Jacksonville Jaguars at Buffalo Bills odds, picks and predictions

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The Jacksonville Jaguars (0-2) and the Buffalo Bills (2-0) meet for a Week 3 game Monday. Kickoff at Highmark Stadium is set for 7:30 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s NFL odds around the Jaguars vs. Bills odds, and make our expert NFL picks and predictions.

The Jaguars lost 18-13 at home to the Cleveland Browns last week. Jacksonville has had issues on offense, averaging just 15.0 points per game (PPG) in 2 games, while allowing just 19.0 PPG.

QB Trevor Lawrence has completed just 51.0% of his pass attempts for 382 yards, 1 TD and 0 INT in 2 outings, while RB Travis Etienne leads the team with just 96 rushing yards, although he has 2 scores.

The Bills have scored 31 or more points in both games. That includes a 31-10 win at the Miami Dolphins last Thursday as a 2.5-point underdog as the Under (49.5) cashed.

The weather forecast for Western New York is rather ominous, although things have improved in the past couple of days. The forecast is calling for a 40% chance of precipitation, with showers off and on throughout the game. Winds will be blowing from 8-11 MPH, too, perhaps limiting the aerial attack with the slippery conditions.

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Jaguars at Bills odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Sunday at 4:07 p.m. ET.

Moneyline (ML): Jaguars +200 (bet $100 to win $220) | Bills -250 (bet $250 to win $100)
Against the spread (ATS): Jaguars +5.5 (-110) | Bills -5.5 (-110)
Over/Under (O/U): 45.5 (O: -110 | U: -110)

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Jaguars at Bills key injuries

Jaguars

RB Tank Bigsby (shoulder) questionable
TE Evan Engram (hamstring) out
OT Cam Robinson (knee) questionable
DB Darnell Savage (quadriceps) questionable

Bills

LB Terrel Bernard (pectoral) out
CB Taron Johnson (forearm) out

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Jaguars at Bills picks and predictions

Prediction

Bills 24, Jaguars 17

Moneyline

The Bills (-250) will cost you 2 1/2 times your potential return, and that’s quite risky despite the fact Buffalo has won both its games, while the Jaguars (+200) have lost both outings.

Jacksonville could easily have won both of its 1st 2 games, losing each by a single score. This is a pesky team with some impressive skill-position players and an above-average defense. It won’t be an easy game for the home side.

PASS.

Against the spread

The BILLS -5.5 (-110) are the lean, but go very, very lightly.

Buffalo covered handily last week in Miami in Week 2, but it failed to cover at home against Arizona despite a 34-28 victory. You can expect a similar result here, especially if it is a soggy game with plenty of running.

The Jaguars +5.5 (-110) have the tools to hang with the Bills if the aerial game is limited by the weather, especially if RB Tank Bigsby is healthy enough to join Etienne in the backfield.

Over/Under

UNDER 45.5 (-110) is a solid play in the 1st of this MNF double dip.

We’re going to have a wet track, and that might mean more running, and less aerials. A ground-based offensive attack keeps the clock running, which is beneficial to Under bettors.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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