Miami Marlins at Chicago White Sox odds, picks and predictions

Analyzing Friday’s Miami Marlins at Chicago White Sox odds and lines, with MLB expert picks, predictions and best bets.

The Miami Marlins (35-28) and Chicago White Sox (28-36) meet Friday to kick off a 3-game series. First pitch from Guaranteed Rate Field is set for 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Marlins vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting since 2019 when White Sox won 2 of 3

Miami won 6-1 as -182 home favorites Wednesday vs. the Kansas City Royals to complete a 3-0 series sweep. That game ended a 9-game homestand for the Marlins, who went 7-2 during that stretch. The Marlins have now won 6 in a row heading into a 9-game road stretch.

Chicago lost 3-0 as +120 road underdogs Thursday vs. the New York Yankees in 2nd game of a doubleheader after winning the opener 6-5. That loss ended a 5-game winning streak for the White Sox. The White Sox are 6-4 in their last 10 and are 16-15 at home on the year.

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Marlins at White Sox projected starters

RHP Eury Perez vs. RHP Dylan Cease

Perez (3-1, 2.25 ERA) makes his 6th career start. He has a 1.17 WHIP, 4.1 BB/9 and 9.0 K/9 in 24 innings.

  • Last outing: Win, 5 IP, 0 ER, 4 H, 1 BB, 5 K in a 12-1 home win Saturday vs. Oakland Athletics
  • The 20-year-old rookie making 1st career start vs. Chicago

Cease (3-3, 4.63 ERA) makes his 14th start. He has a 1.37 WHIP, 4.2 BB/9 and 9.8 K/9 in 68 innings.

  • Last outing: No-decision, 5 1/3 IP, 1 ER, 2 H, 3 BB, 6 K in a 2-1 home win Friday vs. Detroit Tigers
  • First career start vs. Miami

Marlins at White Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:30 a.m. ET.

  • Moneyline (ML): Marlins +120 (bet $100 to win $120) | White Sox -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Marlins +1.5 (-165) | White Sox -1.5 (+140)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Marlins at White Sox picks and predictions

Prediction

Marlins 4, White Sox 3

Moneyline

LEAN MARLINS (+120).

The Marlins have won 6 in a row, are 6-0 in their last 6 games on grass, and  are 11-0 in their last 11 interleague games vs. a right handed starter. With the White Sox hot as well, 5-1 in their last 6, the Marlins advantage here is marginal at best. Bet lightly.

Run line/Against the spread

PASS. 

The line is simply not worth the juice; bet on the moneyline and/or O/U instead.

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Over/Under

BET UNDER 8 (-105).

For Chicago the Under is 5-1 in their last 6 overall and 5-0 in Cease’s last 5 Friday starts.

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