New York Yankees at San Francisco Giants odds, picks and predictions

Analyzing Friday’s New York Yankees at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The New York Yankees (39-19) and San Francisco Giants (29-28) open a 3-game set at Oracle Park Friday. First pitch is scheduled for 10:15 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Yankees vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Yankees won 2-1 last season

The Yankees took 2 of 3 games at the Los Angeles Angels Tuesday through Thursday, winning 8-3 as -163 favorites in the series finale with the Over (8.5) hitting. CF Aaron Judge hit his 275th career HR, and RF Juan Soto capped off a 5-run 7th inning with a bases-clearing triple.

The Giants failed to complete a 3-game sweep of the Philadelphia Phillies, losing 6-1 as +113 home underdogs Wednesday. The Under (7.5) hit for a 2nd straight game with San Francisco scoring just 1 run in each outing.

Yankees at Giants projected starters

RHP Marcus Stroman vs. RHP Jordan Hicks

Stroman (4-2, 2.76 ERA) makes his 12th start. He has a 1.24 WHIP, 3.9 BB/9 and 7.7 K/9 in 62 innings.

  • Last start: Win, 6 IP, 0 ER, 3 H, 1 BB, 5 K in 4-1 victory at San Diego Padres Saturday
  • 2024 road stats: 3-0, 1.98 ERA (27 1/3 IP, 6 ER), 1.24 WHIP in 5 starts
  • Career vs. Giants: 2-2, 3.34 ERA (29 2/3 IP, 11 ER), 1.48 WHIP in 5 starts, including 1-0 with a 2.70 ERA (6 2/3 IP, 2 ER) in 1 start last season

Hicks (4-1, 2.33 ERA) makes his 12th start. He has a 1.09 WHIP, 2.9 BB/9 and 7.4 K/9 in 58 innings.

  • Last start: No-decision, 5 IP, 1 ER, 2 H, 2 BB, 8 K in 7-2 win in 10 innings at New York Mets Saturday
  • 2024 home stats: 2-0, 1.85 ERA (34 IP, 7 ER), 0.94 WHIP in 6 starts
  • Career vs. Yankees: 0-0, 0.00 ERA (5 2/3 IP, 0 ER), 0.53 WHIP in 5 relief appearances

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Yankees at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 4:22 p.m. ET.

  • Moneyline (ML): Yankees -135 (bet $135 to win $100) | Giants +110 (bet $100 to win $110)
  • Run line (RL)/Against the spread (ATS): Yankees -1.5 (+125) | Giants +1.5 (-155)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Yankees at Giants picks and predictions

Prediction

Giants 4, Yankees 3

Moneyline

The GIANTS (+110) have won 6 of their last 7 games at Oracle Park, and Hicks has allowed 2 earned runs or fewer in all 6 of his home starts this season.

New York had scored a total of just 7 runs over its previous 3 road games before exploding for 8 runs against the Angels Thursday. Stroman has looked good in his last 2 road starts, allowing just 5 hits across 12 scoreless innings, but it’s unlikely that he can maintain that level of production.

BET GIANTS (+110).

Run line/Against the spread

San Francisco +1.5 (-155) should hit, but the plus odds on the ML are more attractive with Hicks on the mound at home, where he has yet to lose a decision this season.

PASS. Bet the ML and/or total instead.

Over/Under

The Yankees were on a 4-0 run to the Under before Thursday’s 8-3 victory, and the Under has hit in back-to-back games for the Giants. Stroman hasn’t allowed a run in his last 2 road starts, and Hicks has given up just 1 earned run 5 times over his last 6 outings at Oracle Park.

BET UNDER 7.5 (-105).

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