The Houston Astros (70-38) continue their road series against the Cleveland Guardians (54-52) with the 3rd game of their four-game series Saturday. First pitch is 6:10 p.m. ET at Progressive Field. Let’s analyze Tipico Sportsbook‘s lines around the Astros vs. Guardians odds with MLB picks and predictions.
Season series: Astros lead 4-1
The Astros have won 3 games in a row and 6 of their last 9. They took the first 2 games of the series 6-0 and 9-3. They can clinch a series victory with a win Saturday.
The Guardians entered this series having won 6 of 9 games but have lost twice by 6 runs. They trail the AL Central-leading Twins by 2 games.
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Astros at Guardians projected starters
RHP Luis Garcia vs. RHP Cal Quantrill
Garcia (8-7, 3.81 ERA) makes his 20th start. He has a 1.07 WHIP, 2.7 BB/9 and 9.5 K/9 through 106 1/3 IP.
- Garcia started the only loss the Astros have had this season against the Guardians. He allowed 4 runs (2 earned) in 5 innings of a 6-1 loss.
- His ERA is 2.72 in 9 road starts.
Quantrill (7-5, 4.08 ERA) makes his 21st start. He has a 1.32 WHIP, 2.6 BB/9 and 5.8 K/9 through 117 IP.
- The Guardians have won his last 5 starts.
- He has allowed 10 runs (9 earned) and 14 hits combined over his last 2 starts (11 1/3 IP).
Astros at Guardians odds and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:15 p.m. ET.
- Money line (ML): Astros -165 (bet $165 to win $100) | Guardians +133 (bet $100 to win $133)
- Run line (RL)/Against the spread (ATS): Astros -1.5 (+102) | Guardians +1.5 (-125)
- Over/Under (O/U): 8.5 (O: -115 | U: -107)
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Astros at Guardians picks and predictions
Prediction
Astros 6, Guardians 4
Money line
The Astros are 18-4 against the AL Central and 4-1 against Cleveland this season.
The Guardians are 28-29 against teams with winning records.
They have won Quantrill’s last 5 starts, but he was less effective in his last 2 outings.
Take the ASTROS (-165).
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Run line/Against the spread
The Astros are 56-52 ATS overall this season and 31-26 ATS on the road. Three of their 4 wins over the Guardians have been by more than 1 run. Nine of their last 10 wins overall have been by at least 2 runs.
The Guardians’ last 7 losses have been by more than 1 run. They are 24-25 ATS at home this season.
Take the ASTROS -1.5 (+102).
Over/Under
Three of the 5 games between these teams have had 8 or fewer runs.
Five of the last 6 games for the Astros have had fewer than 9 runs.
Meanwhile, 5 of the last 7 games for Cleveland have had 9 or more total runs.
Each of Quantrill’s last 8 starts has had totals of 9 or more runs.
Take OVER 8.5 (-115).
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