Oregon at Colorado odds, picks and predictions

Analyzing Saturday’s Oregon at Colorado odds and lines, with college football expert picks, predictions and best bets.

The Oregon Ducks (7-1, 5-0 Pac-12) travel to Boulder to battle the Colorado Buffaloes (1-7, 1-4) Saturday at 3:30 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook‘s lines around the Oregon vs. Colorado odds, and make our expert college football picks and predictions.

Oregon is No. 8 in the AFCA Coaches Poll powered by USA TODAY sports and also No. 8 in the initial College Football Playoff rankings. The Buffaloes are nowhere near a match for the Ducks on the field.

Since Oregon’s 49-3 loss to Georgia in Week 1, the Ducks have averaged 48.0 points per game (PPG) and run off 7 wins in a row. Even against their stiffest competition, then No. 10 UCLA, they won 45-30 in a game not as close as the score makes it seem.

Colorado was lucky to get a win this season against a Cal team that was overlooking the Buffaloes. In 5 conference games, Colorado has averaged 20.0 PPG, while allowing 37.0 PPG. The Oregon defense — with LBs Noah Sewell and Justin Flowe — is nasty and Colorado will be lucky to score 20 points. With Ducks QB Bo Nix having 8 passing TDs and 6 rushing TDs in his last 3 games, Colorado can only hope to hold Oregon under 37.

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Oregon at Colorado odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 5:46 p.m. ET.

  • Moneyline (ML): Oregon -10000 (bet $10,000 to win $100) | Colorado +1500 (bet $100 to win $1,500)
  • Against the spread (ATS): Oregon -31.5 (-110) | Colorado +31.5 (-110)
  • Over/Under (O/U): 62.5 (O: -112 | U: -108)

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Oregon at Colorado picks and predictions

Prediction

Oregon 55, Colorado 10

Moneyline

AVOID. Oregon (-10000) will win, but wagering $10,000 to win $100 is never worth the risk. Do not wager anything on the ML here.

Against the spread

BET OREGON -31.5 (-110).

Oregon’s Nix has been a different player since the Week 1 Georgia loss. He has 14 TDs in his last 3 games, including 3 passing TDs and 3 rushing TDs against Cal last week.

The Buffaloes defense is terrible, having given up 185 points in 5 conference games. Colorado will be heavily outmatched, making OREGON -31.5 (-110) my FAVORITE BET in the game.

Over/Under

LEAN OVER 62.5 (-112)

The only reason this is not my best bet is that Oregon may not give up enough points to get to the Over.

If Colorado does get to 10 points, the Over should hit. But if Colorado is as inept as anticipated, cashing an Over ticket could be iffy … even in garbage time.

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