Pittsburgh Pirates at Tampa Bay Rays odds, picks and predictions

Analyzing Wednesday’s Pittsburgh Pirates vs. Tampa Bay Rays odds and lines, with expert MLB picks, predictions and best bets.

The Pittsburgh Pirates (20-10) play the middle outing of a 3-game interleague series with the Tampa Bay Rays (24-6) Wednesday at Tropicana Field in St. Petersburg, Fla. First pitch is scheduled for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Pirates vs. Rays odds and make our expert MLB picks and predictions for the best bets.

Season series: Rays lead series 1-0 after going 3-0 in 2022

The Pirates, leading the NL Central Division, suffered the 4-1 setback in the series opener Tuesday. Despite the loss, the Bucs still lead the NL Central by 1½ games over the Milwaukee Brewers.

Pittsburgh lost back-to-back games for the 1st time since April 1-2 in Cincinnati. The Pirates also saw an 8-game cover streak on the run line as an underdog snapped.

The AL East-leading Rays, with the best record in baseball, are 7-2 in the 2nd game of a series this season. Tampa Bay cashed the Under on Tuesday, allowing just the single run, but the Rays are averaging 8.4 runs per game (RPG) across the last 5 outings.

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Pirates at Rays projected starters

RHP Mitch Keller vs. LHP Shane McClanahan

Keller (3-0, 3.53 ERA) makes his 7th start. He has a 1.21 WHIP, 3.0 BB/9 and 10.1 K/9 in 35 2/3 innings.

  • Last start: W, 6 IP, 2 ER, 5 H, 1 BB, 10 K in 6-2 home win vs. Los Angeles Dodgers Thursday — his 5th straight quality start (QS)
  • Road splits this season: 1-0, 4.08 ERA (17 2/3 IP, 8 ER), .239 opponent batting average (OBA) in 3 starts
  • Is 1-0 with a 2.08 ERA with 4 BB and 14 K in 13 IP in 2 starts in interleague games this season

McClanahan (5-0, 2.12 ERA) makes his 7th start. He has a 1.09 WHIP, 3.7 BB/9, 11.1 K/9 in 34 IP innings.

  • Last start: W, 5 IP, 2 ER, 5 H, 2 BB, 5 K in 14-5 road win vs. Chicago White Sox Thursday
  • Home splits this season: 2-0, 1.59 ERA (17 IP, 3 ER), .153 opponent batting average (OBA) in 3 starts
  • Won his only interleague start April 5 in Washington, allowing 2 ER, 5 H and 4 BB with 6 K across 6 IP

Pirates at Rays odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:03 a.m. ET.

  • Moneyline (ML): Pirates +170 (bet $100 to win $170) | Rays -210 (bet $210 to win $100)
  • Run line (RL)/Against the spread (ATS): Pirates +1.5 (-125) | Rays -1.5 (+105)
  • Over/Under (O/U): 7 (O: -115 | U: -105)

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Pirates at Rays picks and predictions

Prediction

Rays 4, Pirates 2

Moneyline

The Rays (-210) will cost you more than 2 times your potential return, and that’s quite expensive for a standalone play, even though Tampa Bay has been money at home.

PASS, and look to the home line instead.

Run line/Against the spread

RAYS -1.5 (+105) are a much better play on the run line at plus-money.

Tampa Bay cashed as a favorite on the run line in Tuesday’s series opener, and the Rays have covered in 3 of the last 4 as a favorite. After struggling on the run line in late April, the Rays are starting to heat up again as a favorite.

Be careful, however, as the Pirates +1.5 (-125) have cashed in 8 of the last 9 games an an underdog on the run line, although that lone non-cover was in the opener of this series.

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Over/Under

The UNDER 7 (-105) is the play, even though it’s quite a low number.

Both Keller and McClanahan should toss up plenty of donuts, however, like we saw in Tuesday’s interleague series opener.

The Under is 6-1-1 in the last 8 for the Pirates on an artificial surface, while the Under is 4-1-1 in the last 6 at home for the Rays. The Under is 3-1-1 in the last 5 in Game 2 of a series for Tampa Bay, too.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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