St. Louis Cardinals at San Francisco Giants odds, picks and predictions

Analyzing Monday’s St. Louis Cardinals at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (9-13) and San Francisco Giants (8-13) meet Monday to kick-off a 4-game series. First pitch from Oracle Park is set for 9:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting of 2023. St. Louis won the 2022 series 4-3.

St. Louis won 7-3 as a -106 road favorite Sunday vs. the Seattle Mariners to avoid being swept in the 3-game series. The Cardinals hit 3 home runs in the victory, including a 3-run shot from 2B Nolan Gorman in the 4th inning to give St. Louis a 6-3 lead. Monday marks the 4th game of a 10-game road trip for the Cards.

San Francisco won 5-4 as a +108 home underdog Sunday vs. the New York Mets. The Giants walked away with a 2-2 tie in that series after dropping the first 2 games and then winning back-to-back games Saturday and Sunday. This series will wrap up an 8-game homestand for San Francisco.

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Cardinals at Giants projected starters

LHP Jordan Montgomery vs. RHP Alex Cobb

Montgomery (2-2, 4.84 ERA) makes his 5th start. He has a 1.34 WHIP,  2.0 BB/9 and 7.7 K/9 through 22 1/3 IP.

  • Is making his first career appearance vs. San Francisco
  • Was 2-4 with a  3.75 ERA, 69 2/3 IP, 65 H, 29 ER, 17 BB and 59 K over 13 road starts for the Cardinals and New York Yankees in 2022

Cobb (0-1, 2.79 ERA) makes his 5th start. He has a 1.50 WHIP, 1.4 BB/9 and 10.2 K/9 through 19 1/3 IP.

  • Last start vs. St. Louis: 5 IP, 2 ER, 3 H, 1 BB and 8 K in a no-decision 3-2 loss on May 6, 2022
  • Was 6-6 with a 2.68 ERA, 87 1/3 IP, 75 H, 26 ER, 26 BB and 93 K across 16 home starts in 2022

Cardinals at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:55 a.m. ET.

  • Moneyline (ML): Cardinals -120 (bet $120 to win $100) | Giants +100 (bet $100 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+140) | Giants +1.5 (-165)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Cardinals at Giants picks and predictions

Prediction

Cardinals 6, Giants 4

Moneyline

BET CARDINALS (-120).

The Giants are 0-5 in their last 5 series openers and 1-8 in their last 9 games following a win. St. Louis has dropped its last 5 Monday games but holds a 7-3 lead in the last 10 matchups between these teams.

Run line/Against the spread

LEAN CARDINALS -1.5 (+140).

Both of these teams are 1-3 in 1-run games to start the season. Whichever team wins here will likely do so by more than 1 run, and the Cardinals have the advantage to win even as the road team.

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Over/Under

BET OVER 8 (-115).

The Over is 6-0 in St. Louis’ last 6 games when its opponent scored 5 or more runs in their previous game and 4-0-1 in its last 5 vs. a starting pitcher with a WHIP greater than 1.30.

The Over is 3-1-1 for San Francisco as a home underdog and 4-2-1 after a win this season.

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