Milwaukee Brewers at San Diego Padres odds, picks and predictions

Analyzing Friday’s Milwaukee Brewers at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

The Milwaukee Brewers (9-4) and San Diego Padres (7-7) continue a 4-game series Friday. First pitch at Petco Park is at 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Brewers vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Milwaukee leads 1-0

The Brewers took Thursday’s series opener 4-3 in 10 innings. Milwaukee is 2-2 on its first road trip of the series, a 10-gamer that started with a 2-1 series loss at the Arizona Diamondbacks over the weekend.

The Padres have lost 2 games in a row and 3 of their last 4. San Diego banged out a .775 OPS in its first 10 games but has slashed a mere .181/.283/.299 (.582 OPS) across those 4 games.

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Brewers at Padres projected starters

LHP Eric Lauer vs. RHP Michael Wacha

Lauer (1-1, 7.71 ERA) is tabbed for his 3rd start of the 2023 season. He has a 1.82 WHIP, 4.8 BB/9 and 9.6 K/9 through 9 1/3 IP.

  • Current San Diego batters own an aggregate .858 OPS against him
  • Logged a 3.69 ERA and 1.22 WHIP in 158 2/3 IP last season but posted a 4.76 ERA over 81 1/3 IP on the road
  • Allowing 22 runs in 11 2/3 IP in spring training

Wacha (2-0, 3.00 ERA) makes his 3rd start. He has a 1.00 WHIP, 3.0 BB/9 and 9.0 K/9 through 12 IP.

  • Has run hot and cold through his first 2 starts, allowing 6 runs in his debut on April 1 and 0 R last time out on Saturday
  • Owns a 4.04 ERA and 1.30 WHIP across 227 career games

Brewers at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:05 a.m. ET.

  • Moneyline: Brewers +140 (bet $100 to win $140) | Padres -165 (bet $165 to win $100)
  • Run line (RL)/Against the spread (ATS): Brewers +1.5 (-145) | Padres -1.5 (+120)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Brewers at Padres picks and predictions

Prediction

Padres 5, Brewers 4

Moneyline

A San Diego bounce-back seems likely, but getting value on the Padres at this price appears very unlikely. PASS.

Run line/Against the spread

The Over is a likable play here. The Padres figure as the most appealing side, but even there it is only palatable as a partial-unit play if the return goes up to +125. PASS.

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Over/Under

It will be a cool night in pitcher-friendly Petco Park. However, an outward breeze is expected and both starters are fly-ball pitchers. Lauer and Wacha have benefitted from favorable batting-average-on-balls-in-play (BABIP) figures over the last 2 seasons (2022-23). Put the Milwaukee bullpen (.244 BABIP) in that same bin through the first couple of weeks of this season.

The Milwaukee offense is about league average. A scuffling San Diego attack (4.26 runs per game, 23rd MLB) is on its best side against left-handers, and the Friars have good numbers against Lauer. The Padres have been hamstrung by a .200 batting average with runners in scoring position. That figure comes alongside an unlucky .200 BABIP.

The back ends of the bullpens are not in shape.

BACK THE OVER 8.5 (-115).

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