St. Louis Cardinals at Cincinnati Reds odds, picks and predictions

Analyzing Wednesday’s St. Louis Cardinals at Cincinnati Reds odds and lines, with MLB expert picks and predictions.

The St. Louis Cardinals (75-55) and Cincinnati Reds (51-77) cap off a 3-game NL Central series Wednesday. First pitch from Great American Ball Park is slated for 6:40 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cardinals vs. Reds odds with MLB picks and predictions.

Season series: St. Louis leads 8-5

The Cardinals banged out 4 home runs among their 13 hits in Monday’s 13-5 win over the Reds. St. Louis then had just 4 hits in Tuesday’s 4-1 loss that snapped a 3-game win streak.

The Reds clocked a 5.43 ERA in 9 games prior to holding the Cards to 1 run Tuesday. Cincinnati is just 7-14 in its last 21 games.

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Cardinals at Reds projected starters

LHP Jose Quintana vs. LHP Mike Minor

Quintana (4-6, 3.45 ERA) has made 25 starts in 2022. He has a 1.32 WHIP, 3.0 BB/9 and 7.6 K/9 in 127 2/3 IP.

  • Owns a 2.17 ERA in his last 7 starts
  • Tossed 5 shutout innings against the Reds on May 15

Minor (3-10, 6.10 ERA) is tabbed for his 16th start. He has a 1.54 WHIP, 3.3 BB/9 and 7.5 K/9 in 79 2/3 IP.

  • Has struggled at home (6.37 ERA) and is up against a St. Louis club that leads the league in OPS against southpaws (.809)
  • Current Cardinals own a high-contact 1.049 OPS against him

Cardinals at Reds odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:20 p.m. ET.

  • Money line: Cardinals -240 (bet $100 to win $240) | Reds +190 (bet $190 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals -2.5 (+102) | Reds +2.5 (-125)
  • Over/Under (O/U): 9.5 (O: -107 | U: -115)

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Cardinals at Reds picks and predictions

Prediction

Cardinals 6, Reds 4

Money line

The betting signals here cross back and forth around a Cardinals -225 equilibrium. That spells no value on these prices: AVOID.

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Run line/Against the spread

Same calculus on the run-line side of things, at both 1.5 and 2.5 runs.

St. Louis owns a .371 batting average on balls in play with runners in scoring position over the last month. Figure on some fade lean away from the Redbirds in the near future, but this pitching matchup and Cincy’s offensive struggles lately make for too much uncertainty.

STEER CLEAR.

Over/Under

BACK THE OVER 9.5 (-105).

There is some slight lean against Quintana and in favor of a Redbirds offense that hits left-handers hard. Mix in a forecast for a batter’s breeze in a ballpark that is batter-friendly to begin with.

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