Houston Astros at San Francisco Giants odds, picks and predictions

Analyzing Tuesday’s Houston Astros at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (30-37) and San Francisco Giants (33-34) play the 2nd game of a 3-game set at Oracle Park Tuesday. First pitch is scheduled for 9:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 1-0

The Astros lost 4-3 in 10 innings as -114 road favorites in the series opener Monday as the Under (8) hit. Houston has lost back-to-back games for the 1st time since a 3-game skid May 27-29.

RF Austin Slater hit a game-winning single for the Giants, who rallied back from a 2-run deficit in the 10th inning. San Francisco has won 4 of its last 5 games.

Astros at Giants projected starters

RHP Ronel Blanco vs. RHP Jordan Hicks

Blanco (5-2, 2.78 ERA) makes his 12th start. He has a 1.05 WHIP, 3.8 BB/9 and 8.2 K/9 in 64 2/3 IP.

  • Last start: Loss, 5 2/3 IP, 4 ER, 5 H, 2 BB, 2 K in 4-2 home setback vs. St. Louis Cardinals Wednesday
  • 2024 road stats: 4-0, 2.08 ERA (30 1/3 IP, 7 ER), 1.09 WHIP, 8.6 K/9 in 5 starts

Hicks (4-2, 2.82 ERA) makes his 14th start. He has a 1.19 WHIP, 3.1 BB/9 and 7.9 K/9 in 67 IP.

  • Last start: No-decision, 3 2/3 IP, 2 ER, 6 H, 4 BB, 7 K in 9-3 win at Arizona Diamondbacks Wednesday
  • 2024 home stats: 2-1, 2.52 ERA (39 1/3 IP, 11 ER), 0.99 WHIP, 5.7 K/9 in 7 starts

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Astros at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:26 p.m. ET.

  • Moneyline (ML): Astros -105 (bet $105 to win $100) | Giants -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (+155) | Giants +1.5 (-190)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Astros at Giants picks and predictions

Prediction

Astros 3, Giants 2

Moneyline

The ASTROS (-105) are 4-1 in their last 5 outings after a loss and should bounce back against the inconsistent Giants, who are 4-7 over their last 11 games. Blanco has yet to lose a decision on the road this season, and Hicks has allowed a total of 7 runs over his last 2 starts (9 IP).

BET ASTROS (-105).

Run line/Against the spread

San Francisco +1.5 (-190) will probably hit, but it’s hard to beat MLB long term betting into markets with this much vig.

PASS. Bet the ML and/or total instead.

Over/Under

Blanco has allowed 2 ER or fewer in all 4 road starts this season, and Hicks has given up 2 or fewer runs in 6 of his 7 appearances at Oracle Park. The Under has hit in 4 of 5 games for the Astros and 3 of 4 for San Francisco.

BET UNDER 8 (-115).

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