Kansas City Royals at Chicago White Sox odds, picks and predictions

Analyzing Tuesday’s Kansas City Royals at Chicago White Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Kansas City Royals (58-49) and Chicago White Sox (27-82) play the 2nd game of a 3-game series at Guaranteed Rate Field Tuesday. First pitch is scheduled for 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Royals vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Royals lead 10-1

The Royals won 8-5 as -169 favorites in the Monday opener as the Over (9.5) hit. SS Bobby Witt Jr. hit a grand slam in the 8th to cap a 6-run inning for the Royals.

White Sox 1B Andrew Vaughn homered in the 7th inning, and CF Luis Robert Jr. added 3 hits and an RBI. Chicago has lost 15 straight games, 11 of which were by 3 or more runs.

Royals at White Sox projected starters

RHP Michael Wacha vs. RHP Jonathan Cannon

Wacha (7-6, 3.65 ERA) makes his 19th start. He has a 1.22 WHIP, 2.6 BB/9 and 7.7 K/9 in 101 IP.

  • Last start: No-decision, 4 2/3 IP, 3 ER, 6 H, 1 BB, 1 K in 8-6 home loss vs. Arizona Diamondbacks Wednesday
  • 2024 road stats: 3-5, 4.09 ERA (50 2/3 IP, 23 ER), 1.18 WHIP, 7.8 K/9 in 9 starts
  • 2024 vs. White Sox: 2-1, 0.90 ERA (20 IP, 2 ER), 0.70 WHIP, 8.6 K/9 in 3 starts
  • Career vs. White Sox: 4-1, 3.30 ERA (46 1/3 IP, 17 ER), 1.01 WHIP, 9.3 K/9 in 8 starts

Cannon (1-5, 4.43 ERA) makes his 11th start and 13th appearance. The rookie has a 1.35 WHIP, 2.1 BB/9 and 6.3 K/9 in 63 IP.

  • Last start: Loss, 6 IP, 2 ER, 8 H, 2 BB, 1 K in 2-1 setback at Texas Rangers Thursday
  • 2024 home stats: 1-1, 3.24 ERA (33 1/3 IP, 12 ER), 1.14 WHIP, 6.2 K/9 in 6 appearances (4 starts)
  • Career vs. Royals: 0-1, 4.09 ERA (11 IP, 5 ER), 1.09 WHIP, 5.7 K/9 in 2 starts this year

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Royals at White Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:34 a.m. ET.

  • Moneyline (ML): Royals -200 (bet $200 to win $100) | White Sox +165 (bet $100 to win $165)
  • Run line (RL)/Against the spread (ATS): Royals -1.5 (-120) | White Sox +1.5 (+100)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Royals at White Sox picks and predictions

Prediction

Royals 5, White Sox 2

Moneyline

The Royals (-200) should hand Chicago its 16th consecutive loss, but it’s hard to beat MLB long term betting into lines with this much vig.

PASS. Bet the run line and/or total instead.

Run line/Against the spread

The White Sox cannot be trusted on the run line. They have lost 11 of their last 15 games — and 3 of Cannon’s last 4 outings — by 3 or more runs. Cannon has lost 4 straight decisions and allowed 3 or more ER in 4 of his last 6 appearances.

BET ROYALS -1.5 (-120).

Over/Under

The Under has gone 9-2 in 11 meetings between these teams. Chicago has scored 2 or fewer runs in 9 of the 11 contests, averaging just 1.5 runs per game. While the Royals exploded for 8 runs in the series opener, it’s unlikely that they score 6 or more Tuesday.

BET UNDER 9 (-115).

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