Kansas City Royals at Chicago White Sox odds, picks and predictions

Analyzing Monday’s Kansas City Royals at Chicago White Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Kansas City Royals (57-49) and Chicago White Sox (27-81) open a 3-game set at Guaranteed Rate Field Monday. First pitch is scheduled for 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Royals vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Royals lead 9-1

The Royals dropped 2 of 3 games to the visiting Chicago Cubs over the weekend. They wrapped up the series with a 7-3 loss as -176 favorites Sunday with the Over (9) hitting. Kansas City has lost back-to-back games and 4 of 5.

The White Sox have been swept in 4 straight series. They’re coming off a 6-3 loss as +111 home underdogs against the Seattle Mariners Sunday with the Over (7) cashing for a 3rd straight game. Chicago has lost 14 consecutive games, 10 of which were by 3 or more runs.

Royals at White Sox projected starters

RHP Alec Marsh vs. RHP Chris Flexen

Marsh (7-7, 4.75 ERA) makes his 19th start and 20th appearance. He has a 1.24 WHIP, 2.9 BB/9 and 8.4 K/9 through 96 2/3 innings.

  • Last start: Loss, 5 IP, 5 ER, 5 H, 2 BB, 6 K in 6-2 home defeat vs. Arizona Diamondbacks Tuesday
  • 2024 road stats: 3-4, 5.11 ERA (44 IP, 25 ER), 1.16 WHIP, 9.0 K/9 in 8 starts
  • 2024 vs. White Sox: 0-0, 4.76 ERA (5 2/3 IP, 3 ER), 1.94 WHIP, 6.4 K/9 in 2 appearances (1 start)
  • Career vs. White Sox: 1-0, 3.60 ERA (10 IP, 4 ER), 1.60 WHIP, 8.1 K/9 in 3 appearances (1 start)

Flexen (2-10, 5.25 ERA) makes his 21st start and 23rd appearance. He has a 1.42 WHIP, 3.6 BB/9 and 6.6 K/9 through 106 1/3 innings.

  • Last start: Loss, 4 2/3 IP, 3 ER, 7 H, 2 BB, 3 K in 10-2 setback at Texas Rangers Wednesday
  • 2024 home stats: 1-5, 4.80 ERA (60 IP, 32 ER), 1.47 WHIP, 6.3 K/9 in 12 starts
  • 2024 vs. Royals: 0-2, 8.18 ERA (11 IP, 10 ER), 1.55 WHIP, 6.5 K/9 in 2 starts
  • Career vs. Royals: 2-2, 4.38 ERA (24 2/3 IP, 12 ER), 1.26 WHIP, 5.8 K/9 in 5 appearances (4 starts)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Royals at White Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:42 a.m. ET.

  • Moneyline (ML): Royals -165 (bet $165 to win $100) | White Sox +140 (bet $100 to win $140)
  • Run line (RL)/Against the spread (ATS): Royals -1.5 (-105) | White Sox +1.5 (-115)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Royals at White Sox picks and predictions

Prediction

Royals 5, White Sox 2

Moneyline

The Royals (-165) have dominated the White Sox this season, going 9-1 straight up over 10 meetings and 8-2 on the run line. With how much lower the vig is on the run line, PASS on the ML.

Run line/Against the spread

The Royals’ average margin of victory against the White Sox this season has been 3.2 runs per game, and their last 7 wins against the White Sox have been by multiple runs.

Chicago has lost Flexen’s last 4 starts by 2 or more runs, and he has been the least profitable pitcher in MLB this season, according to OddsShark.com. If a bettor were to risk $100 on White Sox ML every time Flexen started a game this year, they would be down $1,415.

BET ROYALS -1.5 (-105).

Over/Under

The Under has gone 9-1 in 10 meetings between these teams. The lone Over was a 10-1 Kansas City win April 4, the 1st time these teams met this season. The White Sox have scored 2 or fewer runs in 9 of the 10 contests — they lost 5-3 April 7 in their best offensive showing in the season series — averaging 1.2 runs per game.

BET UNDER 9 (-115).

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