San Francisco Giants at Cleveland Guardians odds, picks and predictions

Analyzing Sunday’s San Francisco Giants at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (44-46) and Cleveland Guardians (55-32) wrap up a 3-game interleague series Sunday. First pitch from Progressive Field is scheduled for 1:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

After winning Friday’s opener 4-2, the Giants lost 5-4 on Saturday as the Guardians (-123) cashed as home favorites with the Over (8.5) just coming in. San Francisco tries for the series win Sunday. The Giants have won 3 straight series, going 8-4 across the past 12 outings. The Over on Saturday halted a 3-0 run to the Under.

The Guardians have alternated wins and losses in the past 8 games dating back to June 28, going 4-4 in the previous 8 contests. The Over has hit in 4 of the past 5 outings, and 6 of the past 8 games.

In interleague play, San Francisco have won 6 of the past 11 games, while the Over is 4-2 in the past 6 outings against the AL.

For Cleveland, it is 7-5 in the past 12 interleague battles, while going 6-2 at home this season against NL foes. The Under is 4-3-1 in 8 home games vs. NL teams.

Giants at Guardians projected starters

RHP Hayden Birdsong vs. RHP Carlos Carrasco

Birdsong (1-0, 4.66 ERA) makes his 3rd career start. He has a 1.55 WHIP, 2.2 BB/9 and 8.2 K/9 in 9 2/3 IP.

  • Last start: Win, 5 IP, 2 ER, 4 H (2 solo HR), 2 BB, 5 K in 5-3 road victory vs. Atlanta Braves Tuesday in 1st career road start
  • Made 38 starts (8-7, 3.02 ERA) in 3 minor league seasons

Carrasco (3-6, 5.21 ERA) makes his 16th start. He has a 1.36 WHIP, 2.8 BB/9 and 7.2 K/9 in 76 IP.

  • Last start: No-decision, 6 IP, 3 ER, 4 H (2 HR), 1 BB, 7 K in 7-6 home win vs. Chicago White Sox Tuesday
  • 2024 home splits: 2-3, 4.55 ERA (31 2/3 IP, 16 ER), 1.42 WHIP, .294 OBA, 10 BB, 28 K in 6 starts
  • Career vs. Giants: 1-2, 2.95 ERA (39 2/3 IP, 13 ER), 0.88 WHIP, 7.7 K/9 in 6 starts (1 CG)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Giants at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:09 a.m. ET.

  • Moneyline (ML): Giants +110 (bet $100 to win $110) | Guardians -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-175) | Guardians -1.5 (+145)
  • Over/Under (O/U): 9 (O: -110 | U: -110)

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Giants at Guardians picks and predictions

Prediction

Guardians 5, Giants 4

Moneyline

The GUARDIANS (-135) are worth a look in Sunday’s finale against the Giants (+110), but be careful and go lightly.

Carrasco has been slightly better at home, although he is still fairly giving. He has served up 6 HR with a .294 OBA in 31 2/3 IP across 6 starts.

However, Birdsong is making just his 3rd career start, and 2nd on the road. He is facing the best team in the AL, at least in terms of win percentage, and that’s a tough assignment for the 22-year-old rookie.

Run line/Against the spread

If you’re a little more on the conservative side, GIANTS +1.5 (-175) isn’t priced out of line if you want a little bit of insurance.

The Guardians -1.5 (+145) haven’t won consecutive games since June 24-25 in Baltimore, and 2 of the team’s past 3 victories have been by a single run.

Over/Under

PASS on the total 9, as it should come right down on the number.

If there was a lean, it would be to go high, as Carrasco has been hit for plenty of crooked numbers this season. And the Over is 6-2 in the past 8 games for Cleveland.

The Giants have hit the Under at a 3-1 pace in the past 4 games, but the Over is still 14-7-1 across the previous 22 contests.

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