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The New York Yankees (35-17) and San Diego Padres (27-26) begin a 3-game interleague series Friday at Petco Park. First pitch is scheduled for 9:40 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Yankees vs. Padres odds and make our expert MLB picks and predictions for the best bets.
Season series: First meeting; Yankees won 2-1 last season
The Yankees have the best record in the American League, percentage points ahead of the surprising Cleveland Guardians. They’re also 2nd-best in the majors behind the Philadelphia Phillies at 37-14.
New York dropped the first 2 games against the Seattle Mariners, but bounced back with a pair of wins Tuesday and Wednesday. It is 9-2 across the past 11 games, and the Over has cashed in 4 of the past 5 for New York.
The Padres took 2 of 3 from the Cincinnati Reds while winning 3 of 4 games from the Atlanta Braves, going 5-2 on the 7-game road trip. The Over is 7-3 in the past 10 games for San Diego.
Yankees at Padres projected starters
LHP Carlos Rodon vs. RHP Yu Darvish
Rodon (5-2, 3.27 ERA) makes his 11th start. He has a 1.20 WHIP, 2.6 BB/9 and 9.0 K/9 in 55 innings.
- Last start: Win, 6 IP, 2 ER, 4 H, 1 HR, 2 BB, 6 K in 7-2 home win vs. Chicago White Sox Sunday
- 2024 road splits: 2-2, 4.25 ERA (29 2/3 IP, 14 ER), 1.45 WHIP, .273 opponents’ batting average (OBA), 32 K across 6 starts
Darvish (4-1, 2.08 ERA) makes his 10th start. He has a 0.90 WHIP, 2.5 BB/9 and 8.7 K/9 in 47 2/3 innings.
- Last start: Win, 7 IP, 0 ER, 2 H, 1 BB, 9 K (99 pitches) in 9-1 road win vs. Atlanta Braves Sunday
- 2024 home splits: 2-1, 2.35 ERA (30 2/3 IP, 8 ER), 0.98 WHIP, .193 OBA, 30 K in 6 starts
- Last 4 starts: 4-0, 0.00 ERA (24 IP), 10 H, 3 BB, 24 K
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Yankees at Padres odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:59 a.m. ET.
- Moneyline (ML): Yankees -116 (bet $116 to win $100) | Padres -102 (bet $102 to win $100)
- Run line (RL)/Against the spread (ATS): Yankees -1.5 (+146) | Padres +1.5 (-178)
- Over/Under (O/U): 7.5 (O: -110 | U: -110)
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Yankees at Padres picks and predictions
Prediction
Padres 3, Yankees 2
Moneyline
The PADRES (-102) have the white-hot Darvish on the hill, and they’re short ‘dogs at home. Take advantage.
The last time Darvish allowed a run was on the road against the Los Angeles Dodgers April 14, an abbreviated start which landed him on the injured list due to a tight neck. He has returned better than ever, twirling 24 consecutive scoreless frames.
The Yankees (-116) have the best record in baseball, but San Diego is the play due to the pitching matchup. The southpaw Rodon has been a little giving on the road.
Run line/Against the spread
The Padres +1.5 (-178) are a little too pricey if you would like a little insurance and just can’t bring yourself to play San Diego straight up for some reason.
PASS, and just play Darvish and the Padres straight up for a better value.
Over/Under
UNDER 7.5 (-110) is a low number, and each of these teams have been cashing the Over on the regular. However, this is a strong pitching matchup, with Darvish posting donuts over his past 4 outings.
The Over is actually 3-1 in Darvish’s past 4 starts since returning, mainly because San Diego has been providing plenty of support. However, the Padres won’t pile up runs on the Yankees. The Under is 7-2-1 in New York’s past 10 games on the road, too.
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