Giants open as massive road underdogs vs. Bills in Week 6

The New York Giants have opened as 14.5-point road underdogs against the Buffalo Bills (-900) in Week 6.

The New York Giants have opened as mammoth underdogs for their game on Sunday night against the Buffalo Bills at Highmark Stadium in Orchard Park, New York.

As of Monday morning, the Bills were a prohibitive 14.5-point favorite with an over/under of 46.5 total points, per BetMGM.

The money line opened at an unheard-of Bills -900, Giants +600.

The Bills (3-2) had their three-game winning streak ended in London on Sunday by the Jacksonville Jaguars, 25-20.

The Giants (1-4) were crushed by the Miami Dolphins, 31-16, in South Florida this week and are awaiting MRI results on quarterback Daniel Jones’ neck.

Buffalo is 3-2 against the spread this year and have been favorites in all five of their games. The UNDER has come in three times this year to the OVER’s two.

The Giants are 0-5 versus the spread this season and four of their five games have gone UNDER.

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