Los Angeles Dodgers at San Francisco Giants odds, picks and predictions

Analyzing Wednesday’s Los Angeles Dodgers at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Los Angeles Dodgers (29-15) and San Francisco Giants (19-25) wrap up a 3-game set at Oracle Park Wednesday. First pitch is scheduled for 9:45 pm. ET. Let’s analyze BetMGM Sportsbook’s lines around the Dodgers vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Dodgers lead 5-0

The Dodgers won 10-2 as -177 road favorites in the 2nd game of the series Tuesday as the Over (8.5) hit. DH Shohei Ohtani had 3 hits, including a solo shot and an RBI double, for L.A., which has won back-to-back games after losing 2 of 3 at the San Diego Padres May 10-12.

The Giants have lost 2 straight games and 4 of their last 6. They have also dropped 6 consecutive meetings with the Dodgers dating back to last year.

Dodgers at Giants projected starters

TBD vs. RHP Logan Webb

The Dodgers will have a bullpen game. RHP Michael Grove (1-2, 5.64 ERA) and LHP Ryan Yarbrough (3-1, 2.56 ERA) will probably make appearances.

  • Grove 2024 road stats: 0-2, 5.91 ERA (10 2/3 IP, 7 ER), 1.31 WHIP in 1 start and 6 relief appearances
  • Yarbrough 2024 road stats: 0-0, 0.73 ERA (12 1/3 IP, 1 ER), 0.49 WHIP in 5 relief appearances

Webb (3-4, 3.38 ERA) makes his 10th start. He has a 1.34 WHIP, 2.4 BB/9 and 7.1 K/9 in 53 1/3 IP.

  • Last start: Loss, 7 IP, 2 ER (3 R), 8 H, 2 BB, 6 K in 4-2 home defeat vs. Cincinnati Reds Friday
  • 2024 home stats: 2-1, 1.24 ERA (29 IP, 4 ER), 1.04 WHIP in 4 starts
  • Career vs. Dodgers: 3-6, 4.41 ERA (67 1/3 IP, 33 ER), 1.34 WHIP in 13 starts, including 1-1 with a 2.08 ERA (13 IP, 3 ER) in 2 starts last season

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Dodgers at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:37 p.m. ET.

  • Moneyline (ML): Dodgers -145 (bet $145 to win $100) | Giants +120 (bet $100 to win $120)
  • Run line (RL)/Against the spread (ATS): Dodgers -1.5 (+115) | Giants +1.5 (-140)
  • Over/Under (O/U): 8 (O: -105 | U: -125)

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Dodgers at Giants picks and predictions

Prediction

Dodgers 6, Giants 3

Moneyline

The NL West-leading Dodgers (-145) should beat the rival Giants for a 7th straight time, but the run line at plus money is the more attractive play.

PASS. Bet the run line and/or total instead.

Run line/Against the spread

Playing L.A. as a run-line favorite has been more profitable this season than betting its ML. The Dodgers are 13-6 straight up as away favorites and 12-7 on the run line at greater odds.

BET DODGERS -1.5 (+115).

Over/Under

Webb has been impressive at home this season, but I would lean Over in this spot since the Dodgers (MLB’s best offense with 5.36 runs per game) have hit him well over the years.

The risk here, however, is that the Giants may be too shorthanded to significantly contribute toward the total, as they are still without C Patrick Bailey (concussion), OF Jung Hoo Lee (shoulder) and DH Jorge Soler (shoulder).

LEAN OVER 8 (-105).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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