Southern Miss at South Alabama odds, picks and predictions

Analyzing Tuesday’s Southern Miss at South Alabama odds and lines, with college football expert picks, predictions and best bets.

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The Southern Miss Golden Eagles (1-5, 0-3 Sun Belt) and the South Alabama Jaguars (3-3, 1-1) meet Tuesday at Hancock Whitney Stadium in Mobile, Ala. Kickoff is scheduled for 7:30 p.m. ET (ESPN2). Below, we analyze BetMGM Sportsbook’s lines around the Southern Miss vs. South Alabama odds, and make our expert college football picks and predictions.

The Golden Eagles haven’t won since the Sept. 2 opener against Alcorn State of the FCS. Southern Miss has lost all 5 games against FBS teams, while also failing to cover in all of those outings.

The USM offense has shown some signs of life, however, scoring 36 or more points in 2 of the past 3 games. The defense has been putrid, though, giving up 44 or more points in 3 of the past 5 games, with the Over going 4-2 overall this season.

The Jaguars humbled Louisiana-Monroe last time out, winning 55-7 on the road to cover a 10.5-point number. That snapped a mini 2-game loss and non-cover skid. In 3 wins, including a road outing at Oklahoma State, USA has scored 33 or more points, while allowing 17 or fewer. In 3 losses, the Jags have coughed up 31 or more points, while scoring 30 or fewer.

At home, South Alabama is 1-1 SU and 0-2 ATS, losing its only game against an FBS team, Central Michigan, as a 16.5-point favorite back on Sept. 23.

Rankings: US LBM Coaches Poll powered by USA TODAY Sports

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Southern Miss at South Alabama odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:23 a.m. ET.

  • Moneyline (ML): Southern Miss +625 (bet $100 to win $625) | South Alabama -1000 (bet $1,000 to win $100)
  • Against the spread (ATS): Southern Miss +17.5 (-105) | South Alabama -17.5 (-115)
  • Over/Under (O/U): 51.5 (O: -110 | U: -110)

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Southern Miss at South Alabama picks and predictions

Prediction

South Alabama 38, Southern Miss 17

Moneyline

South Alabama (-1000) will cost you 10 times your potential return, or a $10 profit for every $100 risked. That’s a ridiculous amount of risk for a small amount of profit, and it’s not even worth including in a several-team parlay.

PASS.

Against the spread

SOUTH ALABAMA -17.5 (-110) is worth playing lightly laying the big point total.

Southern Miss +17.5 (-110) has yet to win or cover in 5 games against FBS foes. It was able to roll up 37 points in its most recent road game at Arkansas State, but both of those teams are bad. This team will struggle to get out of the teens against a good USA side.

Over/Under

OVER 51.5 (-110) is worth playing lightly, but go with a half-unit play at most.

The Over has cashed in 2 of the past 3 games for USM, with the defense allowing 111 total points in the 3-game span. The Golden Eagles are abysmal on defense, allowing 188.2 rushing yards per game, and 35.3 PPG.

The Jaguars are a decent rushing team, and they’ll lean upon the run game against a bad USM defense. But USA is balanced on offense, too, and it will do its fair share of passing, too. The Jaguars have cashed the Over in 3 straight, going for 36.0 PPG in the span, and it will do a lot of the heavy lifting to get this total across the finish line.

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