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The Cleveland Guardians (54-31) welcome the San Francisco Giants (43-45) to Progressive Field Friday for the opener of their 3-game series. First pitch is set for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Giants vs. Guardians odds and make our expert MLB picks and predictions for the best bets.
Season series: First meeting; Giants took 2 of 3 games in 2023
The Giants beat the Atlanta Braves 4-2 Thursday, closing at +111 on the moneyline. They won 2 of 3 in the series and have won 4 of their last 6 games. San Francisco has been awful on the road this season at just 18-26, the 7th-worst road record in the majors. It is 42-46 against the spread (ATS).
The Guardians beat the Chicago White Sox 8-4 at home Thursday, closing as a sizable -214 favorite. They have traded off winning and losing over their last 6 games and are 3-5 straight up over their last 8 games. Cleveland is 7-1 in its last 8 at home and 28-10 at home on the season. It is 48-37 ATS.
Giants at Guardians projected starters
Undecided vs. RHP Tanner Bibee
Giants pitcher has yet to be named with no inclination as to who will start.
Bibee (7-2, 3.47 ERA) makes his 18th start. He has a 1.09 WHIP, 2.1 BB/9 and 10.5 K/9 in 93 1/3 IP.
- Last start: Win, 6 IP, 2 R, 4 H, 0 BB, 3 K in 7-2 road win over the Kansas City Royals Saturday
- 2024 home splits: 3-1, 4.36 ERA (43 1/3 IP, 21 ER), 1.15 WHIP, 5 HR, 11.0 K/9 in 8 starts
- Has never faced Giants
Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.
Giants at Guardians odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:13 a.m. ET.
- Moneyline (ML): Giants +144 (bet $100 to win $144) | Guardians -172 (bet $172 to win $100)
- Run line (RL)/Against the spread (ATS): Giants +1.5 (-156) | Guardians -1.5 (+130)
- Over/Under (O/U): 8.5 (O: -110 | U: -110)
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Giants at Guardians picks and predictions
Prediction
Guardians 6, Giants 3
Moneyline
PASS.
The Guardians have been so good at home that they are a strong favorite here, but they are also unplayable as a straight-up moneyline favorite. They are too expensive while the Giants are too risky.
Avoid this play.
Run line/Against the spread
BET GUARDIANS -1.5 (+130).
The Guardians have been almost unbeatable when Bibee takes the mound. They are 14-3 in his starts and have won 8 of those games by more than 1 run. Cleveland is 5-3 ATS in its last 5 home games. It is 21-17 ATS at home, the 3rd-best home ATS record in the majors.
Meanwhile, the Giants are 22-21 ATS on the road. While above .500, that still sits in the bottom 3rd of the league. San Fran is 2-3 ATS in its last 5 on the road. Considering Bibee’s strength and the Giants’ struggles in away games, back GUARDIANS -1.5 (+130).
Over/Under
BET OVER 8.5 (-110).
The Giants are 4-2-1 O/U in their last 7 games and 48-37-3 O/U on the season. They have scored at least 5 runs in 4 of their last 6 games.
The Guardians, who are 2-1 O/U in Bibee’s last 3 starts, have gone north of the total in 3 straight games and in 5 of their last 6. They have scored at least 7 runs in 3 of their last 5 games while allowing at least 6 runs in 3 of their last 4.
Considering those trends, back OVER 8.5 (-110).
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