San Diego Padres at St. Louis Cardinals odds, picks and predictions

Analyzing Monday’s San Diego Padres at St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (74-58) and St. Louis Cardinals (65-65) open up a 4-game series Monday at Busch Stadium at 7:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 2-1

The Padres took 2 of 3 over the weekend against the New York Mets. They took Sunday’s game 3-2 as they entered the 8th inning down 2-0. OF Jackson Merrill hit a walk-off homer against RHP Edwin Diaz to send the home crowd in a frenzy. Merrill is hitting .304 with 7 homers and 22 RBIs over the last 30 days. He has now become the favorite to win NL Rookie of the Year (-165 at BetMGM Sportsbook).

The Cards stole one Sunday as an error allowed runners on 2nd and 3rd with 1 out in the top of the 9th. On cue, the next batter struck out before OF Lars Nootbaar drove in both runs with a base hit. They’ve won 4 of 5, against playoff teams no less, yet still remain 5 games out of a Wild Card spot.

Padres at Cardinals projected starters

RHP Randy Vasquez vs. RHP Kyle Gibson

Vasquez (3-6, 4.63 ERA) makes his 18th start. He has a 1.51 WHIP, 2.4 BB/9 and 5.8 K/9 in 81 2/3 IP.

  • Last start: No-decision, 5 2/3 IP, 3 ER, 6 H, 1 BB, 3 K in 7-6 victory Aug. 8 at Pittsburgh Pirates
  • Hasn’t faced Cardinals
  • Home/road splits: 2-3, 6.08 ERA, 1.70 WHIP, 5.4 K/9 in 9 road starts; 1-3, 3.24 ERA, 1.32 WHIP, 6.3 K/9 in 8 home starts

Gibson (7-5, 4.22 ERA) makes his 25th start. He has a 1.36 WHIP, 3.4 BB/9 and 8.3 K/9 in 136 1/3 IP.

  • Last start: No-decision, 5 1/3 IP, 2 ER, 7 H, 2 BB, 5 K in 10-6 home victory in 10 innings Wednesday against Milwaukee Brewers
  • Last 5 starts against Padres: 2-1, 4.76 ERA, 1.31 WHIP, 19 K in 28 1/3 IP

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Padres at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:50 p.m. ET.

  • Moneyline (ML): Padres +100 (bet $100 to win $100) | Cardinals -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+155) | Cardinals +1.5 (-190)
  • Over/Under (O/U): 9 (O: -120 | U: +100)

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Padres at Cardinals picks and predictions

Prediction

Cardinals 5, Padres 4

Moneyline

Gibson beat the Padres early in the season, allowing 2 ER on 4 H and 2 BB while fanning 4 in 7 IP. His biggest task will be to keep the Padres in the ballpark. He has allowed 1 homer in his last 5 home starts, spanning 24 1/3 IP.

Vasquez doesn’t have the kind of stuff that should elude Cardinals bats. His 4-seamer averages 94 mph, and opposing hitters are hitting .338 off of it. The CARDINALS -120 sneak one out.

Run line/Against the spread

The Padres are the hardest team to strike out in baseball, but I LOVE KYLE GIBSON OVER 3.5 K’S (-140). He has 5+ K’s in 4 straight starts and fanned 4 Padres in his previous start.

Over/Under

It is HOT in St. Louis. It’s expected to be 97 degrees at first pitch with a 7-mph win blowing out toward left-center. Having said that, I don’t trust this Cardinals offense enough to go for an Over at -120, though the pitching matchup leans that way.

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