Michigan State at Michigan odds, picks and predictions

Analyzing Saturday’s Michigan State at Michigan odds and lines, with college football expert picks, predictions and best bets.

The Michigan State Spartans (3-4, 1-3 Big Ten) square off against the No. 4 Michigan Wolverines (7-0, 4-0) Saturday at Michigan Stadium in Ann Arbor. Kickoff is scheduled for 7:30 p.m. ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the Michigan State vs. Michigan odds, and make our expert college football picks and predictions.

The Spartans began the season with 2 straight wins before suffering 4 straight losses, including 3 conference losses to Ohio State (49-20), Maryland (27-13) and Minnesota (34-7). Michigan State bounced back 2 weeks ago with a 34-28 double-overtime win over Wisconsin, covering the spread as a 7-point underdog.

The Wolverines continue to look like one of the best teams in the nation after steamrolling then-No. 10 Penn State 41-17 in their last game 2 weeks ago. Michigan will look to snap a 2-game losing streak to Michigan State Saturday in front of its home crowd.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

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Michigan State at Michigan odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:05 a.m. ET.

  • Moneyline (ML): Michigan State +900 (bet $100 to win $900) | Michigan -2000 (bet $2,000 to win $100)
  • Against the spread (ATS): Michigan State +23.5 (-112) | Michigan -23.5 (-108)
  • Over/Under (O/U): 55.5 (O: -107 | U: -115)

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Michigan State at Michigan picks and predictions

Prediction

Michigan 45, Michigan State 17

Moneyline

AVOID the moneyline in this game as you shouldn’t even consider wagering on Michigan (-2000) to win straight up. The Wolverines are more than capable of defeating this iteration of the Spartans, but the minuscule return you’ll receive if Michigan wins isn’t worth the risk.

Against the spread

Michigan State has found ways to keep it close with Michigan, but this feels like a year where coach Jim Harbaugh’s team imposes its will on its rivals. WOLVERINES -23.5 (-108) is where I’ll lean in this game as the Spartans won’t have an answer for RB Blake Corum and they’ll turn the ball over a couple of times, leading to more points for Michigan.

The Wolverines are 4-3 ATS overall this season and are 3-2 ATS at home.

Over/Under

Give me the OVER 55.5 (-107) with the Wolverines capable of scoring most of the points themselves. Michigan put up 41 points on a Penn State defense 2 weeks ago that allowed an average of only 14.8 points per game before taking on the Wolverines.

This feels like a game where the Wolverines run up the score on the Spartans to avenge 2 straight losses against them while Michigan State scores some late points to help us hit the OVER 55.5 (-107).

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