The Louisville Cardinals (12-5 overall, 7-4 ACC) visit the Duke Blue Devils (11-8, 9-6) in a Saturday evening (6 p.m. ET) contest at Cameron Indoor Stadium in Durham, N.C. Below, we analyze the Louisville-Duke odds and lines, with NCAA college basketball picks and predictions.
Louisville at Duke: Odds, spread and lines
Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 8:00 a.m. ET.
- Money line: Louisville +200 (bet $100 to win $200) | Duke -250 (bet $250 to win $100)
- Against the spread/ATS: Louisville +5.5 (-110) | Duke -5.5 (-110)
- Over/Under: 142.5 (O: -110 | U: -110)
Louisville at Duke: Three things to know
- Duke has been on the upswing in recent weeks. Since losing, 70-65, at Louisville Jan. 23, Duke is 6-3, and its three losses were by a combined 10 points. DU heads into Saturday’s game on a four-game win streak. Over that quartet of victories, the Devils have shot a robust 44.2% from 3-point range and 55.8% overall.
- For Louisville, the Jan. 23 win against Duke came amid a spate of setbacks, both on the floor and in getting through the team’s schedule. The Cardinals have played just three games this month, and they are 3-4 since Jan. 16.
- The Cards’ second-leading scorer and assist man, G David Johnson is tabbed as questionable (undisclosed) for Saturday’s game. Johnson and his 12.7 PPG were out of the lineup in a Tuesday win over Notre Dame. Louisville also has a couple other injuries further down the rotation chart.
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Louisville at Duke: Odds, lines, predictions and picks
Prediction
Duke 76, Louisville 68
Money line (ML)
The UL defense, allowing 65.8 points per game, ranks fourth in the ACC. But Duke has all the momentum on its side. The Devils are at their best against slower-tempo teams, and the Cardinals are a bottom-third bunch in that category. Look for DU to leverage good looks inside and put forth a strong effort in this contest on home hardwood.
TAKE DUKE -250.
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Against the spread (ATS)
The Cardinals are 0-5 ATS in their last five games as a road underdog. Over the last eight games of this series, the home team is 5-2-1 ATS.
Look for a youthful-and-coming-together Duke five to get this one into three-possession territory in a home-court revenge win.
BACK THE BLUE DEVILS -5.5 (-110).
Over/Under (O/U)
Respect the well-constructed total here: PASS.
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