San Francisco Giants at Chicago Cubs odds, picks and predictions

Analyzing Monday’s San Francisco Giants at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (70-67) and Chicago Cubs (73-64) open up a 3-game set at Wrigley Field Monday. First pitch is at 2:20 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Cubs lead 2-1

The Giants enter this one on a 3-game skid after losing 3 of 4 at the San Diego Padres from Thursday to Sunday. San Francisco is just 8-12 and 12-18 over the last 20 and 30 games, respectively, and is in a 4-way tie for the final NL Wild Card spot.

The Cubs are securely in the 2nd NL Wild Card spot, 3 games up on those 4 teams tied for the final spot. They have gone 6-4, 12-8 and 19-11 over the last 10, 20 and 30 games, respectively. It has been a banner year for the Cubbies thus far, and they have arguably their best starter going Monday.

Giants at Cubs projected starters

RHP Logan Webb vs. LHP Justin Steele

Webb (9-11, 3.49 ERA) makes his 29th start. He has a 1.10 WHIP, 1.3 BB/9 and 8.4 K/9 in 180 1/3 innings.

  • Last start: Loss, 6 IP, 2 ER, 7 H, 0 BB, 6 K Wednesday against Cincinnati Reds
  • 2 career starts vs. Cubs: 2-0, 4.85 ERA, 1.15 WHIP, 11 K in 13 IP

Steele (15-3, 2.69 ERA) makes his 26th start. He has a 1.17 WHIP, 1.9 BB/9 and 8.8 K/9 in 144 innings.

  • Last start: Win, 6 IP, 0 ER, 6 H, 1 BB, 8 K Tuesday against the Milwaukee Brewers
  • 2 career starts vs. Giants: 0-2, 4.15 ERA, 2.08 WHIP, 10 K in 8 2/3 IP

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Giants at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:34 a.m. ET.

  • Moneyline (ML): Giants +115 (bet $100 to win $115) | Cubs -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-165) | Cubs -1.5 (+135)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Giants at Cubs picks and predictions

Prediction

Cubs 6, Giants 4

Moneyline

Steele hasn’t lost in his last 8 starts and is 11-2 with a 2.46 ERA at home this season. There is a lot to like on the Cubs’ side. The Giants have scored 3 runs or fewer in 6 of 10 games. After scoring 7 against the Padres Thursday, they plated just 4 runs the next 3 games.

Steele and the CUBS (-140) roll.

Run line/Against the spread

The Cubs are just 34-34 on the RL at home, and it’s too volatile to lean either way in this one.

PASS.

Over/Under

The wind will be a factor as it is blowing out to left-center at 11 mph. There are a lot of Under trends to use caution with, though. The Giants are 4-6 O/U over the last 10, and Chicago is 3-7 O/U during the same stretch. The Over is just 2-8 in the last 10 meetings. The wind blowing out at Wrigley changes things, though.

LEAN OVER 9 (-105).

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