San Francisco Giants at Arizona Diamondbacks odds, picks and predictions

Analyzing Wednesday’s San Francisco Giants at Arizona Diamondbacks odds and lines, with MLB expert picks, predictions and best bets.

[gambcom-standard rankid=”3011″ ]

The San Francisco Giants (76-75) wrap up a 2-game road series against the Arizona Diamondbacks (80-72) Wednesday. First pitch from Chase Field is at 3:40 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Diamondbacks odds and make our expert MLB picks and predictions for the best bets.

Season series: tied 6-6

The Giants lost the opener 8-4 Tuesday despite scoring 2 runs in the top of the 1st inning. They have lost 4 of their last 5 games and are 6-11 in their last 17, falling 3 games behind the final NL Wild Card spot.

The Diamondbacks have won 4 in a row. They are currently the No. 2 NL Wild Card, half a game up on the Chicago Cubs and 3 games behind the Philadelphia Phillies for the top NL Wild Card.

Giants at Diamondbacks projected starters

RHP Logan Webb vs. RHP Merrill Kelly

Webb (10-12, 3.31 ERA) makes his 32nd start. He has a 1.06 WHIP, 1.3 BB/9 and 8.2 K/9 through 201 IP.

  • Last start: No-decision, 8 IP, 1 ER, 4 H, 0 BB, 6 K in 3-2 road loss vs. Colorado Rockies Friday
  • 2-0 with 2.57 ERA in 3 starts vs. Arizona this season

Kelly (11-7, 3.45 ERA) makes his 28th start. He has a 1.21 WHIP, 3.5 BB/9 and 9.7 K/9 through 159 IP.

  • Last start: Loss, 5 IP, 7 ER, 6 H, 4 BB, 7 K in 11-1 road loss vs. New York Mets Thursday
  • 6-5 with 3.48 ERA and 1.20 WHIP in 17 career starts vs. Giants

Play our free daily Pick’em Challenge and win! Play now!

Giants at Diamondbacks odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:27 a.m. ET.

  • Moneyline (ML): Giants -115 (bet $115 to win $100) | Diamondbacks -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants -1.5 (+150) | Diamondbacks +1.5 (-185)
  • Over/Under (O/U): 7.5 (O: -120 | U: +100)

[gambcom-standard rankid=”3012″ ]

Giants at Diamondbacks picks and predictions

Prediction

Diamondbacks 4, Giants 2

Moneyline

Kelly has 2 bad starts (7 ER allowed in each) in his last 11 turns, but he allowed 2 ER or fewer 7 times along that span. The Diamondbacks are 4-2 in his last 6 outings.

The Giants have lost 5 of Webb’s last 6 starts and have lost 10 of their last 11 road games overall.

BET DIAMONDBACKS (-105).

Run line/Against the spread

The Giants have not covered the spread in their last 8 games and are 2-15 ATS in their last 17.

The Diamondbacks are 4-0 ATS in their last 4 games. Three of their last 4 wins have been by 2 or more runs and 4 of their 6 wins over the Giants have been by 2 or more runs, so while betting them at +1.5 isn’t profitable, you might consider a small wager on an alternate line of DIAMONDBACKS -1.5 (+185).

Over/Under

Four of Webb’s last 5 and 7 of his last 9 starts have not reached 8 total runs.

Half of the 12 games between the 2 teams have stayed under 8 total runs.

BET UNDER 7.5 (+100).

[gambcom-standard rankid=”5″ ]

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Jess Root on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Additional MLB coverage:
BaseballHQ Fantasy Baseball

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1372]