Philadelphia Eagles vs. San Francisco 49ers: 5 matchups to watch on defense

Philadelphia Eagles vs. San Francisco 49ers: 5 matchups to watch on defense

Cincinnati Bengals quarterback Joe Burrow (9) gets sacked by Philadelphia Eagles defensive tackle Fletcher Cox (91) during the NFL football game, Sunday, Sept. 27, 2020, in Philadelphia. (AP Photo/Chris Szagola)

4. Fletcher Cox-Malik Jackson-Javon Hargrave vs. 49ers IOL

Both Mullens and Garoppolo like to hold the ball when they are passing and the Eagles could find some pass rush opportunities within the 49ers’ interior offensive line.

The Niners have a pair of stout offensive tackles in LT Trent Williams and RT Mike McGlinchey.  Starting center Weston Richburg is on the PUP list, and Ben Garland has filled in, while at guard,  Laken Tomlinson and RG Daniel Brunskill are vulnerable and the latter is a former tight end.