San Diego Padres at Cincinnati Reds odds, picks and predictions

Analyzing Wednesday’s San Diego Padres at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (25-26) and Cincinnati Reds (20-28) play the 2nd game of a 3-game set at Great American Ball Park Wednesday. First pitch is scheduled for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 2-2

The Padres have lost back-to-back games after falling 2-0 against the Reds Tuesday and failing to cash as -113 road favorites. San Diego was unable to facilitate any offense for the 2nd game in a row. RHP Joe Musgrove allowed 0 ER in 3 innings and picked up the loss.

Cincinnati snapped a 3-game losing streak with its win Tuesday as a +104 home underdog. The Reds were held to just 3 hits but scored both of their runs in the 2nd inning. SS Elly De La Cruz had the only RBI of the game, and LHP Andrew Abbott allowed 5 hits in 7 innings to pick up the win.

Padres at Reds projected starters

RHP Michael King vs. RHP Nick Martinez

King (3-4, 4.31 ERA) makes his 10th start and 11th appearance. He has a 1.36 WHIP, 4.3 BB/9 and 10.2 K/9 in 54 1/3 innings.

  • Padres are 6-4 in his outings, including 2-4 in his last 6
  • Has allowed 4 ER or more in 4 of his last 7 starts
  • Has allowed 26 ER and 11 HR this season while striking out 61 and walking 26

Martinez (1-2, 4.23 ERA) makes his 5th start and 11th appearance. He has a 1.20 WHIP, 1.2 BB/9 and 6.8 K/9 in 38 1/3 innings.

  • Reds are 4-6 in his outings
  • Has allowed 18 ER and 2 HR while striking out 29 and walking 5

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Padres at Reds odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:56 a.m. ET.

  • Moneyline (ML): Padres -125 (bet $125 to win $100) | Reds +105 (bet $100 to win $105)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+135) | Reds +1.5 (-160)
  • Over/Under (O/U): 9.5 (O: +100 | U: -120)

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Padres at Reds picks and predictions

Prediction

Padres 4, Reds 3

Moneyline

BET PADRES (-125).

The Padres have won 3 of their last 5 games, all on the road, and held opponents to 3 or fewer runs in 4 of their last 5. While they lost to the Reds Tuesday, they held their offense to just 3 hits. Cincinnati has lost 7 of its last 10 games, including 3 of its last 4. It has scored 3 or fewer runs in 5 of its last 6.

Run line/Against the spread

PASS.

While the run line may be worth a 2nd look for the Padres -1.5 (+135), with their recent offensive woes — being held scoreless in back-to-back games — the moneyline is the better play.

Over/Under

BET UNDER 9.5 (-120).

While both pitchers have an ERA above 4.00, both offenses have been struggling as of late. The Padres have been held scoreless in 3 of their last 6 games and scored 4 or fewer runs in 8 of their last 10, while the Reds have scored 3 or fewer in 5 of their last 6.

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