San Diego Padres at Boston Red Sox odds, picks and predictions

Analyzing Saturday’s San Diego Padres at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (45-41) and Boston Red Sox (43-38) face off in Game 2 of a 3-game series Saturday. First pitch from Fenway Park is set for 4:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: San Diego leads 1-0

San Diego routed Boston 9-2 in Friday’s series opener while covering as a +139 road underdog. The Padres scored all 9 of their runs in the 5th inning after being down 1-0 entering the inning. San Diego has won 4 straight.

RHP Nick Pivetta picked up the loss, pitching 4 innings while allowing 5 ER, 7 H and 1 BB with 4 K. The Red Sox have lost back-to-back games.

Padres at Red Sox projected starters

RHP Michael King vs. RHP Tanner Houck

King (5-5, 3.75 ERA) makes his 17th start and 18th appearance. He has a 1.29 WHIP, 3.7 BB/9 and 10.5 K/9 through 93 2/3 innings.

  • Last start: Loss, 6 IP, 5 ER, 9 H, 1 BB, 8 K in a 6-2 loss vs. Milwaukee Sunday
  • Career vs. Boston: 2-4, 5.20 ERA (27 2/3 IP, 16 ER), 28 H, 8 BB, 29 K across 2 starts and 10 relief appearances

Houck (7-5, 2.18 ERA) makes his 17th start. He has a 0.97 WHIP, 1.6 BB/9 and 8.8 K/9 through 103 1/3 innings.

  • Last start: No-decision, 6 2/3 IP, 2 ER, 5 H, 1 BB, 7 K in a 7-6 win over Toronto Monday
  • Leads league with 2.18 ERA
  • First career start vs. San Diego

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Padres at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:40 a.m. ET.

  • Moneyline (ML): Padres +115 (bet $100 to win $115) | Red Sox -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres +1.5 (-175) | Red Sox -1.5 (+145)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Padres at Red Sox picks and predictions

Prediction

Padres 6, Red Sox 4

Moneyline

LEAN PADRES (+115). 

San Diego has won 4-straight and is 2-0 in its last 2 on the road while Boston has dropped back-to-back home games. The Padres are also 8-2 in their last 10 overall.

This is a very slight lean as Boston is 7-3 in its last 10 overall and 6-4 in its last 10 vs. San Diego.

Run line/Against the spread

PASS. 

I like the Padres to cover here as they are 44-42 ATS this season while the Red Sox are only 36-45 ATS on the year, but they are not worth the risk of betting on as +1.5 (-160) underdogs. Bet on the moneyline and/or total instead.

Over/Under

BET OVER 8.5 (-115). 

The Over has hit in each of Boston’s last 4 games and is 7-3 in its last 10 overall, also hitting in 4 consecutive home games for the Red Sox. For San Diego, the Over has hit in each of its last 8 games.

Be aware that the Under is 6-3-1 in the last 10 San Diego-Boston matchups.

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