San Diego Padres at Los Angeles Angels odds, picks and predictions

Analyzing Tuesday’s San Diego Padres at Los Angeles Angels odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (32-31) and Los Angeles Angels (22-38) hook up for the 2nd game of a 3-game series Tuesday. First pitch from Angel Stadium is scheduled for 9:38 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Angels odds and make our expert MLB picks and predictions for the best bets.

Season series: Angels lead 1-0

The Padres have lost back-to-back games after falling 2-1 to the Angels Monday and failing to cover as -147 road favorites with the Under (8) easily hitting.

San Diego’s offense struggled as the only run came on 3B Manny Machado’s 1st-inning solo homer. LHP Adrian Morejon took the loss in relief, allowing 1 run in the bottom of the 8th. He was actually out of the game when the run scored, getting removed after RF Jo Adell’s leadoff double and a flyout, which moved Adell to 3rd. RHP Jeremiah Estrada entered and allowed a sacrifice fly to PH/2B Luis Guillorme as the Angels grabbed the 2-1 lead, which held up after a 1-2-3 top of the 9th.

The win snapped an Angels 5-game losing streak as they covered as +135 home underdogs despite being outhit 6-4. DH Willie Calhoun had the other Angels RBI — tying it at 1-1 with a 4th-inning single — while RHP Hunter Strickland (1 1/3 IP, 0 ER) picked up the win in relief.

Padres at Angels projected starters

RHP Adam Mazur vs. LHP Patrick Sandoval

Mazur will make his MLB debut after getting called up from Triple-A El Paso.

  • El Paso 2024 stats: 1-2, 7.11 ERA (19 IP, 15 ER), 1.32 WHIP, 1.9 BB/9, 8.5 K/9 in 4 starts since call-up from Double-A San Antonio
  • San Antonio 2024 stats: 3-1, 1.95 ERA (32 1/3 IP, 7 ER), 0.87 WHIP, 1.4 BB/9, 8.9 K/9 in 6 starts
  • Combined 2024 minor-league stats: 4-3, 3.86 ERA (51 1/3 IP, 22 ER), 1.03 WHIP. 1.6 BB/9, 8.8 K/9 in 10 starts

Sandoval (2-8, 5.34 ERA) makes his 13th start. He has a 1.48 WHIP, 1.0 BB/9 and 4.0 K/9 through 60 2/3 innings.

  • Last start: Loss, 6 IP, 2 ER, 2 H, 3 BB, 7 K in 8-3 home setback to New York Yankees Thursday
  • Angels are 3-9 in his 12 starts with Sandoval allowing 4 or more ER in 2 of his last 4 starts
  • Career vs. Padres: 1-0, 1.13 ERA (8 IP, 1 ER), 1.00 WHIP, 10 K in 2 games (1 start)

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Padres at Angels odds

Provided by BetMGM Sportsbook, one of the most popular betting apps; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:50 p.m. ET.

  • Moneyline (ML): Padres +100 (bet $100 to win $100) | Angels -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres +1.5 (+210) | Angels -1.5 (-160)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Padres at Angels picks and predictions

Prediction

Padres 4, Angels 3

Moneyline

BET PADRES (+100).

San Diego has won 2 of its last 4 on the road and 5 of its last 8 overall. It has held opponents to 4 or fewer runs in 7 of its last 9 games. It goes up against an Angels team that has lost 8 of its last 9, including 5 of its last 6. L.A. has allowed 5 or more runs in 4 of its last 5 games.

Run line/Against the spread

PASS.

With an unproven pitcher starting for San Diego (+1.5, -210), there is minimal value on the run line in this game. Plus, that’s too much juice.

Over/Under

BET UNDER 8.5 (-115).

The Padres have hit the Under in 6 of their last 10 games including back-to-back games. They have scored 4 or fewer runs in 7 of their last 10, while allowing 4 or fewer runs in 7 of their last 9.

The Angels have hit the Under in back-to-back games and have scored 2 or fewer runs in each of their last 3 games. They have scored 4 or fewer runs in each of their last 11 games.

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