The Hamilton Tiger-Cats (0-1) visit the Saskatchewan Roughriders (1-0) for a 10 p.m. ET kickoff Saturday at Mosaic Stadium. Below, we look at the Tiger-Cats vs. Roughriders odds and lines and make our best CFL picks, predictions and bets.
The Tiger-Cats suffered a 19-6 road loss against the Winnipeg Blue Bombers in the 2021 CFL season opener Aug. 5. QB Jeremiah Masoli completed just 24 of 41 passes for 242 yards and 1 touchdown against 2 interceptions and contributed 26 of the team’s 55 total yards on the ground.
The Roughriders are playing their second straight home game to open the season after beating the BC Lions 33-29 last week. QB Cody Fajardo went 28-for-35 through the air for 230 yards and 2 TDs against 1 INT. RB William Powell led the team with 43 rushing yards and a touchdown. The Saskatchewan defense forced 2 interceptions from Lions QB Nathan Rourke.
Tiger-Cats at Roughriders odds, spread and lines
Odds via Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 1:45 p.m. ET.
- Money line: Tiger-Cats +100 (bet $100 to win $100) | Roughriders -140 (bet $140 to win $100)
- Against the spread/ATS: Tiger-Cats +2.5 (-115) | Roughriders -2.5 (-120)
- Total: 49.5 (O: -115 | U: -120)
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Tiger-Cats at Roughriders odds, lines, predictions and picks
Prediction
Roughriders 25, Tiger-Cats 18
Money line
Back the ROUGHRIDERS (-140) as home favorites while seeking a second straight win. Saskatchewan posted a league-high 33 points in Week 1 while Hamilton struggled with a one-dimensional offense against Winnipeg in the season opener.
The home crowds make a difference in the West Division and the Tiger-Cats will enter another hostile environment on the road.
Against the spread
Roll with ROUGHRIDERS -2.5 (-120) as the more profitable bet on the home team should they win by at least 3 points.
Hamilton closed as a 1-point favorite in Winnipeg last week but took a 13-point loss. Saskatchewan failed to cover as a 6.5-point favorite in its opener but has a more conservative number to cover this week.
Over/Under
Take the UNDER 49.5 (-120) despite Saskatchewan’s high score last week. Hamilton has a much better defense than BC and we’ll need to see more from the Ti-Cats’ rushing attack before trusting them to handle their share of the combined point total.
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