San Francisco Giants at New York Yankees odds, picks and predictions

Analyzing Sunday’s San Francisco Giants at New York Yankees odds and lines, with MLB expert picks, predictions and best bets.

The San Francisco Giants (1-1) and New York Yankees (1-1) meet Sunday afternoon to cap off a 3-game series at Yankee Stadium. First pitch is slated for 1:35 p.m. ET (ESPN+). Below, we analyze BetMGM Sportsbook’s lines around the Giants vs. Yankees odds, and make our expert MLB picks and predictions.

Season series: Tied 1-1.

San Francisco rebounded from an Opening Day 5-0 shutout by posting a 7-5 win in Saturday’s game despite striking out 13 times. The Giants have been whiffed 29 times in 2 games.

New York is looking to jump out to a fast start as it did a year ago en route to notching a plus-1.48 average run differential and a 99-63 record. The Yankees went 15-6 in April, outscoring opponents 100-61.

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Giants at Yankees projected starters

RHP Ross Stripling vs. RHP Jhony Brito

Stripling went 10-4 with a 3.01 ERA in a swingman role for the Toronto Blue Jays last season. He registered a 1.02 WHIP, 1.3 BB/9 and 7.4 K/9 in 134 1/3 IP across 32 games (24 starts).

  • Current Yankees batters own an aggregate .697 OPS against him.
  • Walk rate in 2022 was the best of his 7-year career (career 2.1 BB/9).

Brito is a 25-year-old hurler making his Major League debut. In 2022, he pitched a combined 112 2/3 IP at Double- and Triple-A (11-4, 2.96 ERA, 1.15 WHIP, 35 BB, 91 K).

  • Clocked a 2.08 ERA over 13 IP in Grapefruit League action.
  • Owns an average mid-90s fastball and a slightly above-average change-up.

Giants at Yankees odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:17 a.m. ET.

  • Moneyline: Giants +125 (bet $100 to win $125) | Yankees -150 (bet $150 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-160) | Yankees -1.5 (+135)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Giants at Yankees picks and predictions

Prediction

Yankees 5, Giants 4

Moneyline

Stripling has allowed 5 ER (and 3 HR) over 6 career IP spanning 2 appearances at Yankee Stadium. Last year, New York batters faced him twice and slashed a .324/.361/.471. Stripling usually has more trouble on hard-hit balls against right-handed bats despite being a righty, and that’s a major concern when facing this Yankee lineup.

Brito mixes in plenty of gray area here, but with the way New York usually plays at home and the home nine owning the deeper bullpen, a YANKEES (-150) play is worth a partial-unit outlay.

Run line/Against the spread

A first-time starter nixes any aggression when taking on this game as a betting proposition. PASS on getting the Yanks by with a multi-run cushion.

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Over/Under

Again, the Brito start adds more chance to the mix. STEER CLEAR of betting the total in this one.

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