San Francisco 49ers at Dallas Cowboys odds, picks and prediction

Previewing the San Francisco 49ers at Dallas Cowboys Week 15 betting odds and lines, with NFL betting picks, tips and predictions.

The San Francisco 49ers (5-8) visit “Jerry’s World” Sunday for a Week 15 game against the Dallas Cowboys (4-9) at the AT&T Stadium. Kickoff is scheduled for 1 p.m. ET. Below, we preview the 49ers-Cowboys betting odds and lines and make our NFL picks and predictions.

49ers at Cowboys: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 10:48 p.m. ET.

  • Money line: 49ers -175 (bet $175 to win $100) | Cowboys +145 (bet $100 to win $145)
  • Against the spread/ATS: 49ers -3 (-110) | Cowboys +3 (-110)
  • Over/Under: 44.5 (O: -115 | U: -105)

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49ers at Cowboys: Game notes

  • Playing at its temporary home in Glendale, Ariz., San Francisco was dominated by the Washington Football Team’s defense in a 23-15 loss in Week 14. The 49ers’ defense kept Washington’s offense out of the end zone, but WFT scored two defensive touchdowns, including DE Chase Young’s 47-yard fumble return and S Kamren Curl’s 76-yard interception return.
  • 49ers’ gambling records: 5-8 ATS and 6-7 O/U.
  • Dallas eased past the host Cincinnati Bengals 30-7 in QB Andy Dalton’s revenge game last week. However, the result was based more on the Bengals losing than the Cowboys winning. Dallas had fewer first downs and total yards than Cincinnati, and only possessed the ball for 25:19. The Cowboys defense forced 3 turnovers, including DE Aldon Smith’s 78-yard fumble return for a score.
  • Cowboys’ gambling records: 3-10 ATS and 7-6 O/U.
  • While these storied franchises have been NFC rivals for decades, they haven’t played a meaningful head-to-head game in years. The last meeting ended in a Cowboys’ 40-10 road win in 2017.

49ers at Cowboys: Key injuries

49ers

  • WR Deebo Samuel (hamstring) out
  • Hroniss Grasu (knee) out
  • LB Fred Warner (stinger) questionable
  • CB K’Waun Williams (ankle) questionable
  • CB Emmanuel Moseley (hamstring) questionable

Cowboys

  • RB Ezekiel Elliott (calf) questionable
  • FS Xavier Jones (groin) questionable
  • CB Deante Burton (shoulder) out
  • CB Rashard Robinson (knee) questionable

49ers at Cowboys: Odds, betting lines, predictions and picks

Prediction

Cowboys 24, 49ers 20

Money line (?)

A lot has happened since the 49ers lost in Super Bowl 54, and based on their 2020 returns, they shouldn’t be a road favorite over a team that has one less loss. When you audit the 49ers’ wins there isn’t a lot to be impressed with.

San Francisco beat NFC West rival Los Angeles Rams twice, which head coach Kyle Shanahan seemingly has cast a spell on, an extremely one-dimensional New England Patriots squad, a winless New York Jets team and a 5-8 New York Giants team.

This is more of a bet against an overrated 49ers team, but I’ll TAKE COWBOYS (+145) for a half-unit.

Against the spread (?)

The market apparently doesn’t agree with the old football adage that you are what your record says you are. According to Pregame.com, 60% of the money bet is on the 49ers, which has pushed them from a 2.5-point favorite when the line opened to the current -3.

The public betting a road favorite is a nice spot if you believe in the fade the market handicapping angle. There is too much talent on this Cowboys team for it to be 3-10 ATS this season. That record is going to even out a little. Playing a 49ers team which has lost five of its last six ATS is a good matchup for Dallas.

GIMME COWBOYS +3 (-110) for 1 unit.

Over/Under (?)

PASS ON THE TOTAL with a slight lean on the Over 44.5 (-115). Even 49ers backup QB Nick Mullens can put up points against a Cowboys defense which ranks dead last in points allowed per game. Plus, all the injuries to San Francisco’s defense make that unit a shell of its 2020 self.

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