The Denver Broncos and Seattle Seahawks kick off the NFL’s Monday Night Football slate at Lumen Field. Kickoff is set for 8:15 p.m. ET (ESPN/ABC). Below, we analyze Tipico Sportsbook‘s lines around the Broncos vs. Seahawks odds, and make our expert NFL picks and predictions.
This is one of the most anticipated matchups of Week 1 as Broncos QB Russell Wilson faces his former team. Wilson appeared in 14 games last season for the Seahawks and was 6-8 as their starter. QB Geno Smith started the other 3 games, going 1-2, en route to a 7-10 season.
Wilson will start anew with Denver as he’ll try to develop a rapport with WRs Courtland Sutton and Jerry Jeudy. The Broncos also went 7-10 in 2021 but that was with QBs Teddy Bridgewater (7-7 as starter) and Drew Lock (0-3) under center. Lock now plays for Seattle, though Smith has been named the team’s starting QB, and Bridgewater is a backup with the Miami Dolphins.
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Broncos at Seahawks odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:34 p.m. ET.
- Money line (ML): Broncos -280 (bet $280 to win $100) | Seahawks +230 (bet $100 to win $230)
- Against the spread (ATS): Broncos -6.5 (-108) | Seahawks +6.5 (-112)
- Over/Under (O/U): 43.5 (O: -112 | U: -108)
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Broncos at Seahawks key injuries
Broncos
- LB Randy Gregory (shoulder/knee) questionable
- WR KJ Hamler (knee/hip) questionable
- LB Josey Jewell (calf) out
- OL Billy Turner (knee) questionable
Seahawks
- CB Artie Burns (groin) doubtful
- OL Damien Lewis (knee/ankle) questionable
- LS Tyler Ott (shoulder) out
- LB Alton Robinson (knee) out
- RB Kenneth Walker III (hernia) questionable
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Broncos at Seahawks picks and predictions
Prediction
Broncos 27, Seahawks 10
Money line
It’s safe to PASS on this money line wager.
Even with Denver being the rightful favorite, the NFL’s parity is too strong to consider putting down such a high amount of money for such a low return. Your money is better spent elsewhere unless you include Broncos (-280) in a parlay or round robin with a much higher return.
Against the spread
The BRONCOS -6.5 (-108) are the easy pick even with such a large betting line. Denver was already a strong team without Wilson last season, so the addition of the Super Bowl XLVIII champion should push their offense from below average in 2021 to, at the very least, above average in 2022.
The strongest point for Denver is its defense, which added LB Randy Gregory during free agency to rush the passer opposite LB Bradley Chubb. Those two lead the charge for what appears to be one of the NFL’s most talented defensive groups. That unit can easily hold down Smith who has a tough track record as an NFL starter (13-21 overall). Not to mention Seattle could be missing its starting left guard and possibly two defensive contributors for this matchup.
Over/Under
Play UNDER 43.5 (-108) lightly, as this one probably won’t be a high-scoring affair. The Broncos can contain Seattle’s offense which should lead to Denver getting out ahead early on. Once Denver has the lead, I’d expect a heavy running game load for RBs Javonte Williams and Melvin Gordon as they try to drain the clock.
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More NFL Week 1 coverage
- Experts: ML, ATS and OU predictions
- Recap best picks: Underdogs | 5 player props | Survivor
- Super Bowl LVII odds
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