The Indianapolis Colts (5-5) are hoping to upset the Buffalo Bills (6-3) on the road at Highmark Stadium in Week 11.
A game that has plenty of playoff implications for both sides, the Colts have yet to beat a team with a record above .500 this season. They’ll have their chance to do so against a Bills team that is led by quarterback Josh Allen, who carved up the defense during the wild-card game in the 2020 postseason.
This game will come down to a handful of matchups that will determine the outcome. Here are the key matchups to keep an eye on in the Week 11 bout: