St. Louis Cardinals at Arizona Diamondbacks odds, picks and predictions

Analyzing Monday’s St. Louis Cardinals at Arizona Diamondbacks odds and lines, with MLB expert picks, predictions and best bets.

The Arizona Diamondbacks (54-46) welcome the St. Louis Cardinals (44-56) to Chase Field Monday. First pitch for the opener of this 3-game series is set for 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Diamondbacks odds and make our expert MLB picks and predictions for the best bets.

Season series: Diamondbacks lead 2-1

The Diamondbacks enter on a 4-game losing streak after getting swept in 3 at the Cincinnati Reds and are 2-8 over their last 10 (since the All-Star break). Arizona is 26-24 at home and 4 games behind the Los Angeles Dodgers for the top spot in the NL West.

The Cardinals are 6-4 since the break but have lost 3 in a row. They just dropped 3 of 4 at the Chicago Cubs, losing the series finale 7-2 Sunday. St. Louis is 22-30 on the road and 11 games back in the NL Central.

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Cardinals at Diamondbacks projected starters

RHP Adam Wainwright vs. TBD

Wainwright (3-4, 7.66 ERA) is expected to come off the injured list (shoulder irritation) to make his 12th start of the season. He has a 1.99 WHIP, 3.3 BB/9 and 4.9 K/9 through 51 2/3 innings.

  • Last start: Loss, 3 1/3 IP, 7 R (4 ER), 7 H, 2 BB, 3 K in 15-2 loss at Miami Marlins July 4
  • Last 3 starts: Allowed 4 or more ER in 3 straight games, 0-3, 19.13 ERA (8 IP, 17 ER)
  • Cardinals are 4-7 in his 11 starts, yet 3-2 in his 5 road starts
  • Career vs. D-backs: 11-6, 3.35 ERA (99 1/3 IP, 37 ER), including 0-1 in 1 start last year (6 IP, 3 ER, 4 H, 5 BB, 4 K in 6-2 home loss)

Arizona hasn’t officially named a starting pitcher, but all signs point to RHP Ryne Nelson (6-5, 4.82 ERA) being given the nod. He has a 1.38 WHIP, 2.5 BB/9 and 6.2 K/9 in 106 1/3 innings (20 starts).

  • Last start: Win, 7 IP, 2 ER, 3 H, 1 BB, 5 K in 5-3 victory at Atlanta Braves Wednesday
  • Been on fire lately, yielding 2 or fewer ER in 4 of last 5 starts
  • Home splits: 2-4, 8.08 ERA (42 1/3 IP, 38 ER) in 9 starts
  • Never faced Cardinals before

Cardinals at Diamondbacks odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:27 p.m. ET.

  • Moneyline (ML): Cardinals +115 (bet $100 to win $115) | Diamondbacks -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-165) | Diamondbacks -1.5 (+135)
  • Over/Under (O/U): 10 (O: -105 | U: -115)

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Cardinals at Diamondbacks picks and predictions

Prediction

Diamondbacks 6, Cardinals 3

Moneyline

BET DIAMONDBACKS (-140).

Arizona has been terrific this season as an ML favorite, going 30-18, according to Teamrankings.com.

It gets even better as a home favorite, in which the organization is 18-10 straight up. With Nelson likely on the mound and pitching well, the Diamondbacks are bound to bounce back after getting swept this past weekend.

St. Louis is 12-16 as a road underdog. The Cardinals are also just 24-31 following a loss, which is the case since they lost at Wrigley Field Sunday.

With the difference in pitchers and performances trends, TAKE DIAMONDBACKS (-140).

Run line/Against the spread

PASS.

There’s no real value here. The Diamondbacks haven’t been great at home and aren’t performing well, so backing them to win by more than a run isn’t quite worth the risk at just +135.

Similarly, Wainwright hasn’t pitched in 20 days and could struggle to contain Arizona. St. Louis getting 1.5 runs is not worth the juice at -165. Ultimately, play Arizona ML to win outright for the best team-specific wager.

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Over/Under

LEAN UNDER 10 (-115).

Arizona’s Under at home has been a consistently good bet this season as the D-backs feature a 19-27-4 O/U home record.

While St. Louis is 49-46-5 on the Over, it’s just 24-29-2 O/U following a loss. Wainwright is rested, which may aid his performance, and Nelson has been dealing lately.

BACK UNDER 10 (-115).

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