Colorado Rockies at San Francisco Giants odds, picks and predictions

Analyzing Wednesday’s Colorado Rockies at San Francisco Giants Reds odds and lines, with MLB expert picks and predictions.

The Colorado Rockies (24-31) and San Francisco Giants (29-25) meet  Wednesday for the second game of a 3-game series at Oracle Park. First pitch is slated for a 9:45 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Rockies vs. Giants odds with MLB picks and predictions.

Season series: San Francisco leads 5-2. Colorado took game 1 of this series 5-3 Tuesday.

The Rockies had notched a 6.16 ERA over its previous 26 games, but RHP German Marquez and 3 relievers combined to pitch 8 scoreless innings after the Giants scored 3 runs in the first inning Tuesday.

The Giants were perhaps sleepwalking through much of Tuesday’s game in which they managed all of 5 hits. Tuesday’s affair was a return home after a 10-game road trip to Cincinnati, Philadelphia, and Miami.

Rockies at Giants projected starters

RHP Antonio Senzatela vs. LHP Alex Wood

Senzatela (2-3, 5.40 ERA) has registered a 1.97 WHIP, 2.1 BB/9 and 3.6 K/9 through 35 IP across 8 starts.

  • Allowed 6 earned runs on 13 hits across 5 1/3 innings last Wednesday against the Miami Marlins in his last start.
  • Owns a 9.00 ERA and 2.18 WHIP over his last 3 turns.
  • Has posted a 3.51 ERA at home and a 5.30 mark on the road since 2020.

Wood (3-5, 4.66 ERA) has made 10 starts this season. He has a 1.43 WHIP, 2.8 BB/9 and 9.3 K/9 through 48 1/3 IP.

  • Has held opponents to 3 runs or fewer in 5 of his last 6 starts.
  • Has allowed 3 ER in 9 2/3 IP in 2 starts against Colorado this season.
  • Owns a 3.20 ERA over his last 5 starts against the Rockies.

Rockies at Giants odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 10:55 a.m. ET.

  • Money line: Rockies +180 (bet $100 to win $180) | Giants -230 (bet $230 to win $100)
  • Run line (RL): Rockies +1.5 (-112) | Giants -1.5 (-108)
  • Over/Under (O/U): 8.5 (O: -122 | U: -102)

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Rockies at Giants picks and predictions

Prediction

Giants 5, Rockies 3

Money line

PASS: the best leverage to be had here is on a low-scoring game with a line watch on the run line.

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Run line/Against the spread

Colorado is tough on southpaws, but Wood’s success against the Rockies is compelling. The San Francisco port-sider has been unduly hurt by a .353 batting average on balls in play and a high rate of fly balls leaving the yard.

PASS for now, but keep an eye on this one. A play on the Giants at +100 or better has leverage.

Over/Under

Figure both offenses being a bit too far out over their skis overall. Depending on the starters, this series sets up as one for Unders having value. That angle produced a win Tuesday.

Both starters have been working through the amped-up traffic of high batting averages on balls in play.

BACK THE UNDER 8.5 (-102).

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