked for 7 ER on 9 H and 1 BB with 5 K in 4 2/3 IP May 24 at Houston.

Astros at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:53 a.m. ET.

  • Money line (ML): Astros -200 (bet $200 to win $100) | Guardians +160 (bet $100 to win $160)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (-115) | Guardians +1.5 (-105)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Astros at Guardians picks and predictions

Prediction

Astros 5, Guardians 2

Money line

Houston’s offense has been a little shaky of late, but Verlander has been unbeatable. He’s pitching at a level similar to the Cy Young contender he was before Tommy John surgery. His K-rate is still a little low for his standards, but he is approaching 40 years old. He keeps rolling, and my favorite bet in the game is ASTROS FIRST 5 INNINGS (-130).

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Run line/Against the spread

As mentioned, Houston has just 4 wins in its last 10 games, but 3 of those came by more than 1 run. Plesac’s stuff is very hittable and Verlander has not been. I’ll take ASTROS -1.5 (-115) for a HALF UNIT.

Over/Under

It’s 83 degrees with a 4-mph wind coming in from right-center field, and there’s a 62% chance of rain. Cleveland has cashed 5 Overs in a row. Houston has cashed 4 Unders in a row. In fact, they’ve scored 6 runs or more just twice in the last 10 games. I’d be much happier if this number were 8.5, but LEAN UNDER 7.5 (+105) with Verlander on the warpath he’s on.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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