The San Francisco 49ers (11-4) will go up against the Las Vegas Raiders (6-9) on Sunday in Week 17 at Allegiant Stadium. Kickoff is scheduled for 4:05 p.m. ET (FOX). Below, we analyze Tipico Sportsbook’s lines around the 49ers vs. Raiders odds, and make our expert NFL picks and predictions.
The 49ers cruised to a 37-20 win over the Washington Commanders in Week 16 to cover as 6.5-point favorites at home. San Francisco has reeled off 8 straight wins and is currently the No. 3 seed in the NFC.
The Raiders lost 13-10 to the Pittsburgh Steelers in Week 16 as they failed to cover as 2.5-point underdogs on the road. Las Vegas was eliminated from playoff contention in Week 16 and have elected to bench QB Derek Carr in favor of QB Jarrett Stidham in the final 2 weeks.
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49ers at Raiders odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 7:38 p.m. ET.
- Moneyline (ML): 49ers -450 (bet $450 to win $100) | Raiders +360 (bet $100 to win $360)
- Against the spread (ATS): 49ers -9.5 (-109) | Raiders +9.5 (-111)
- Over/Under (O/U): 42.5 (O: -110 | U: -110)
49ers at Raiders key injuries
49ers
- DE Nick Bosa (illness) questionable
- WR Deebo Samuel (ankle/knee) questionable
- DT Arik Armstead (foot/ankle) questionable
- RB Christian McCaffrey (knee) questionable
Raiders
- QB Derek Carr (coach’s decision) out
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49ers at Raiders picks and predictions
Prediction
49ers 34, Raiders 13
Moneyline
Go ahead and AVOID the moneyline in this game despite San Francisco being close to double-digit favorites. While the 49ers should easily win, taking them straight up isn’t advised at the current odds.
Against the spread
49ers -9.5 (-109) is an easy choice in this game despite 9.5-point spreads being tough to cover in the NFL. Stidham will be making his 1st career start on Sunday against San Francisco’s No. 1 ranked defense.
The 49ers are 5-0 ATS in their last 5 games following an ATS win and 6-0 ATS in their last 6 games following a win.
Over/Under
Even though the Raiders could have a tough time scoring points, OVER 42 (-110) is an intriguing wager. The 49ers have been rolling with QB Brock Purdy under center and the defense should give him more possessions on Sunday, resulting in plenty of points for San Francisco.
The 49ers have hit the Over in 3 of their last 4 games overall. Meanwhile, the Raiders are 4-1 to the Over in 4 of their last 5 games against a team with a winning record.
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