First look: Los Angeles Rams at Arizona Cardinals odds and lines

Looking at Sunday’s Los Angeles Rams at Arizona Cardinals Week 3 NFL odds, lines and trends. Here’s what you need to know.

The Los Angeles Rams (1-1) and Arizona Cardinals (1-1) meet for the first time this season Sunday. Kickoff from State Farm Stadium will be at 4:25 p.m. ET (FOX). Below, we look at Rams vs. Cardinals odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Rams held on to beat the Atlanta Falcons 31-27 in Week 2. The score was much closer than it should’ve been considering the Rams held a 28-3 lead in the 3rd quarter.

Also see: All Week 3 odds and lines

The Rams managed to win thanks to CB Jalen Ramsey‘s game-sealing interception in the final minutes despite throwing an interception, losing a fumble and having a punt blocked in the 4th quarter.

The Cardinals came from behind to beat the Las Vegas Raiders 29-23 Sunday. Arizona erased a 23-7 deficit in the second half to win in overtime. CB Byron Murphy Jr. returned a fumble 59 yards for the game-winning touchdown in OT, a dramatic comeback win for Arizona to keep pace in the NFC West.

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Rams at Cardinals odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 12:16 p.m. ET.

  • Money line (ML): Rams -200 (bet $200 to win $100) | Cardinals +165 (bet $100 to win $165)
  • Against the spread (ATS): Rams -4.5 (-105) | Cardinals +4.5 (-115)
  • Over/Under (O/U): 50.5 (O: -115 | U: -105)

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2022 betting stats

  • ML: Rams 1-1 | Cardinals 1-1
  • ATS: Rams 0-2 | Cardinals 1-1
  • O/U: Rams 1-1 | Cardinals 1-1

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Rams vs. Cardinals head-to-head

The Rams and Cardinals square off twice a year as divisional rivals, and in some cases, they meet 3 times like last season when both made the playoffs and met in the wild-card round.

The Rams have owned this rivalry since coach Sean McVay took over in 2017. They’ve gone 10-1 in 11 meetings — including last year’s playoff meeting. The Cardinals have covered the spread in just 1 of their last 10 meetings as the Rams have scored at least 30 points 8 times along that stretch. The Over/Under has been an even 5-5 split in those 10 matchups.

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