The Penn State Nittany Lions and Purdue Boilermakers open the 2022 season with a Thursday night Big Ten battle in West Lafayette, Ind. Kickoff at Ross-Ade Stadium is slated for 8 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Penn State vs. Purdue odds, and make our expert college football picks and predictions.
Last season, Penn State was 5-0 through Oct. 2, but then fell apart the rest of the way to finish with a 7-6 mark. The Nittany Lions had a little bit of Nebraska-itis over the course of its disappointing season, going 0-4 in games decided by 1 score.
Purdue — which has lost 9 in a row to Penn State — went 9-4 last season. Bolstered by a strong aerial attack, the Boilermakers led the Big Ten West in points per game at 29.1. Purdue averaged 355.4 passing yards per contest. It went 2-2 against ranked foes, beating Iowa and Michigan State.
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Penn State at Purdue odds
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:01 a.m. ET.
- Money line: Penn State -180 (bet $100 to win $180) | Purdue +145 (bet $145 to win $100)
- Against the spread (ATS): Penn State -3.5 (-108) | Purdue +3.5 (-112)
- Over/Under (O/U): 52.5 (O: -112 | U: -108)
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Penn State at Purdue picks and predictions
Prediction
Penn State 24, Purdue 21
Money line
A lot of juice to overcome here. Too much, so PASS.
Against the spread
The Thursday night under the lights mixes with some program mojo and makes Purdue a worthwhile consideration here.
For for the host Boilermakers to hang around in a 1-score game. The lean is a small one. Consider a partial-unit play on PURDUE +3.5 (-112).
Over/Under
The Under went 2-5 in Purdue’s last 7 games in 2021. But it was 6-0 through Oct. 16.
Penn State played in 3 straight Unders to open the 2021 season. Overall, the Under went 10-3 in Lions games.
And that’s the lean in Thursday’s lid-lifter, with the offense being a half-step behind the defense. BACK THE UNDER 53.5 (-108).
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