San Diego Padres at New York Yankees odds, picks and predictions

Analyzing Saturday’s San Diego Padres at New York Yankees odds and lines, with MLB expert picks, predictions and best bets.

The San Diego Padres (24-27) will play the 2nd game of a 3-game series against the New York Yankees (30-23) on Saturday at Yankee Stadium. First pitch is scheduled for 1:05 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Yankees odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 1-0

The Padres secured a 5-1 victory over the Yankees Friday in the series opener. San Diego has won 4 of its last 5 games and is 6.5 games behind the Los Angeles Dodgers for 1st place in the NL West.

Yankees RHP Randy Vasquez allowed 2 ER on 4 H with 3 BB and 6 K in 4 2/3 IP in his major league debut Friday. New York is amid a 3-game losing skid following a 5-game winning streak from May 18-23.

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Padres at Yankees projected starters

RHP Michael Wacha vs. RHP Luis Severino

Wacha (5-1, 3.58 ERA) makes his 10th start. He has a 1.15 WHIP, 2.5 BB/9 and 8.0 K/9 through 50 1/3 IP.

  • Has given up only 1 ER across 25 IP over his last 4 turns but allowing 19 ER over 25 1/3 IP through his first 5 starts
  • Has recorded a quality start in 5 of his first 9 starts

Severino (0-0, 1.93 ERA) makes his 2nd start. He has a 1.07 WHIP, 1.9 BB/9 and 9.6 K/9 through 4 2/3 IP.

  • Allowed 1 ER on 4 H with 1 BB and 5 K in 4 2/3 IP in his season debut vs. the Cincinnati Reds Sunday
  • Could be in line for an increased pitch count after tossing just 75 in his debut

Padres at Yankees odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:17 a.m. ET.

  • Moneyline (ML): Padres +120 (bet $100 to win $120) | Yankees -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres +1.5 (-165) | Yankees -1.5 (+140)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Padres at Yankees picks and predictions

Prediction

Yankees 5, Padres 4

Moneyline

I’ll back the YANKEES (-145) at home in Saturday’s interleague matchup despite that they’ve lost 3 games in a row. New York is 17-13 at home compared to San Diego’s 12-12 record on the road this season.

Run line/Against the spread

PASS.

Unless you can get the Padres’ run line at -160 odds or better, then I’d advise avoiding the spread in this game and just focusing on the moneyline and/or total.

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Over/Under

OVER 8.5 (-110) is an intriguing wager despite how Wacha has been pitching recently for the Padres. Wacha owns an 8.2% barrel percentage and the Yankees boast a .199 ISO (5th best in baseball) at home against right-handed pitching.

The Padres have also shown some life with their bats in recent games and Severino is only making his 2nd start of the season.

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