San Diego Padres at Minnesota Twins odds, picks and predictions

AnalyzingTuesday’s San Diego Padres at Minnesota Twins odds and lines, with MLB expert picks, predictions and best bets.

The San Diego Padres (18-17) and Minnesota Twins (19-16) meet Tuesday as they swing into a 3-game series in Minneapolis. The first pitch from Target Field is slated for 7:40 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Padres vs. Twins odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; San Diego took 2 of 3 from Minnesota last season

The Padres are on the road after a 5-3 homestand. They struggled mightily on offense on their last road trip, a 4-3 voyage that saw the club slash a mere .193/.282/.323 (.605 OPS).

The Twins are back at home after a 2-4 road trip, and perhaps they wish they had logged a .605 OPS. Minnesota scored just 3.00 runs per game on a whiff-heavy .523 OPS. The Twins averaged 5.20 RPG over their last homestand April 21-30.

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Padres at Twins projected starters

RHP Michael Wacha vs. RHP Louie Varland

Wacha (2-1, 5.46 ERA) is making his 7th start. He’s logged a 1.40 WHIP, 2.6 BB/9 and 7.5 K/9 in 31 1/3 IP.

  • Last start May 2 vs. Cincinnati Reds: No-decision, 6 IP, 2 H, 0 ER, 2 BB, 3 K in 2-1 loss
  • Has held current Twins batters to an aggregate .677 OPS

Varland (0-0, 5.91 ERA) makes his 3rd start. He has a 1.50 WHIP, 2.5 BB/9 and 11.8 K/9 in 10 2/3 IP.

  • Has missed a lot of bats (15.3% swinging strikes) while displaying an uptick in velo
  • Has allowed barreled contact — including 4 HR — on 13.3% of balls in play
  • Has been hampered by a .346 batting average on balls in play

Padres at Twins odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:06 a.m. ET.

  • Moneyline: Padres -104 (bet $104 to win $100) | Twins -112 (bet $100 to win $112)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+150) | Twins +1.5 (-182)
  • Over/Under (O/U): 9 (O: -110 | U: -110)

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Padres at Twins picks and predictions

Prediction

Twins 6, Padres 5

Moneyline

Which Wacha will the Friars get this season? He of the 3.32 ERA a year ago? Or the veteran logging a 5.11 ERA from 2019-21? So far he looks more like the latter.

Varland has some upside, and Minnesota has hit well in its home park. But PASS, and look to leverage some partial-unit funds on the Twins if the price hits -110 or better.

Run line/Against the spread

PASS. The upside of this total is the likable angle on scoring, so the Run Line cushion does not offer as much as it would in, say, a 7-run environment.

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Over/Under

Both teams sports some early-season analytics indicating some negative regression due in pitching/defense. On a warmed-up evening in Minneapolis, with a Padres club that had been hitting of late before running into LA Dodgers pitching last weekend, and a hitting-well-at-home Minnesota squad, BACK THE OVER 9 (-110).

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