The No. 8 Michigan State Spartans (9-1, 6-1 Big Ten) and No. 4 Ohio State Buckeyes (9-1, 7-0) meet noon ET Saturday at Ohio Stadium in Columbus, Ohio. Below, we look at the Michigan State vs. Ohio State odds and lines; check back for our college football picks and predictions.
Michigan State bounced back from its Nov. 6 Purdue loss to defeat Maryland 40-21 Saturday. RB Kenneth Walker III logged 30 totes for 143 yards and two touchdowns, as the Spartans ran their home record to 5-0. The nation’s 27th-best rushing team (199.0 yards per game) recorded 194 yards on the ground and has compiled 180 or more yards in three straight games and in eight games overall this season.
The Buckeyes played Purdue Saturday and got their offense back on track after a couple of subpar weeks. An Ohio State offense ranked first in the nation (550.3 total yards per game) cranked out a season-high 624 total yards in the contest. QB CJ Stroud edged further into Heisman Trophy consideration by going 31-for-38 (81.6%) for 361 yards and five TD passes.
Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.
Michigan State at Ohio State odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 8:21 a.m. ET.
- Money line: Michigan State +700 (bet $100 to win $700) | Ohio State -1200 (bet $1,200 to win $100)
- Against the spread (ATS): Michigan State +22.5, -112 (bet $112 to win $100) | Ohio State -22.5, -108 (bet $108 to win $100)
- Over/Under (O/U): 67.5, O: -108 (bet $108 to win $100) | U: -112 (bet $112 to win $100)
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2021 betting stats:
- ML: Michigan State 9-1 | Ohio State 9-1
- ATS: Michigan State 7-1-2 | Ohio State 5-4-1
- O/U: Michigan State 6-4 | Ohio State 6-4
Michigan State at Ohio State head-to-head
Ohio State beat Michigan State 51-12 last year and has won five straight games in a series that dates back to 1912. The Under has had some juice in recent OSU-MSU matchups, going 5-1 in the last six meetings and 5-0 in the last five games played at Ohio Stadium.
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