San Francisco Giants at Arizona Diamondbacks odds, picks and predictions

Analyzing Monday’s San Francisco Giants at Arizona Diamondbacks odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (87-69) welcome the San Francisco Giants (77-79) to Chase Field Monday for the 1st game of a 3-game series. First pitch is set for 9:40 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s MLB odds around the Giants at Diamondbacks odds and make our expert MLB picks and predictions for the best bets.

Season series: Diamondbacks lead 6-4

The Giants beat the Kansas City Royals 2-0 Sunday to complete the 3-game sweep, outscoring the Royals 13-1. The Giants have won 5 of their last 6 games, all on the road. They are 36-42 in away games this season and 76-80 against the spread (ATS).

The Diamondbacks lost 10-9 to the Milwaukee Brewers in a shootout Sunday. Arizona has scored at least 5 runs in 5 straight games and has won 4 of those. It is 43-33 at home, yet is just 5-7 over its last 12 games at home. The Diamondbacks are 81-74 ATS.

Giants at Diamondbacks projected starters

RHP Hayden Birdsong vs. LHP Eduardo Rodriguez

Birdsong (4-5, 4.74 ERA) makes his 15th career start. He has a 1.39 WHIP, 5.5 BB/9 and 10.2 K/9 in 62 2/3 IP.

  • Last start: Win, 5 2/3 IP, 3 ER, 4 H, 2 BB, 3 K in 5-3 road win over the Baltimore Orioles Wednesday
  • 2024 away stats: 3-3, 5.55 ERA (35 2/3 IP, 22 ER), 1.40 WHIP, 10.6 K/9 in 8 starts
  • Career vs. Diamondbacks: 0-1, 6.00 ERA (3 IP, 2 ER), 2.67 WHIP, 12.0 K/9 in 1 start

Rodriguez (3-3, 5.09 ERA) makes his 9th start. He has a 1.45 WHIP, 3.1 BB/9 and 8.0 K/9 in 40 2/3 IP.

  • Last start: Win, 6 1/3 IP, 2 ER, 5 H, 1 BB, 11 K in 9-4 road win over the Colorado Rockies Wednesday
  • 2024 home stats: 0-2, 6.05 ERA (19 1/3 IP, 13 ER), 1.55 WHIP, 8.4 K/9 in 4 starts
  • Career vs. Giants: 1-0, 1.50 ERA (6 IP, 1 ER), 0.83 WHIP, 15.0 K/9 in 1 start

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Giants at Diamondbacks odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated Sunday at 10:47 p.m. ET.

  • Moneyline (ML): Giants +145 (bet $100 to win $145) | Diamondbacks -175 (bet $175 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-145) | Diamondbacks -1.5 (+120)
  • Over/Under (O/U): 9 (O: -115 | U: -105)

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Giants at Diamondbacks picks and predictions

Prediction

Diamondbacks 6, Giants 5

Moneyline

PASS.

The Diamondbacks are far too expensive of a favorite to play at home, especially considering how well the Giants have played as of late. Similarly, the Giants aren’t worth a play on the moneyline and have more attractive odds on the spread.

Run line/Against the spread

BET GIANTS +1.5 (-145).

The Giants have been playing extremely well on the road and against competent opponents. Both the Royals and Orioles have winning  records and the Giants won 5 of 6 against those teams in their last 2 road series. San Francisco has allowed just 9 total runs in those 6 games and has allowed just 6 total runs in Birdsong’s last 2 starts.

Also, 2 of the last 3 games between these teams have ended within 1 run. The Diamondbacks have allowed 4 or more runs in 5 of their last 8 games and have outright lost in 3 of Rodriguez’s last 4 starts. Put it all together and back GIANTS +1.5 (-145).

Over/Under

BET OVER 9 (-110).

In the 10 games between these 2 teams this season, 6 of them would’ve gone Over this total. One team has scored at least 6 runs in 4 of the last 5 games and 1 team has scored at least 8 runs in 3 of those 5 games.

Neither starting pitcher has been consistently efficient this season. The Diamondbacks are 3-2 O/U in their last 5 games and 88-61-6 O/U on the season. The Giants have gone Over in 4 of their last 6 and are 79-71-6 O/U.

Back OVER 9 (-110).

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