Los Angeles Angels at San Diego Padres odds, picks and prediction

Analyzing Tuesday’s Los Angeles Angels at San Diego Padres odds and lines, with MLB expert picks and predictions.

The Los Angeles Angels (68-70) and San Diego Padres (73-64) play the opener of a two-game interleague series Tuesday at Petco Park. First pitch is scheduled for 10:10 p.m. ET. Let’s analyze the lines around the Angels vs. Padres odds with MLB picks and predictions.

Angels LHP Packy Naughton makes his second start and fourth appearance. He has allowed 6 runs (4 earned) on 11 hits and 5 walks with 4 strikeouts over 9 total innings spanning one start and two relief appearances.

  • Allowed 3 runs on 6 hits and 2 walks over 3 2/3 IP in his first major-league start Wednesday in a loss to the New York Yankees.
  • Faced the Padres in long relief at Angel Stadium Aug. 27, and allowed just 2 unearned runs on 3 hits and 2 walks over 4 1/3 IP.

Padres LHP Blake Snell (7-5, 4.31 ERA) makes his 26th start. He has a 1.38 WHIP, 11.8 K/9 and 5.0 BB/9 through 121 IP.

  • Walked 2 and struck out 10 across 7 no-hit and scoreless innings in a win Aug. 31 at the Arizona Diamondbacks.
  • Capped off August with a 3-1 record and 1.72 ERA, while striking out 54 batters across 36 2/3 IP over six starts.

Angels at Padres odds, lines, picks and prediction

MLB odds provided by Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 10:05 a.m. ET.

  • Money line: Angels +280 (bet $100 to win $280) | Padres -370 (bet $370 to win $100)
  • Against the spread/ATS: Angels +2.5 (-115) | Padres -2.5 (-105)
  • Over/Under: 7.5 (O: -115 | U: -107)

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Prediction

Padres 6, Angels 1

Money line (ML)

The Padres (-370) are a little on the expensive side. Snell has been dominant, but you can’t risk this much for so little reward.

AVOID, and look to the run line.

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Run line/Against the spread (ATS)

PADRES -2.5 (-105) are a tremendous play in this interleague series opener in this pitching mismatch. The southpaw Snell has been lights out lately, while Naughton is making just his second career start.

As such, take the home side to win by at least 3 runs. In four of the Padres’ last five wins, they won by 2 or more runs, too, so you can feel confident in this wager.

Over/Under (O/U)

UNDER 7.5 (-107) is the play here, as nobody has been able to get anything off of Snell lately.

The Under connected in four of the last five games for the Halos, while going 7-2 in their last nine games on the road against winning teams.

The Under is 6-2-2 in the Padres’ last 10 home games, while also cashing in four of the last five meetings between these two teams.

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